| Full name: zinc finger protein 519 | Alias Symbol: HsT2362|FLJ36809 | ||
| Type: protein-coding gene | Cytoband: 18p11.21 | ||
| Entrez ID: 162655 | HGNC ID: HGNC:30574 | Ensembl Gene: ENSG00000175322 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNF519:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF519 | 162655 | 1568873_at | 0.3905 | 0.4764 | |
| GSE26886 | ZNF519 | 162655 | 1564190_x_at | -0.8746 | 0.0004 | |
| GSE45670 | ZNF519 | 162655 | 1568873_at | -0.2476 | 0.2408 | |
| GSE53622 | ZNF519 | 162655 | 66706 | -0.0930 | 0.4832 | |
| GSE53624 | ZNF519 | 162655 | 66706 | -0.0597 | 0.5762 | |
| GSE63941 | ZNF519 | 162655 | 1568873_at | 0.9360 | 0.0732 | |
| GSE77861 | ZNF519 | 162655 | 1564190_x_at | -0.2509 | 0.0504 | |
| GSE97050 | ZNF519 | 162655 | A_23_P328766 | 0.1181 | 0.7114 | |
| SRP007169 | ZNF519 | 162655 | RNAseq | -0.3263 | 0.4440 | |
| SRP008496 | ZNF519 | 162655 | RNAseq | -0.4260 | 0.2187 | |
| SRP064894 | ZNF519 | 162655 | RNAseq | -0.7142 | 0.0062 | |
| SRP133303 | ZNF519 | 162655 | RNAseq | -0.1177 | 0.5636 | |
| SRP159526 | ZNF519 | 162655 | RNAseq | 0.2144 | 0.6320 | |
| SRP193095 | ZNF519 | 162655 | RNAseq | -0.1004 | 0.5538 | |
| SRP219564 | ZNF519 | 162655 | RNAseq | -0.8112 | 0.0877 | |
| TCGA | ZNF519 | 162655 | RNAseq | 0.4380 | 0.0089 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF519 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF519:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF519 | 162655 | 4 | 3 | 23 | |
| GSE20123 | ZNF519 | 162655 | 4 | 3 | 23 | |
| GSE43470 | ZNF519 | 162655 | 0 | 6 | 37 | |
| GSE46452 | ZNF519 | 162655 | 3 | 21 | 35 | |
| GSE47630 | ZNF519 | 162655 | 7 | 17 | 16 | |
| GSE54993 | ZNF519 | 162655 | 6 | 2 | 62 | |
| GSE54994 | ZNF519 | 162655 | 9 | 8 | 36 | |
| GSE60625 | ZNF519 | 162655 | 0 | 4 | 7 | |
| GSE74703 | ZNF519 | 162655 | 0 | 4 | 32 | |
| GSE74704 | ZNF519 | 162655 | 3 | 2 | 15 | |
| TCGA | ZNF519 | 162655 | 28 | 23 | 45 |
Total number of gains: 64; Total number of losses: 93; Total Number of normals: 331.
Somatic mutations of ZNF519:
Generating mutation plots.
Highly correlated genes for ZNF519:
Showing top 20/98 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF519 | SLC35C1 | 0.752679 | 3 | 0 | 3 |
| ZNF519 | SLC23A3 | 0.735348 | 3 | 0 | 3 |
| ZNF519 | SYBU | 0.712654 | 3 | 0 | 3 |
| ZNF519 | ANKAR | 0.705624 | 3 | 0 | 3 |
| ZNF519 | TRAIP | 0.701043 | 3 | 0 | 3 |
| ZNF519 | ERBB2 | 0.698029 | 3 | 0 | 3 |
| ZNF519 | MAST4 | 0.692045 | 3 | 0 | 3 |
| ZNF519 | CHTF8 | 0.683513 | 3 | 0 | 3 |
| ZNF519 | KSR1 | 0.680394 | 3 | 0 | 3 |
| ZNF519 | POLQ | 0.6783 | 4 | 0 | 3 |
| ZNF519 | PHLDB3 | 0.673108 | 3 | 0 | 3 |
| ZNF519 | DBF4B | 0.670723 | 3 | 0 | 3 |
| ZNF519 | RBM47 | 0.667986 | 3 | 0 | 3 |
| ZNF519 | GCHFR | 0.665152 | 3 | 0 | 3 |
| ZNF519 | MACC1 | 0.662945 | 3 | 0 | 3 |
| ZNF519 | MAPK13 | 0.660168 | 4 | 0 | 4 |
| ZNF519 | MST1 | 0.659541 | 4 | 0 | 3 |
| ZNF519 | SFTPD | 0.658905 | 3 | 0 | 3 |
| ZNF519 | WWC1 | 0.656028 | 3 | 0 | 3 |
| ZNF519 | ESPL1 | 0.65478 | 4 | 0 | 4 |
For details and further investigation, click here
