| Full name: macrophage stimulating 1 | Alias Symbol: MSP|NF15S2 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 4485 | HGNC ID: HGNC:7380 | Ensembl Gene: ENSG00000173531 | OMIM ID: 142408 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MST1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MST1 | 4485 | 216320_x_at | 0.1380 | 0.7378 | |
| GSE20347 | MST1 | 4485 | 216320_x_at | -0.1180 | 0.4371 | |
| GSE23400 | MST1 | 4485 | 216320_x_at | -0.1190 | 0.0041 | |
| GSE26886 | MST1 | 4485 | 216320_x_at | -0.3373 | 0.1318 | |
| GSE29001 | MST1 | 4485 | 216320_x_at | -0.0514 | 0.8815 | |
| GSE38129 | MST1 | 4485 | 205614_x_at | -0.1882 | 0.1689 | |
| GSE45670 | MST1 | 4485 | 216320_x_at | -0.1050 | 0.5147 | |
| GSE53622 | MST1 | 4485 | 119249 | 0.0375 | 0.7928 | |
| GSE53624 | MST1 | 4485 | 119249 | -0.3233 | 0.0020 | |
| GSE63941 | MST1 | 4485 | 216320_x_at | -0.1687 | 0.5783 | |
| GSE77861 | MST1 | 4485 | 205614_x_at | -0.3122 | 0.0337 | |
| GSE97050 | MST1 | A_21_P0010519 | -0.2452 | 0.3727 | ||
| SRP064894 | MST1 | 4485 | RNAseq | 0.1300 | 0.5034 | |
| SRP133303 | MST1 | 4485 | RNAseq | -0.5502 | 0.0212 | |
| SRP159526 | MST1 | 4485 | RNAseq | 0.0600 | 0.8809 | |
| SRP193095 | MST1 | 4485 | RNAseq | -0.5187 | 0.0160 | |
| SRP219564 | MST1 | 4485 | RNAseq | -0.1308 | 0.8154 | |
| TCGA | MST1 | 4485 | RNAseq | -0.2935 | 0.1122 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MST1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MST1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MST1 | 4485 | 0 | 18 | 12 | |
| GSE20123 | MST1 | 4485 | 0 | 19 | 11 | |
| GSE43470 | MST1 | 4485 | 0 | 18 | 25 | |
| GSE46452 | MST1 | 4485 | 2 | 16 | 41 | |
| GSE47630 | MST1 | 4485 | 1 | 24 | 15 | |
| GSE54993 | MST1 | 4485 | 6 | 2 | 62 | |
| GSE54994 | MST1 | 4485 | 0 | 36 | 17 | |
| GSE60625 | MST1 | 4485 | 5 | 0 | 6 | |
| GSE74703 | MST1 | 4485 | 0 | 14 | 22 | |
| GSE74704 | MST1 | 4485 | 0 | 12 | 8 | |
| TCGA | MST1 | 4485 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of MST1:
Generating mutation plots.
Highly correlated genes for MST1:
Showing top 20/245 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MST1 | TNNI2 | 0.775009 | 3 | 0 | 3 |
| MST1 | FAAH2 | 0.685037 | 4 | 0 | 3 |
| MST1 | CNGB1 | 0.674088 | 4 | 0 | 4 |
| MST1 | ING5 | 0.673566 | 4 | 0 | 3 |
| MST1 | ZNF519 | 0.659541 | 4 | 0 | 3 |
| MST1 | ARMC7 | 0.657188 | 4 | 0 | 3 |
| MST1 | CCDC130 | 0.656088 | 6 | 0 | 4 |
| MST1 | SYTL1 | 0.651542 | 3 | 0 | 3 |
| MST1 | PABPC1 | 0.649765 | 5 | 0 | 4 |
| MST1 | RAD54L2 | 0.647602 | 4 | 0 | 3 |
| MST1 | CELF3 | 0.647103 | 5 | 0 | 4 |
| MST1 | ZNF30 | 0.646501 | 3 | 0 | 3 |
| MST1 | SMG5 | 0.645612 | 3 | 0 | 3 |
| MST1 | PAX8 | 0.644244 | 5 | 0 | 3 |
| MST1 | ZBTB42 | 0.64408 | 3 | 0 | 3 |
| MST1 | PPIP5K1 | 0.640818 | 3 | 0 | 3 |
| MST1 | TOP3B | 0.639999 | 3 | 0 | 3 |
| MST1 | ZNF500 | 0.639355 | 6 | 0 | 4 |
| MST1 | LENG9 | 0.637103 | 3 | 0 | 3 |
| MST1 | ZDHHC19 | 0.636121 | 3 | 0 | 3 |
For details and further investigation, click here
