| Full name: dedicator of cytokinesis 7 | Alias Symbol: KIAA1771|ZIR2 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 85440 | HGNC ID: HGNC:19190 | Ensembl Gene: ENSG00000116641 | OMIM ID: 615730 |
| Drug and gene relationship at DGIdb | |||
Expression of DOCK7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DOCK7 | 85440 | 225384_at | 0.1676 | 0.8077 | |
| GSE26886 | DOCK7 | 85440 | 225384_at | 0.8807 | 0.0047 | |
| GSE45670 | DOCK7 | 85440 | 225384_at | -0.1297 | 0.5988 | |
| GSE53622 | DOCK7 | 85440 | 52789 | 0.4300 | 0.0000 | |
| GSE53624 | DOCK7 | 85440 | 75396 | 0.4067 | 0.0001 | |
| GSE63941 | DOCK7 | 85440 | 225384_at | -1.7881 | 0.0013 | |
| GSE77861 | DOCK7 | 85440 | 225384_at | 0.3708 | 0.2792 | |
| GSE97050 | DOCK7 | 85440 | A_24_P203622 | 0.1076 | 0.5944 | |
| SRP007169 | DOCK7 | 85440 | RNAseq | 0.6042 | 0.1202 | |
| SRP008496 | DOCK7 | 85440 | RNAseq | 0.7302 | 0.0010 | |
| SRP064894 | DOCK7 | 85440 | RNAseq | 0.3728 | 0.0883 | |
| SRP133303 | DOCK7 | 85440 | RNAseq | 0.5302 | 0.0002 | |
| SRP159526 | DOCK7 | 85440 | RNAseq | -0.0885 | 0.6815 | |
| SRP193095 | DOCK7 | 85440 | RNAseq | 0.2042 | 0.1424 | |
| SRP219564 | DOCK7 | 85440 | RNAseq | 0.3303 | 0.4107 | |
| TCGA | DOCK7 | 85440 | RNAseq | -0.0869 | 0.1141 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DOCK7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DOCK7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DOCK7 | 85440 | 3 | 6 | 21 | |
| GSE20123 | DOCK7 | 85440 | 3 | 5 | 22 | |
| GSE43470 | DOCK7 | 85440 | 5 | 2 | 36 | |
| GSE46452 | DOCK7 | 85440 | 1 | 1 | 57 | |
| GSE47630 | DOCK7 | 85440 | 8 | 5 | 27 | |
| GSE54993 | DOCK7 | 85440 | 0 | 0 | 70 | |
| GSE54994 | DOCK7 | 85440 | 6 | 4 | 43 | |
| GSE60625 | DOCK7 | 85440 | 0 | 0 | 11 | |
| GSE74703 | DOCK7 | 85440 | 4 | 2 | 30 | |
| GSE74704 | DOCK7 | 85440 | 2 | 2 | 16 | |
| TCGA | DOCK7 | 85440 | 10 | 20 | 66 |
Total number of gains: 42; Total number of losses: 47; Total Number of normals: 399.
Somatic mutations of DOCK7:
Generating mutation plots.
Highly correlated genes for DOCK7:
Showing top 20/1220 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DOCK7 | NPAT | 0.807836 | 3 | 0 | 3 |
| DOCK7 | MCM3AP | 0.794545 | 3 | 0 | 3 |
| DOCK7 | PMPCB | 0.788665 | 4 | 0 | 4 |
| DOCK7 | NUB1 | 0.774314 | 3 | 0 | 3 |
| DOCK7 | ZDHHC7 | 0.774195 | 4 | 0 | 4 |
| DOCK7 | STK32B | 0.774113 | 3 | 0 | 3 |
| DOCK7 | MAPK1 | 0.764389 | 3 | 0 | 3 |
| DOCK7 | ZNF764 | 0.763196 | 3 | 0 | 3 |
| DOCK7 | NEK7 | 0.762535 | 5 | 0 | 5 |
| DOCK7 | NARF | 0.756191 | 3 | 0 | 3 |
| DOCK7 | ZNF578 | 0.755722 | 3 | 0 | 3 |
| DOCK7 | RWDD2A | 0.753499 | 3 | 0 | 3 |
| DOCK7 | ADH5 | 0.750722 | 5 | 0 | 5 |
| DOCK7 | ZNF23 | 0.744158 | 3 | 0 | 3 |
| DOCK7 | DHX40 | 0.74363 | 4 | 0 | 3 |
| DOCK7 | PTGER4 | 0.743598 | 4 | 0 | 4 |
| DOCK7 | SDHB | 0.738214 | 4 | 0 | 3 |
| DOCK7 | ADAT1 | 0.737801 | 4 | 0 | 3 |
| DOCK7 | TMC7 | 0.733191 | 3 | 0 | 3 |
| DOCK7 | C16orf46 | 0.733098 | 3 | 0 | 3 |
For details and further investigation, click here
