| Full name: zinc finger C3HC-type containing 1 | Alias Symbol: NIPA | ||
| Type: protein-coding gene | Cytoband: 7q32.2 | ||
| Entrez ID: 51530 | HGNC ID: HGNC:29913 | Ensembl Gene: ENSG00000091732 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZC3HC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZC3HC1 | 51530 | 223163_s_at | 0.4957 | 0.0398 | |
| GSE26886 | ZC3HC1 | 51530 | 223163_s_at | 0.2005 | 0.3577 | |
| GSE45670 | ZC3HC1 | 51530 | 223163_s_at | 0.4717 | 0.0101 | |
| GSE53622 | ZC3HC1 | 51530 | 82217 | 0.4878 | 0.0000 | |
| GSE53624 | ZC3HC1 | 51530 | 82217 | 0.6949 | 0.0000 | |
| GSE63941 | ZC3HC1 | 51530 | 223163_s_at | 0.1143 | 0.7718 | |
| GSE77861 | ZC3HC1 | 51530 | 223163_s_at | 0.2958 | 0.0578 | |
| GSE97050 | ZC3HC1 | 51530 | A_23_P215088 | 0.1915 | 0.5146 | |
| SRP007169 | ZC3HC1 | 51530 | RNAseq | 0.9392 | 0.0287 | |
| SRP008496 | ZC3HC1 | 51530 | RNAseq | 0.6172 | 0.0316 | |
| SRP064894 | ZC3HC1 | 51530 | RNAseq | 0.8677 | 0.0000 | |
| SRP133303 | ZC3HC1 | 51530 | RNAseq | 0.4492 | 0.0365 | |
| SRP159526 | ZC3HC1 | 51530 | RNAseq | 0.5683 | 0.0025 | |
| SRP193095 | ZC3HC1 | 51530 | RNAseq | 0.4097 | 0.0000 | |
| SRP219564 | ZC3HC1 | 51530 | RNAseq | 0.0460 | 0.8866 | |
| TCGA | ZC3HC1 | 51530 | RNAseq | 0.0715 | 0.3069 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZC3HC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZC3HC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZC3HC1 | 51530 | 8 | 1 | 21 | |
| GSE20123 | ZC3HC1 | 51530 | 8 | 1 | 21 | |
| GSE43470 | ZC3HC1 | 51530 | 2 | 3 | 38 | |
| GSE46452 | ZC3HC1 | 51530 | 7 | 2 | 50 | |
| GSE47630 | ZC3HC1 | 51530 | 7 | 4 | 29 | |
| GSE54993 | ZC3HC1 | 51530 | 3 | 5 | 62 | |
| GSE54994 | ZC3HC1 | 51530 | 7 | 7 | 39 | |
| GSE60625 | ZC3HC1 | 51530 | 0 | 0 | 11 | |
| GSE74703 | ZC3HC1 | 51530 | 2 | 3 | 31 | |
| GSE74704 | ZC3HC1 | 51530 | 4 | 1 | 15 | |
| TCGA | ZC3HC1 | 51530 | 30 | 21 | 45 |
Total number of gains: 78; Total number of losses: 48; Total Number of normals: 362.
Somatic mutations of ZC3HC1:
Generating mutation plots.
Highly correlated genes for ZC3HC1:
Showing top 20/1701 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZC3HC1 | CBLB | 0.87971 | 3 | 0 | 3 |
| ZC3HC1 | SMARCAD1 | 0.799477 | 3 | 0 | 3 |
| ZC3HC1 | SYNGR3 | 0.798826 | 3 | 0 | 3 |
| ZC3HC1 | HAUS7 | 0.797269 | 3 | 0 | 3 |
| ZC3HC1 | KTI12 | 0.791274 | 3 | 0 | 3 |
| ZC3HC1 | DENND5A | 0.767692 | 3 | 0 | 3 |
| ZC3HC1 | RBBP5 | 0.765224 | 4 | 0 | 4 |
| ZC3HC1 | NSD1 | 0.763597 | 3 | 0 | 3 |
| ZC3HC1 | TUBA1B | 0.760804 | 4 | 0 | 4 |
| ZC3HC1 | DDX21 | 0.757207 | 3 | 0 | 3 |
| ZC3HC1 | ATG4C | 0.751439 | 3 | 0 | 3 |
| ZC3HC1 | SLC35B2 | 0.751265 | 3 | 0 | 3 |
| ZC3HC1 | CEP41 | 0.749351 | 7 | 0 | 7 |
| ZC3HC1 | TMF1 | 0.747068 | 3 | 0 | 3 |
| ZC3HC1 | TRAF3 | 0.744485 | 4 | 0 | 4 |
| ZC3HC1 | CDK18 | 0.743927 | 3 | 0 | 3 |
| ZC3HC1 | MRPL11 | 0.743775 | 5 | 0 | 5 |
| ZC3HC1 | FAM86C1 | 0.743368 | 3 | 0 | 3 |
| ZC3HC1 | CEP250 | 0.741188 | 3 | 0 | 3 |
| ZC3HC1 | SSRP1 | 0.738593 | 6 | 0 | 6 |
For details and further investigation, click here
