| Full name: coiled-coil domain containing 130 | Alias Symbol: MGC10471 | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 81576 | HGNC ID: HGNC:28118 | Ensembl Gene: ENSG00000104957 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCDC130:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC130 | 81576 | 208094_s_at | 0.1431 | 0.8089 | |
| GSE20347 | CCDC130 | 81576 | 208094_s_at | 0.0527 | 0.6982 | |
| GSE23400 | CCDC130 | 81576 | 208094_s_at | 0.1945 | 0.0011 | |
| GSE26886 | CCDC130 | 81576 | 208094_s_at | 0.4353 | 0.0014 | |
| GSE29001 | CCDC130 | 81576 | 208094_s_at | -0.0112 | 0.9639 | |
| GSE38129 | CCDC130 | 81576 | 208094_s_at | 0.0288 | 0.7795 | |
| GSE45670 | CCDC130 | 81576 | 208094_s_at | 0.0478 | 0.7005 | |
| GSE53622 | CCDC130 | 81576 | 44179 | 0.0868 | 0.0433 | |
| GSE53624 | CCDC130 | 81576 | 44179 | 0.1229 | 0.0264 | |
| GSE63941 | CCDC130 | 81576 | 208094_s_at | -0.1667 | 0.6695 | |
| GSE77861 | CCDC130 | 81576 | 208094_s_at | 0.1594 | 0.2046 | |
| GSE97050 | CCDC130 | 81576 | A_23_P101461 | 0.1054 | 0.6505 | |
| SRP007169 | CCDC130 | 81576 | RNAseq | -0.7088 | 0.1729 | |
| SRP008496 | CCDC130 | 81576 | RNAseq | -0.6469 | 0.0313 | |
| SRP064894 | CCDC130 | 81576 | RNAseq | 0.6162 | 0.0108 | |
| SRP133303 | CCDC130 | 81576 | RNAseq | -0.1201 | 0.4008 | |
| SRP159526 | CCDC130 | 81576 | RNAseq | 0.0037 | 0.9924 | |
| SRP193095 | CCDC130 | 81576 | RNAseq | 0.2365 | 0.0510 | |
| SRP219564 | CCDC130 | 81576 | RNAseq | 0.2767 | 0.4655 | |
| TCGA | CCDC130 | 81576 | RNAseq | 0.0189 | 0.7524 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC130 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC130:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC130 | 81576 | 4 | 2 | 24 | |
| GSE20123 | CCDC130 | 81576 | 3 | 1 | 26 | |
| GSE43470 | CCDC130 | 81576 | 2 | 6 | 35 | |
| GSE46452 | CCDC130 | 81576 | 47 | 1 | 11 | |
| GSE47630 | CCDC130 | 81576 | 4 | 7 | 29 | |
| GSE54993 | CCDC130 | 81576 | 15 | 4 | 51 | |
| GSE54994 | CCDC130 | 81576 | 6 | 13 | 34 | |
| GSE60625 | CCDC130 | 81576 | 9 | 0 | 2 | |
| GSE74703 | CCDC130 | 81576 | 2 | 4 | 30 | |
| GSE74704 | CCDC130 | 81576 | 0 | 1 | 19 | |
| TCGA | CCDC130 | 81576 | 21 | 11 | 64 |
Total number of gains: 113; Total number of losses: 50; Total Number of normals: 325.
Somatic mutations of CCDC130:
Generating mutation plots.
Highly correlated genes for CCDC130:
Showing top 20/202 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC130 | NPPC | 0.754832 | 3 | 0 | 3 |
| CCDC130 | RAB40B | 0.744919 | 3 | 0 | 3 |
| CCDC130 | TMUB1 | 0.727334 | 4 | 0 | 4 |
| CCDC130 | SIPA1L1 | 0.725625 | 3 | 0 | 3 |
| CCDC130 | PYGO2 | 0.725017 | 3 | 0 | 3 |
| CCDC130 | USHBP1 | 0.712006 | 3 | 0 | 3 |
| CCDC130 | FAM71E2 | 0.705175 | 3 | 0 | 3 |
| CCDC130 | C19orf53 | 0.698515 | 5 | 0 | 5 |
| CCDC130 | PTPRCAP | 0.697315 | 3 | 0 | 3 |
| CCDC130 | SLC27A5 | 0.696343 | 3 | 0 | 3 |
| CCDC130 | CDC42EP2 | 0.692788 | 4 | 0 | 4 |
| CCDC130 | ADRA1B | 0.692485 | 3 | 0 | 3 |
| CCDC130 | PHKA2 | 0.687456 | 4 | 0 | 3 |
| CCDC130 | COL24A1 | 0.683366 | 3 | 0 | 3 |
| CCDC130 | SYNGAP1 | 0.680303 | 3 | 0 | 3 |
| CCDC130 | ZNF182 | 0.678317 | 4 | 0 | 4 |
| CCDC130 | RANBP3 | 0.677134 | 8 | 0 | 8 |
| CCDC130 | PLEC | 0.67575 | 4 | 0 | 3 |
| CCDC130 | SIGIRR | 0.672874 | 5 | 0 | 4 |
| CCDC130 | NFKBIB | 0.671872 | 4 | 0 | 4 |
For details and further investigation, click here
