| Full name: troponin I2, fast skeletal type | Alias Symbol: FSSV|DA2B | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 7136 | HGNC ID: HGNC:11946 | Ensembl Gene: ENSG00000130598 | OMIM ID: 191043 |
| Drug and gene relationship at DGIdb | |||
Expression of TNNI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNNI2 | 7136 | 206393_at | 0.5882 | 0.6272 | |
| GSE20347 | TNNI2 | 7136 | 206393_at | -0.2345 | 0.0715 | |
| GSE23400 | TNNI2 | 7136 | 206393_at | 0.0037 | 0.9577 | |
| GSE26886 | TNNI2 | 7136 | 206393_at | 0.3167 | 0.2677 | |
| GSE29001 | TNNI2 | 7136 | 206393_at | -0.4196 | 0.0605 | |
| GSE38129 | TNNI2 | 7136 | 206393_at | -0.1550 | 0.3043 | |
| GSE45670 | TNNI2 | 7136 | 206393_at | -0.4962 | 0.0028 | |
| GSE53622 | TNNI2 | 7136 | 64719 | -0.0437 | 0.5764 | |
| GSE53624 | TNNI2 | 7136 | 64719 | -0.0990 | 0.2578 | |
| GSE63941 | TNNI2 | 7136 | 206393_at | 0.5129 | 0.0296 | |
| GSE77861 | TNNI2 | 7136 | 206393_at | -0.2426 | 0.1015 | |
| GSE97050 | TNNI2 | 7136 | A_23_P24784 | -0.2416 | 0.5101 | |
| SRP064894 | TNNI2 | 7136 | RNAseq | -1.0935 | 0.0027 | |
| SRP133303 | TNNI2 | 7136 | RNAseq | -1.4524 | 0.0002 | |
| SRP159526 | TNNI2 | 7136 | RNAseq | -0.9403 | 0.2815 | |
| SRP219564 | TNNI2 | 7136 | RNAseq | -1.0990 | 0.1727 | |
| TCGA | TNNI2 | 7136 | RNAseq | 0.7962 | 0.1077 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TNNI2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNNI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNNI2 | 7136 | 1 | 11 | 18 | |
| GSE20123 | TNNI2 | 7136 | 1 | 12 | 17 | |
| GSE43470 | TNNI2 | 7136 | 1 | 9 | 33 | |
| GSE46452 | TNNI2 | 7136 | 7 | 8 | 44 | |
| GSE47630 | TNNI2 | 7136 | 4 | 12 | 24 | |
| GSE54993 | TNNI2 | 7136 | 3 | 1 | 66 | |
| GSE54994 | TNNI2 | 7136 | 1 | 12 | 40 | |
| GSE60625 | TNNI2 | 7136 | 0 | 0 | 11 | |
| GSE74703 | TNNI2 | 7136 | 1 | 7 | 28 | |
| GSE74704 | TNNI2 | 7136 | 0 | 8 | 12 | |
| TCGA | TNNI2 | 7136 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 119; Total Number of normals: 342.
Somatic mutations of TNNI2:
Generating mutation plots.
Highly correlated genes for TNNI2:
Showing top 20/428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNNI2 | GRIK4 | 0.8258 | 3 | 0 | 3 |
| TNNI2 | LRIT1 | 0.808168 | 3 | 0 | 3 |
| TNNI2 | STRC | 0.80689 | 3 | 0 | 3 |
| TNNI2 | GLI4 | 0.789805 | 3 | 0 | 3 |
| TNNI2 | TTC12 | 0.782992 | 3 | 0 | 3 |
| TNNI2 | DCDC1 | 0.781739 | 3 | 0 | 3 |
| TNNI2 | VEPH1 | 0.780541 | 3 | 0 | 3 |
| TNNI2 | SYT8 | 0.779009 | 7 | 0 | 6 |
| TNNI2 | OR2T27 | 0.776348 | 3 | 0 | 3 |
| TNNI2 | MST1 | 0.775009 | 3 | 0 | 3 |
| TNNI2 | PLA2G2C | 0.772642 | 3 | 0 | 3 |
| TNNI2 | B3GNT8 | 0.764057 | 3 | 0 | 3 |
| TNNI2 | PRR15 | 0.762792 | 3 | 0 | 3 |
| TNNI2 | TMEM179 | 0.761033 | 3 | 0 | 3 |
| TNNI2 | UMODL1 | 0.760977 | 3 | 0 | 3 |
| TNNI2 | ZNF527 | 0.760719 | 3 | 0 | 3 |
| TNNI2 | KIRREL2 | 0.756876 | 4 | 0 | 4 |
| TNNI2 | ZNF497 | 0.756546 | 3 | 0 | 3 |
| TNNI2 | PRG3 | 0.751353 | 3 | 0 | 3 |
| TNNI2 | C1QL2 | 0.749467 | 3 | 0 | 3 |
For details and further investigation, click here
