| Full name: myotubularin related protein 12 | Alias Symbol: 3-PAP|FLJ20476|KIAA1682|3PAP | ||
| Type: protein-coding gene | Cytoband: 5p13.3 | ||
| Entrez ID: 54545 | HGNC ID: HGNC:18191 | Ensembl Gene: ENSG00000150712 | OMIM ID: 606501 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MTMR12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTMR12 | 54545 | 225232_at | -0.2272 | 0.7498 | |
| GSE20347 | MTMR12 | 54545 | 220953_s_at | 0.1077 | 0.4159 | |
| GSE23400 | MTMR12 | 54545 | 220953_s_at | -0.1214 | 0.0066 | |
| GSE26886 | MTMR12 | 54545 | 225232_at | -0.6183 | 0.0049 | |
| GSE29001 | MTMR12 | 54545 | 220953_s_at | -0.2445 | 0.2472 | |
| GSE38129 | MTMR12 | 54545 | 220953_s_at | 0.0223 | 0.8681 | |
| GSE45670 | MTMR12 | 54545 | 225232_at | -0.3611 | 0.0205 | |
| GSE53622 | MTMR12 | 54545 | 98045 | -0.0518 | 0.5380 | |
| GSE53624 | MTMR12 | 54545 | 98045 | -0.3497 | 0.0000 | |
| GSE63941 | MTMR12 | 54545 | 225232_at | 0.4355 | 0.2465 | |
| GSE77861 | MTMR12 | 54545 | 225232_at | 0.1111 | 0.7700 | |
| GSE97050 | MTMR12 | 54545 | A_24_P354615 | -0.4243 | 0.2128 | |
| SRP007169 | MTMR12 | 54545 | RNAseq | -0.2628 | 0.5244 | |
| SRP008496 | MTMR12 | 54545 | RNAseq | -0.1689 | 0.5057 | |
| SRP064894 | MTMR12 | 54545 | RNAseq | -0.8217 | 0.0000 | |
| SRP133303 | MTMR12 | 54545 | RNAseq | -0.3740 | 0.0116 | |
| SRP159526 | MTMR12 | 54545 | RNAseq | 0.3167 | 0.2951 | |
| SRP193095 | MTMR12 | 54545 | RNAseq | -0.3747 | 0.0001 | |
| SRP219564 | MTMR12 | 54545 | RNAseq | -0.6115 | 0.1155 | |
| TCGA | MTMR12 | 54545 | RNAseq | -0.2641 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTMR12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTMR12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTMR12 | 54545 | 11 | 0 | 19 | |
| GSE20123 | MTMR12 | 54545 | 11 | 0 | 19 | |
| GSE43470 | MTMR12 | 54545 | 15 | 3 | 25 | |
| GSE46452 | MTMR12 | 54545 | 6 | 21 | 32 | |
| GSE47630 | MTMR12 | 54545 | 6 | 12 | 22 | |
| GSE54993 | MTMR12 | 54545 | 5 | 4 | 61 | |
| GSE54994 | MTMR12 | 54545 | 27 | 2 | 24 | |
| GSE60625 | MTMR12 | 54545 | 0 | 0 | 11 | |
| GSE74703 | MTMR12 | 54545 | 12 | 2 | 22 | |
| GSE74704 | MTMR12 | 54545 | 10 | 0 | 10 | |
| TCGA | MTMR12 | 54545 | 51 | 6 | 39 |
Total number of gains: 154; Total number of losses: 50; Total Number of normals: 284.
Somatic mutations of MTMR12:
Generating mutation plots.
Highly correlated genes for MTMR12:
Showing top 20/319 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTMR12 | RSBN1 | 0.847298 | 3 | 0 | 3 |
| MTMR12 | UXT | 0.832609 | 3 | 0 | 3 |
| MTMR12 | TUBE1 | 0.786264 | 3 | 0 | 3 |
| MTMR12 | NCOR1 | 0.783447 | 3 | 0 | 3 |
| MTMR12 | ZNF506 | 0.778263 | 3 | 0 | 3 |
| MTMR12 | ZNF844 | 0.77211 | 3 | 0 | 3 |
| MTMR12 | CLDND1 | 0.757943 | 3 | 0 | 3 |
| MTMR12 | UHRF1BP1L | 0.756847 | 3 | 0 | 3 |
| MTMR12 | FAN1 | 0.756249 | 3 | 0 | 3 |
| MTMR12 | ZNF564 | 0.748128 | 3 | 0 | 3 |
| MTMR12 | MTRF1L | 0.745959 | 3 | 0 | 3 |
| MTMR12 | TRAPPC2 | 0.744439 | 4 | 0 | 4 |
| MTMR12 | UPF3B | 0.733847 | 3 | 0 | 3 |
| MTMR12 | PARG | 0.728411 | 3 | 0 | 3 |
| MTMR12 | NHS | 0.72157 | 4 | 0 | 3 |
| MTMR12 | DOCK7 | 0.721074 | 3 | 0 | 3 |
| MTMR12 | SRGAP1 | 0.720143 | 3 | 0 | 3 |
| MTMR12 | ATXN7L3B | 0.719615 | 3 | 0 | 3 |
| MTMR12 | PPM1L | 0.719565 | 4 | 0 | 3 |
| MTMR12 | C1GALT1C1 | 0.714908 | 3 | 0 | 3 |
For details and further investigation, click here
