| Full name: DEAD-box helicase 20 | Alias Symbol: DP103|GEMIN3 | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 11218 | HGNC ID: HGNC:2743 | Ensembl Gene: ENSG00000064703 | OMIM ID: 606168 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DDX20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX20 | 11218 | 223331_s_at | 0.4002 | 0.2515 | |
| GSE26886 | DDX20 | 11218 | 223331_s_at | 0.5101 | 0.0156 | |
| GSE45670 | DDX20 | 11218 | 223331_s_at | 0.0507 | 0.7687 | |
| GSE53622 | DDX20 | 11218 | 52496 | 0.3312 | 0.0000 | |
| GSE53624 | DDX20 | 11218 | 52496 | 0.5122 | 0.0000 | |
| GSE63941 | DDX20 | 11218 | 223331_s_at | -0.1600 | 0.7468 | |
| GSE77861 | DDX20 | 11218 | 223331_s_at | 0.0308 | 0.8972 | |
| GSE97050 | DDX20 | 11218 | A_23_P63153 | 0.1734 | 0.5939 | |
| SRP007169 | DDX20 | 11218 | RNAseq | 0.5385 | 0.2043 | |
| SRP008496 | DDX20 | 11218 | RNAseq | 0.3412 | 0.1793 | |
| SRP064894 | DDX20 | 11218 | RNAseq | 0.3252 | 0.0659 | |
| SRP133303 | DDX20 | 11218 | RNAseq | 0.5253 | 0.0011 | |
| SRP159526 | DDX20 | 11218 | RNAseq | 0.0764 | 0.8226 | |
| SRP193095 | DDX20 | 11218 | RNAseq | 0.3703 | 0.0000 | |
| SRP219564 | DDX20 | 11218 | RNAseq | 0.2177 | 0.6130 | |
| TCGA | DDX20 | 11218 | RNAseq | 0.1204 | 0.0396 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDX20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX20 | 11218 | 0 | 10 | 20 | |
| GSE20123 | DDX20 | 11218 | 0 | 10 | 20 | |
| GSE43470 | DDX20 | 11218 | 0 | 8 | 35 | |
| GSE46452 | DDX20 | 11218 | 2 | 1 | 56 | |
| GSE47630 | DDX20 | 11218 | 9 | 5 | 26 | |
| GSE54993 | DDX20 | 11218 | 0 | 1 | 69 | |
| GSE54994 | DDX20 | 11218 | 7 | 4 | 42 | |
| GSE60625 | DDX20 | 11218 | 0 | 0 | 11 | |
| GSE74703 | DDX20 | 11218 | 0 | 7 | 29 | |
| GSE74704 | DDX20 | 11218 | 0 | 6 | 14 | |
| TCGA | DDX20 | 11218 | 7 | 27 | 62 |
Total number of gains: 25; Total number of losses: 79; Total Number of normals: 384.
Somatic mutations of DDX20:
Generating mutation plots.
Highly correlated genes for DDX20:
Showing top 20/905 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX20 | USP34 | 0.831437 | 3 | 0 | 3 |
| DDX20 | PPP2R5E | 0.798646 | 3 | 0 | 3 |
| DDX20 | LRRC58 | 0.796083 | 3 | 0 | 3 |
| DDX20 | ORAI1 | 0.782118 | 3 | 0 | 3 |
| DDX20 | LMBR1 | 0.777994 | 3 | 0 | 3 |
| DDX20 | M6PR | 0.775267 | 3 | 0 | 3 |
| DDX20 | ZNF597 | 0.773515 | 3 | 0 | 3 |
| DDX20 | HRH1 | 0.77293 | 3 | 0 | 3 |
| DDX20 | HERC2 | 0.772011 | 3 | 0 | 3 |
| DDX20 | SMNDC1 | 0.763961 | 4 | 0 | 4 |
| DDX20 | CDT1 | 0.76367 | 3 | 0 | 3 |
| DDX20 | RACGAP1 | 0.758565 | 3 | 0 | 3 |
| DDX20 | PLAGL2 | 0.755774 | 3 | 0 | 3 |
| DDX20 | PALB2 | 0.754062 | 3 | 0 | 3 |
| DDX20 | FAM160B1 | 0.753024 | 3 | 0 | 3 |
| DDX20 | DHX57 | 0.749869 | 4 | 0 | 3 |
| DDX20 | RECQL | 0.749132 | 3 | 0 | 3 |
| DDX20 | ZNF484 | 0.748668 | 3 | 0 | 3 |
| DDX20 | EPRS | 0.748424 | 3 | 0 | 3 |
| DDX20 | DAG1 | 0.746096 | 3 | 0 | 3 |
For details and further investigation, click here
