| Full name: RAD54 like 2 | Alias Symbol: KIAA0809|SRISNF2L|ARIP4 | ||
| Type: protein-coding gene | Cytoband: 3p21.2 | ||
| Entrez ID: 23132 | HGNC ID: HGNC:29123 | Ensembl Gene: ENSG00000164080 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RAD54L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAD54L2 | 23132 | 213205_s_at | 0.5162 | 0.1219 | |
| GSE20347 | RAD54L2 | 23132 | 213205_s_at | 0.1863 | 0.0659 | |
| GSE23400 | RAD54L2 | 23132 | 213205_s_at | -0.0618 | 0.2192 | |
| GSE26886 | RAD54L2 | 23132 | 226624_at | -0.2253 | 0.2040 | |
| GSE29001 | RAD54L2 | 23132 | 213205_s_at | -0.0041 | 0.9836 | |
| GSE38129 | RAD54L2 | 23132 | 213205_s_at | -0.0522 | 0.5992 | |
| GSE45670 | RAD54L2 | 23132 | 226624_at | -0.0484 | 0.6571 | |
| GSE53622 | RAD54L2 | 23132 | 62601 | -0.0088 | 0.8893 | |
| GSE53624 | RAD54L2 | 23132 | 62601 | 0.0837 | 0.5596 | |
| GSE63941 | RAD54L2 | 23132 | 226624_at | -0.4448 | 0.0419 | |
| GSE77861 | RAD54L2 | 23132 | 213205_s_at | 0.1273 | 0.4883 | |
| GSE97050 | RAD54L2 | 23132 | A_23_P18205 | 0.0197 | 0.9346 | |
| SRP007169 | RAD54L2 | 23132 | RNAseq | 1.0980 | 0.0152 | |
| SRP008496 | RAD54L2 | 23132 | RNAseq | 1.1713 | 0.0001 | |
| SRP064894 | RAD54L2 | 23132 | RNAseq | -0.0789 | 0.6879 | |
| SRP133303 | RAD54L2 | 23132 | RNAseq | -0.1008 | 0.3418 | |
| SRP159526 | RAD54L2 | 23132 | RNAseq | 0.3776 | 0.1185 | |
| SRP193095 | RAD54L2 | 23132 | RNAseq | 0.2990 | 0.0038 | |
| SRP219564 | RAD54L2 | 23132 | RNAseq | -0.0487 | 0.8857 | |
| TCGA | RAD54L2 | 23132 | RNAseq | -0.1738 | 0.0042 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RAD54L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAD54L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAD54L2 | 23132 | 0 | 18 | 12 | |
| GSE20123 | RAD54L2 | 23132 | 0 | 19 | 11 | |
| GSE43470 | RAD54L2 | 23132 | 0 | 18 | 25 | |
| GSE46452 | RAD54L2 | 23132 | 2 | 16 | 41 | |
| GSE47630 | RAD54L2 | 23132 | 1 | 24 | 15 | |
| GSE54993 | RAD54L2 | 23132 | 6 | 2 | 62 | |
| GSE54994 | RAD54L2 | 23132 | 0 | 35 | 18 | |
| GSE60625 | RAD54L2 | 23132 | 5 | 0 | 6 | |
| GSE74703 | RAD54L2 | 23132 | 0 | 14 | 22 | |
| GSE74704 | RAD54L2 | 23132 | 0 | 12 | 8 | |
| TCGA | RAD54L2 | 23132 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 236; Total Number of normals: 238.
Somatic mutations of RAD54L2:
Generating mutation plots.
Highly correlated genes for RAD54L2:
Showing top 20/103 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAD54L2 | ING5 | 0.708634 | 3 | 0 | 3 |
| RAD54L2 | RHBDD3 | 0.695034 | 3 | 0 | 3 |
| RAD54L2 | SPEF1 | 0.690467 | 3 | 0 | 3 |
| RAD54L2 | GGT7 | 0.689063 | 3 | 0 | 3 |
| RAD54L2 | STK11 | 0.686626 | 4 | 0 | 3 |
| RAD54L2 | DNMT3B | 0.662845 | 3 | 0 | 3 |
| RAD54L2 | MST1 | 0.647602 | 4 | 0 | 3 |
| RAD54L2 | YEATS2 | 0.643518 | 4 | 0 | 3 |
| RAD54L2 | PHC3 | 0.625671 | 3 | 0 | 3 |
| RAD54L2 | NKX2-2 | 0.623124 | 3 | 0 | 3 |
| RAD54L2 | KLHL35 | 0.622979 | 3 | 0 | 3 |
| RAD54L2 | GABRB1 | 0.622142 | 3 | 0 | 3 |
| RAD54L2 | CLDN23 | 0.620715 | 3 | 0 | 3 |
| RAD54L2 | PRPF3 | 0.615996 | 4 | 0 | 3 |
| RAD54L2 | NR2E1 | 0.614722 | 5 | 0 | 4 |
| RAD54L2 | HAUS5 | 0.61086 | 4 | 0 | 4 |
| RAD54L2 | ANXA10 | 0.609428 | 3 | 0 | 3 |
| RAD54L2 | TNK2 | 0.599676 | 5 | 0 | 3 |
| RAD54L2 | SPATA2L | 0.599432 | 4 | 0 | 3 |
| RAD54L2 | PML | 0.599398 | 5 | 0 | 4 |
For details and further investigation, click here
