BOLA1

 

Full name: bolA family member 1 Alias Symbol: CGI-143
Type: protein-coding gene Cytoband: 1q21.2
Entrez ID: 51027 HGNC ID: HGNC:24263 Ensembl Gene: ENSG00000178096 OMIM ID: 613181
Drug and gene relationship at DGIdb

 

Expression of BOLA1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BOLA1 51027 219345_at 0.4190 0.3612
GSE20347 BOLA1 51027 219345_at 0.2789 0.0290
GSE23400 BOLA1 51027 219345_at 0.1260 0.0200
GSE26886 BOLA1 51027 219345_at 0.9792 0.0009
GSE29001 BOLA1 51027 219345_at 0.6535 0.0182
GSE38129 BOLA1 51027 219345_at 0.2025 0.1391
GSE45670 BOLA1 51027 219345_at 0.0231 0.9112
GSE53622 BOLA1 51027 89379 0.2747 0.0010
GSE53624 BOLA1 51027 89379 0.4600 0.0000
GSE63941 BOLA1 51027 219345_at 0.5834 0.4315
GSE77861 BOLA1 51027 219345_at 0.2293 0.0718
GSE97050 BOLA1 51027 A_33_P3354151 0.0560 0.8853
SRP007169 BOLA1 51027 RNAseq -1.0566 0.0370
SRP008496 BOLA1 51027 RNAseq 0.0937 0.8171
SRP064894 BOLA1 51027 RNAseq 0.0465 0.8905
SRP133303 BOLA1 51027 RNAseq -0.0039 0.9849
SRP159526 BOLA1 51027 RNAseq 0.5307 0.0167
SRP193095 BOLA1 51027 RNAseq 0.0004 0.9978
SRP219564 BOLA1 51027 RNAseq -0.1067 0.8117
TCGA BOLA1 51027 RNAseq 0.0943 0.3373

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by BOLA1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BOLA1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BOLA1 51027 14 0 16
GSE20123 BOLA1 51027 14 0 16
GSE43470 BOLA1 51027 6 1 36
GSE46452 BOLA1 51027 2 1 56
GSE47630 BOLA1 51027 14 0 26
GSE54993 BOLA1 51027 0 3 67
GSE54994 BOLA1 51027 15 0 38
GSE60625 BOLA1 51027 0 0 11
GSE74703 BOLA1 51027 6 1 29
GSE74704 BOLA1 51027 7 0 13
TCGA BOLA1 51027 33 15 48

Total number of gains: 111; Total number of losses: 21; Total Number of normals: 356.  


 

Somatic mutations of BOLA1:

 

Generating mutation plots.

 

Highly correlated genes for BOLA1:

 

Showing top 20/1221 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BOLA1ZSCAN210.83345404
BOLA1ATG4C0.819187303
BOLA1ZNF2510.776812303
BOLA1C20orf1940.772169303
BOLA1ZC3H12C0.75993303
BOLA1NSD10.744352303
BOLA1ZNF7040.742369303
BOLA1USP140.737801303
BOLA1ZBED10.736923404
BOLA1ZNF6910.734918605
BOLA1GCLC0.731813303
BOLA1CHCHD60.723282504
BOLA1MADD0.71937303
BOLA1PELI20.719266505
BOLA1MRPL240.71785712012
BOLA1FAM89B0.714277303
BOLA1LTBR0.712845303
BOLA1UBP10.710699403
BOLA1KRTCAP20.710215403
BOLA1CCDC1270.710158303

For details and further investigation, click here