| Full name: diphosphoinositol pentakisphosphate kinase 1 | Alias Symbol: KIAA0377|IPS1|VIP1 | ||
| Type: protein-coding gene | Cytoband: 15q15.3 | ||
| Entrez ID: 9677 | HGNC ID: HGNC:29023 | Ensembl Gene: ENSG00000168781 | OMIM ID: 610979 |
| Drug and gene relationship at DGIdb | |||
Expression of PPIP5K1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPIP5K1 | 9677 | 204578_at | -0.0608 | 0.8087 | |
| GSE20347 | PPIP5K1 | 9677 | 204578_at | 0.0322 | 0.7694 | |
| GSE23400 | PPIP5K1 | 9677 | 204578_at | 0.0067 | 0.9076 | |
| GSE26886 | PPIP5K1 | 9677 | 204578_at | -0.0822 | 0.6577 | |
| GSE29001 | PPIP5K1 | 9677 | 204578_at | -0.2740 | 0.1840 | |
| GSE38129 | PPIP5K1 | 9677 | 204578_at | 0.1100 | 0.2422 | |
| GSE45670 | PPIP5K1 | 9677 | 204578_at | 0.1623 | 0.2713 | |
| GSE53622 | PPIP5K1 | 9677 | 105823 | -0.0454 | 0.4783 | |
| GSE53624 | PPIP5K1 | 9677 | 105823 | 0.0458 | 0.4828 | |
| GSE63941 | PPIP5K1 | 9677 | 1555255_a_at | 1.1842 | 0.0006 | |
| GSE77861 | PPIP5K1 | 9677 | 204578_at | 0.2054 | 0.2723 | |
| GSE97050 | PPIP5K1 | 9677 | A_33_P3340180 | -0.0900 | 0.6805 | |
| SRP007169 | PPIP5K1 | 9677 | RNAseq | 0.2646 | 0.5269 | |
| SRP008496 | PPIP5K1 | 9677 | RNAseq | 0.0338 | 0.9042 | |
| SRP064894 | PPIP5K1 | 9677 | RNAseq | -0.2778 | 0.2067 | |
| SRP133303 | PPIP5K1 | 9677 | RNAseq | -0.0971 | 0.6568 | |
| SRP159526 | PPIP5K1 | 9677 | RNAseq | -0.6410 | 0.0609 | |
| SRP193095 | PPIP5K1 | 9677 | RNAseq | -0.1098 | 0.3445 | |
| SRP219564 | PPIP5K1 | 9677 | RNAseq | -0.6598 | 0.0393 | |
| TCGA | PPIP5K1 | 9677 | RNAseq | -0.1309 | 0.0111 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PPIP5K1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPIP5K1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPIP5K1 | 9677 | 3 | 4 | 23 | |
| GSE20123 | PPIP5K1 | 9677 | 3 | 5 | 22 | |
| GSE43470 | PPIP5K1 | 9677 | 3 | 5 | 35 | |
| GSE46452 | PPIP5K1 | 9677 | 3 | 7 | 49 | |
| GSE47630 | PPIP5K1 | 9677 | 8 | 10 | 22 | |
| GSE54993 | PPIP5K1 | 9677 | 4 | 6 | 60 | |
| GSE54994 | PPIP5K1 | 9677 | 5 | 7 | 41 | |
| GSE60625 | PPIP5K1 | 9677 | 4 | 0 | 7 | |
| GSE74703 | PPIP5K1 | 9677 | 3 | 3 | 30 | |
| GSE74704 | PPIP5K1 | 9677 | 2 | 2 | 16 | |
| TCGA | PPIP5K1 | 9677 | 12 | 17 | 67 |
Total number of gains: 50; Total number of losses: 66; Total Number of normals: 372.
Somatic mutations of PPIP5K1:
Generating mutation plots.
Highly correlated genes for PPIP5K1:
Showing top 20/47 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPIP5K1 | EPB41L4B | 0.698138 | 3 | 0 | 3 |
| PPIP5K1 | EDC3 | 0.685237 | 3 | 0 | 3 |
| PPIP5K1 | E2F1 | 0.679971 | 3 | 0 | 3 |
| PPIP5K1 | EML2 | 0.677108 | 4 | 0 | 4 |
| PPIP5K1 | CCDC22 | 0.674127 | 3 | 0 | 3 |
| PPIP5K1 | ZNF763 | 0.657192 | 3 | 0 | 3 |
| PPIP5K1 | MST1 | 0.640818 | 3 | 0 | 3 |
| PPIP5K1 | POMC | 0.634194 | 3 | 0 | 3 |
| PPIP5K1 | LRRC4 | 0.631046 | 3 | 0 | 3 |
| PPIP5K1 | HSF4 | 0.627998 | 3 | 0 | 3 |
| PPIP5K1 | CDC6 | 0.613153 | 3 | 0 | 3 |
| PPIP5K1 | TNFAIP8L1 | 0.612392 | 3 | 0 | 3 |
| PPIP5K1 | TSPAN33 | 0.610581 | 3 | 0 | 3 |
| PPIP5K1 | CADM4 | 0.60811 | 4 | 0 | 3 |
| PPIP5K1 | ZNF692 | 0.60759 | 5 | 0 | 4 |
| PPIP5K1 | HOOK2 | 0.606823 | 3 | 0 | 3 |
| PPIP5K1 | KAT6A | 0.605518 | 3 | 0 | 3 |
| PPIP5K1 | KIAA1671 | 0.598351 | 3 | 0 | 3 |
| PPIP5K1 | BCAT2 | 0.596524 | 3 | 0 | 3 |
| PPIP5K1 | KDF1 | 0.59625 | 3 | 0 | 3 |
For details and further investigation, click here
