| Full name: myotubularin related protein 4 | Alias Symbol: KIAA0647|ZFYVE11 | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 9110 | HGNC ID: HGNC:7452 | Ensembl Gene: ENSG00000108389 | OMIM ID: 603559 |
| Drug and gene relationship at DGIdb | |||
Expression of MTMR4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTMR4 | 9110 | 212277_at | 0.3721 | 0.2607 | |
| GSE20347 | MTMR4 | 9110 | 214268_s_at | 0.3937 | 0.0032 | |
| GSE23400 | MTMR4 | 9110 | 214268_s_at | 0.1955 | 0.0063 | |
| GSE26886 | MTMR4 | 9110 | 214268_s_at | 0.1709 | 0.2395 | |
| GSE29001 | MTMR4 | 9110 | 214268_s_at | 0.2764 | 0.2592 | |
| GSE38129 | MTMR4 | 9110 | 214268_s_at | 0.3757 | 0.0002 | |
| GSE45670 | MTMR4 | 9110 | 212277_at | 0.0813 | 0.6275 | |
| GSE53622 | MTMR4 | 9110 | 151457 | 0.0416 | 0.6380 | |
| GSE53624 | MTMR4 | 9110 | 151457 | 0.1226 | 0.0456 | |
| GSE63941 | MTMR4 | 9110 | 212277_at | -0.2564 | 0.5134 | |
| GSE77861 | MTMR4 | 9110 | 214268_s_at | 0.1386 | 0.5533 | |
| GSE97050 | MTMR4 | 9110 | A_24_P382119 | -0.0863 | 0.7426 | |
| SRP007169 | MTMR4 | 9110 | RNAseq | 1.0403 | 0.0161 | |
| SRP008496 | MTMR4 | 9110 | RNAseq | 1.1268 | 0.0001 | |
| SRP064894 | MTMR4 | 9110 | RNAseq | 0.0007 | 0.9969 | |
| SRP133303 | MTMR4 | 9110 | RNAseq | 0.3639 | 0.0485 | |
| SRP159526 | MTMR4 | 9110 | RNAseq | 0.2356 | 0.3578 | |
| SRP193095 | MTMR4 | 9110 | RNAseq | -0.1363 | 0.1018 | |
| SRP219564 | MTMR4 | 9110 | RNAseq | 0.4052 | 0.4177 | |
| TCGA | MTMR4 | 9110 | RNAseq | -0.0571 | 0.2466 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MTMR4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTMR4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTMR4 | 9110 | 5 | 1 | 24 | |
| GSE20123 | MTMR4 | 9110 | 5 | 1 | 24 | |
| GSE43470 | MTMR4 | 9110 | 3 | 0 | 40 | |
| GSE46452 | MTMR4 | 9110 | 32 | 0 | 27 | |
| GSE47630 | MTMR4 | 9110 | 7 | 1 | 32 | |
| GSE54993 | MTMR4 | 9110 | 2 | 5 | 63 | |
| GSE54994 | MTMR4 | 9110 | 8 | 6 | 39 | |
| GSE60625 | MTMR4 | 9110 | 4 | 0 | 7 | |
| GSE74703 | MTMR4 | 9110 | 3 | 0 | 33 | |
| GSE74704 | MTMR4 | 9110 | 4 | 1 | 15 | |
| TCGA | MTMR4 | 9110 | 27 | 8 | 61 |
Total number of gains: 100; Total number of losses: 23; Total Number of normals: 365.
Somatic mutations of MTMR4:
Generating mutation plots.
Highly correlated genes for MTMR4:
Showing top 20/533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTMR4 | GORAB | 0.774662 | 3 | 0 | 3 |
| MTMR4 | TGFBRAP1 | 0.764858 | 3 | 0 | 3 |
| MTMR4 | RHBDD2 | 0.751871 | 3 | 0 | 3 |
| MTMR4 | SENP5 | 0.748418 | 4 | 0 | 4 |
| MTMR4 | ZBED1 | 0.735422 | 3 | 0 | 3 |
| MTMR4 | CRTC2 | 0.731467 | 3 | 0 | 3 |
| MTMR4 | TMEM170A | 0.725093 | 3 | 0 | 3 |
| MTMR4 | GRB2 | 0.716423 | 4 | 0 | 4 |
| MTMR4 | TULP4 | 0.715984 | 4 | 0 | 3 |
| MTMR4 | NBPF1 | 0.715354 | 3 | 0 | 3 |
| MTMR4 | ZNF260 | 0.713306 | 4 | 0 | 3 |
| MTMR4 | FAM168A | 0.712945 | 3 | 0 | 3 |
| MTMR4 | SFXN2 | 0.710346 | 3 | 0 | 3 |
| MTMR4 | GDPD1 | 0.707419 | 3 | 0 | 3 |
| MTMR4 | USP33 | 0.706501 | 3 | 0 | 3 |
| MTMR4 | OTUD3 | 0.697605 | 3 | 0 | 3 |
| MTMR4 | POMGNT1 | 0.695453 | 3 | 0 | 3 |
| MTMR4 | CNIH3 | 0.695123 | 3 | 0 | 3 |
| MTMR4 | FBXO33 | 0.694412 | 3 | 0 | 3 |
| MTMR4 | C5orf51 | 0.692211 | 3 | 0 | 3 |
For details and further investigation, click here
