| Full name: tubulin epsilon 1 | Alias Symbol: dJ142L7.2|FLJ22589|TUBE | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 51175 | HGNC ID: HGNC:20775 | Ensembl Gene: ENSG00000074935 | OMIM ID: 607345 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TUBE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBE1 | 51175 | 226181_at | -0.4497 | 0.2848 | |
| GSE26886 | TUBE1 | 51175 | 226181_at | -0.0185 | 0.9632 | |
| GSE45670 | TUBE1 | 51175 | 226181_at | -0.2433 | 0.2034 | |
| GSE63941 | TUBE1 | 51175 | 226181_at | 0.0996 | 0.9196 | |
| GSE77861 | TUBE1 | 51175 | 226181_at | 0.1561 | 0.7931 | |
| GSE97050 | TUBE1 | 51175 | A_33_P3240538 | -0.1433 | 0.5396 | |
| SRP007169 | TUBE1 | 51175 | RNAseq | 0.6511 | 0.1459 | |
| SRP008496 | TUBE1 | 51175 | RNAseq | 0.5560 | 0.1001 | |
| SRP064894 | TUBE1 | 51175 | RNAseq | -0.3622 | 0.1172 | |
| SRP133303 | TUBE1 | 51175 | RNAseq | 0.0110 | 0.9545 | |
| SRP159526 | TUBE1 | 51175 | RNAseq | -0.3817 | 0.0831 | |
| SRP193095 | TUBE1 | 51175 | RNAseq | -0.2193 | 0.0464 | |
| SRP219564 | TUBE1 | 51175 | RNAseq | -0.1364 | 0.6016 | |
| TCGA | TUBE1 | 51175 | RNAseq | -0.3556 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TUBE1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TUBE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBE1 | 51175 | 2 | 4 | 24 | |
| GSE20123 | TUBE1 | 51175 | 2 | 3 | 25 | |
| GSE43470 | TUBE1 | 51175 | 3 | 1 | 39 | |
| GSE46452 | TUBE1 | 51175 | 2 | 11 | 46 | |
| GSE47630 | TUBE1 | 51175 | 9 | 4 | 27 | |
| GSE54993 | TUBE1 | 51175 | 3 | 2 | 65 | |
| GSE54994 | TUBE1 | 51175 | 8 | 8 | 37 | |
| GSE60625 | TUBE1 | 51175 | 0 | 2 | 9 | |
| GSE74703 | TUBE1 | 51175 | 2 | 1 | 33 | |
| GSE74704 | TUBE1 | 51175 | 0 | 1 | 19 | |
| TCGA | TUBE1 | 51175 | 6 | 23 | 67 |
Total number of gains: 37; Total number of losses: 60; Total Number of normals: 391.
Somatic mutations of TUBE1:
Generating mutation plots.
Highly correlated genes for TUBE1:
Showing top 20/166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBE1 | GOLPH3 | 0.801694 | 3 | 0 | 3 |
| TUBE1 | ENTPD4 | 0.794531 | 3 | 0 | 3 |
| TUBE1 | MTMR12 | 0.786264 | 3 | 0 | 3 |
| TUBE1 | ARL5B | 0.753244 | 3 | 0 | 3 |
| TUBE1 | FBXO9 | 0.733279 | 3 | 0 | 3 |
| TUBE1 | RB1CC1 | 0.731524 | 4 | 0 | 4 |
| TUBE1 | SORL1 | 0.727108 | 3 | 0 | 3 |
| TUBE1 | AUH | 0.725953 | 3 | 0 | 3 |
| TUBE1 | NBPF1 | 0.724627 | 3 | 0 | 3 |
| TUBE1 | INTS8 | 0.716514 | 3 | 0 | 3 |
| TUBE1 | AP3M2 | 0.71576 | 3 | 0 | 3 |
| TUBE1 | CHMP7 | 0.710058 | 3 | 0 | 3 |
| TUBE1 | FAM98B | 0.708098 | 3 | 0 | 3 |
| TUBE1 | ARMC1 | 0.705556 | 3 | 0 | 3 |
| TUBE1 | TRAF5 | 0.705504 | 3 | 0 | 3 |
| TUBE1 | P4HTM | 0.705054 | 3 | 0 | 3 |
| TUBE1 | KIAA1107 | 0.703674 | 3 | 0 | 3 |
| TUBE1 | HOOK3 | 0.701721 | 3 | 0 | 3 |
| TUBE1 | SLC38A1 | 0.699214 | 3 | 0 | 3 |
| TUBE1 | ID4 | 0.697424 | 3 | 0 | 3 |
For details and further investigation, click here
