| Full name: UPF3B regulator of nonsense mediated mRNA decay | Alias Symbol: RENT3B|UPF3X|HUPF3B | ||
| Type: protein-coding gene | Cytoband: Xq24 | ||
| Entrez ID: 65109 | HGNC ID: HGNC:20439 | Ensembl Gene: ENSG00000125351 | OMIM ID: 300298 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UPF3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UPF3B | 65109 | 218757_s_at | -0.0571 | 0.8757 | |
| GSE20347 | UPF3B | 65109 | 218757_s_at | 0.6531 | 0.0000 | |
| GSE23400 | UPF3B | 65109 | 218757_s_at | 0.7612 | 0.0000 | |
| GSE26886 | UPF3B | 65109 | 218757_s_at | 0.3471 | 0.2060 | |
| GSE29001 | UPF3B | 65109 | 218757_s_at | 0.7687 | 0.0137 | |
| GSE38129 | UPF3B | 65109 | 218757_s_at | 0.6891 | 0.0000 | |
| GSE45670 | UPF3B | 65109 | 218757_s_at | 0.2131 | 0.2688 | |
| GSE53622 | UPF3B | 65109 | 145129 | 0.4253 | 0.0000 | |
| GSE53624 | UPF3B | 65109 | 145129 | 0.4008 | 0.0000 | |
| GSE63941 | UPF3B | 65109 | 218757_s_at | 1.3921 | 0.0052 | |
| GSE77861 | UPF3B | 65109 | 218757_s_at | 0.1659 | 0.6483 | |
| GSE97050 | UPF3B | 65109 | A_24_P310630 | -0.1557 | 0.4292 | |
| SRP007169 | UPF3B | 65109 | RNAseq | 1.6415 | 0.0570 | |
| SRP064894 | UPF3B | 65109 | RNAseq | 0.4104 | 0.0029 | |
| SRP133303 | UPF3B | 65109 | RNAseq | 0.4630 | 0.0461 | |
| SRP159526 | UPF3B | 65109 | RNAseq | 0.1382 | 0.6765 | |
| SRP193095 | UPF3B | 65109 | RNAseq | 0.1173 | 0.4672 | |
| SRP219564 | UPF3B | 65109 | RNAseq | -0.0273 | 0.9290 | |
| TCGA | UPF3B | 65109 | RNAseq | 0.1532 | 0.0453 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by UPF3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UPF3B:
No record found for this gene.
Somatic mutations of UPF3B:
Generating mutation plots.
Highly correlated genes for UPF3B:
Showing top 20/815 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UPF3B | CCDC146 | 0.762364 | 3 | 0 | 3 |
| UPF3B | ATG14 | 0.753468 | 4 | 0 | 4 |
| UPF3B | RHBDD1 | 0.750472 | 3 | 0 | 3 |
| UPF3B | SRP68 | 0.745447 | 3 | 0 | 3 |
| UPF3B | BABAM1 | 0.742652 | 3 | 0 | 3 |
| UPF3B | FAM122B | 0.740733 | 4 | 0 | 4 |
| UPF3B | MTMR12 | 0.733847 | 3 | 0 | 3 |
| UPF3B | COG1 | 0.732273 | 3 | 0 | 3 |
| UPF3B | ZNF398 | 0.73204 | 3 | 0 | 3 |
| UPF3B | DMAP1 | 0.72934 | 4 | 0 | 4 |
| UPF3B | STX16 | 0.723976 | 3 | 0 | 3 |
| UPF3B | UXT | 0.715582 | 3 | 0 | 3 |
| UPF3B | PRKAG1 | 0.714216 | 3 | 0 | 3 |
| UPF3B | PUS7L | 0.713285 | 4 | 0 | 3 |
| UPF3B | TSNARE1 | 0.710633 | 3 | 0 | 3 |
| UPF3B | KCTD1 | 0.704983 | 3 | 0 | 3 |
| UPF3B | ZNF664 | 0.702379 | 5 | 0 | 4 |
| UPF3B | RPS24 | 0.70069 | 4 | 0 | 4 |
| UPF3B | THAP5 | 0.699584 | 3 | 0 | 3 |
| UPF3B | C11orf1 | 0.697557 | 3 | 0 | 3 |
For details and further investigation, click here
