| Full name: synaptotagmin like 1 | Alias Symbol: SLP1|JFC1|FLJ14996|exophilin-7 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 84958 | HGNC ID: HGNC:15584 | Ensembl Gene: ENSG00000142765 | OMIM ID: 608042 |
| Drug and gene relationship at DGIdb | |||
Expression of SYTL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYTL1 | 84958 | 227134_at | -0.5128 | 0.3212 | |
| GSE26886 | SYTL1 | 84958 | 227134_at | -1.4340 | 0.0000 | |
| GSE45670 | SYTL1 | 84958 | 227134_at | -0.4795 | 0.0471 | |
| GSE53622 | SYTL1 | 84958 | 49468 | -1.0288 | 0.0000 | |
| GSE53624 | SYTL1 | 84958 | 49468 | -1.4004 | 0.0000 | |
| GSE63941 | SYTL1 | 84958 | 227134_at | 3.6563 | 0.0000 | |
| GSE77861 | SYTL1 | 84958 | 227134_at | -1.0612 | 0.0108 | |
| GSE97050 | SYTL1 | 84958 | A_33_P3266744 | 0.4554 | 0.5274 | |
| SRP007169 | SYTL1 | 84958 | RNAseq | -2.0453 | 0.0000 | |
| SRP008496 | SYTL1 | 84958 | RNAseq | -1.8026 | 0.0000 | |
| SRP064894 | SYTL1 | 84958 | RNAseq | -1.0165 | 0.0008 | |
| SRP133303 | SYTL1 | 84958 | RNAseq | -1.0743 | 0.0003 | |
| SRP159526 | SYTL1 | 84958 | RNAseq | -1.3676 | 0.0002 | |
| SRP193095 | SYTL1 | 84958 | RNAseq | -1.1288 | 0.0000 | |
| SRP219564 | SYTL1 | 84958 | RNAseq | -0.9253 | 0.2977 | |
| TCGA | SYTL1 | 84958 | RNAseq | 0.1017 | 0.3601 |
Upregulated datasets: 1; Downregulated datasets: 10.
Survival by SYTL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYTL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYTL1 | 84958 | 0 | 6 | 24 | |
| GSE20123 | SYTL1 | 84958 | 0 | 5 | 25 | |
| GSE43470 | SYTL1 | 84958 | 3 | 6 | 34 | |
| GSE46452 | SYTL1 | 84958 | 5 | 1 | 53 | |
| GSE47630 | SYTL1 | 84958 | 8 | 3 | 29 | |
| GSE54993 | SYTL1 | 84958 | 2 | 1 | 67 | |
| GSE54994 | SYTL1 | 84958 | 10 | 4 | 39 | |
| GSE60625 | SYTL1 | 84958 | 0 | 0 | 11 | |
| GSE74703 | SYTL1 | 84958 | 2 | 4 | 30 | |
| GSE74704 | SYTL1 | 84958 | 0 | 0 | 20 | |
| TCGA | SYTL1 | 84958 | 11 | 24 | 61 |
Total number of gains: 41; Total number of losses: 54; Total Number of normals: 393.
Somatic mutations of SYTL1:
Generating mutation plots.
Highly correlated genes for SYTL1:
Showing top 20/1259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYTL1 | NIPAL1 | 0.848417 | 3 | 0 | 3 |
| SYTL1 | EPS8L2 | 0.81749 | 6 | 0 | 6 |
| SYTL1 | DENND2D | 0.792552 | 7 | 0 | 7 |
| SYTL1 | SLC37A1 | 0.790045 | 6 | 0 | 6 |
| SYTL1 | RAB25 | 0.78255 | 9 | 0 | 9 |
| SYTL1 | TST | 0.780109 | 5 | 0 | 5 |
| SYTL1 | EVPL | 0.779674 | 8 | 0 | 8 |
| SYTL1 | ARHGAP27 | 0.778127 | 9 | 0 | 9 |
| SYTL1 | DGKA | 0.774183 | 9 | 0 | 9 |
| SYTL1 | LTA4H | 0.768821 | 3 | 0 | 3 |
| SYTL1 | TECR | 0.767932 | 9 | 0 | 8 |
| SYTL1 | PADI1 | 0.766153 | 5 | 0 | 5 |
| SYTL1 | FAM83G | 0.765141 | 3 | 0 | 3 |
| SYTL1 | IKZF2 | 0.762908 | 7 | 0 | 7 |
| SYTL1 | UPK3B | 0.757656 | 3 | 0 | 3 |
| SYTL1 | ARHGAP32 | 0.756458 | 7 | 0 | 7 |
| SYTL1 | VAV3 | 0.755566 | 6 | 0 | 6 |
| SYTL1 | CNKSR1 | 0.752852 | 6 | 0 | 6 |
| SYTL1 | RARG | 0.751836 | 8 | 0 | 8 |
| SYTL1 | RIPK4 | 0.75159 | 5 | 0 | 5 |
For details and further investigation, click here
