| Full name: ataxin 7 like 3B | Alias Symbol: lnc-SCA7 | ||
| Type: protein-coding gene | Cytoband: 12q21.1 | ||
| Entrez ID: 552889 | HGNC ID: HGNC:37931 | Ensembl Gene: ENSG00000253719 | OMIM ID: 615579 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ATXN7L3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATXN7L3B | 552889 | 212114_at | 0.2291 | 0.6391 | |
| GSE20347 | ATXN7L3B | 552889 | 212114_at | 0.0811 | 0.5821 | |
| GSE23400 | ATXN7L3B | 552889 | 212114_at | 0.0818 | 0.0858 | |
| GSE26886 | ATXN7L3B | 552889 | 212114_at | -0.1976 | 0.3416 | |
| GSE29001 | ATXN7L3B | 552889 | 212114_at | 0.2170 | 0.2313 | |
| GSE38129 | ATXN7L3B | 552889 | 212114_at | 0.1009 | 0.3518 | |
| GSE45670 | ATXN7L3B | 552889 | 212114_at | 0.0908 | 0.3250 | |
| GSE53622 | ATXN7L3B | 552889 | 8732 | -0.1913 | 0.0053 | |
| GSE53624 | ATXN7L3B | 552889 | 8732 | -0.0374 | 0.5427 | |
| GSE63941 | ATXN7L3B | 552889 | 212114_at | 0.0763 | 0.8216 | |
| GSE77861 | ATXN7L3B | 552889 | 212114_at | 0.1940 | 0.2834 | |
| GSE97050 | ATXN7L3B | 552889 | A_24_P263956 | -0.2087 | 0.2990 | |
| SRP007169 | ATXN7L3B | 552889 | RNAseq | 0.5270 | 0.1179 | |
| SRP008496 | ATXN7L3B | 552889 | RNAseq | 0.7114 | 0.0001 | |
| SRP064894 | ATXN7L3B | 552889 | RNAseq | -0.2172 | 0.0867 | |
| SRP133303 | ATXN7L3B | 552889 | RNAseq | 0.0546 | 0.7099 | |
| SRP159526 | ATXN7L3B | 552889 | RNAseq | 0.5281 | 0.0319 | |
| SRP193095 | ATXN7L3B | 552889 | RNAseq | -0.3608 | 0.0157 | |
| SRP219564 | ATXN7L3B | 552889 | RNAseq | -0.0725 | 0.7051 | |
| TCGA | ATXN7L3B | 552889 | RNAseq | -0.1714 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATXN7L3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATXN7L3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATXN7L3B | 552889 | 3 | 3 | 24 | |
| GSE20123 | ATXN7L3B | 552889 | 3 | 3 | 24 | |
| GSE43470 | ATXN7L3B | 552889 | 3 | 0 | 40 | |
| GSE46452 | ATXN7L3B | 552889 | 8 | 1 | 50 | |
| GSE47630 | ATXN7L3B | 552889 | 10 | 1 | 29 | |
| GSE54993 | ATXN7L3B | 552889 | 0 | 5 | 65 | |
| GSE54994 | ATXN7L3B | 552889 | 5 | 2 | 46 | |
| GSE60625 | ATXN7L3B | 552889 | 0 | 0 | 11 | |
| GSE74703 | ATXN7L3B | 552889 | 3 | 0 | 33 | |
| GSE74704 | ATXN7L3B | 552889 | 2 | 2 | 16 | |
| TCGA | ATXN7L3B | 552889 | 16 | 14 | 66 |
Total number of gains: 53; Total number of losses: 31; Total Number of normals: 404.
Somatic mutations of ATXN7L3B:
Generating mutation plots.
Highly correlated genes for ATXN7L3B:
Showing top 20/345 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATXN7L3B | C2CD2 | 0.836059 | 3 | 0 | 3 |
| ATXN7L3B | VRK3 | 0.829729 | 3 | 0 | 3 |
| ATXN7L3B | TBL1X | 0.815559 | 3 | 0 | 3 |
| ATXN7L3B | NDUFS3 | 0.790094 | 3 | 0 | 3 |
| ATXN7L3B | NOC3L | 0.778903 | 3 | 0 | 3 |
| ATXN7L3B | HDAC6 | 0.778679 | 3 | 0 | 3 |
| ATXN7L3B | TXNDC16 | 0.77827 | 3 | 0 | 3 |
| ATXN7L3B | CTPS2 | 0.762285 | 3 | 0 | 3 |
| ATXN7L3B | WDR13 | 0.757625 | 3 | 0 | 3 |
| ATXN7L3B | SLC9A8 | 0.756254 | 3 | 0 | 3 |
| ATXN7L3B | TRIM26 | 0.755893 | 3 | 0 | 3 |
| ATXN7L3B | ZBED4 | 0.755237 | 3 | 0 | 3 |
| ATXN7L3B | LDLRAP1 | 0.75294 | 3 | 0 | 3 |
| ATXN7L3B | GPR107 | 0.748053 | 3 | 0 | 3 |
| ATXN7L3B | TTC31 | 0.747924 | 3 | 0 | 3 |
| ATXN7L3B | PROSER1 | 0.745964 | 3 | 0 | 3 |
| ATXN7L3B | ABHD16A | 0.745595 | 3 | 0 | 3 |
| ATXN7L3B | ZFX | 0.745015 | 3 | 0 | 3 |
| ATXN7L3B | TBRG4 | 0.743085 | 3 | 0 | 3 |
| ATXN7L3B | SP1 | 0.740012 | 4 | 0 | 3 |
For details and further investigation, click here
