| Full name: ubiquitin specific peptidase 33 | Alias Symbol: KIAA1097|VDU1 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 23032 | HGNC ID: HGNC:20059 | Ensembl Gene: ENSG00000077254 | OMIM ID: 615146 |
| Drug and gene relationship at DGIdb | |||
Expression of USP33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP33 | 23032 | 212513_s_at | -0.0306 | 0.9108 | |
| GSE20347 | USP33 | 23032 | 212513_s_at | -0.0183 | 0.9128 | |
| GSE23400 | USP33 | 23032 | 212513_s_at | 0.0953 | 0.2851 | |
| GSE26886 | USP33 | 23032 | 212513_s_at | -0.1472 | 0.5986 | |
| GSE29001 | USP33 | 23032 | 214843_s_at | 0.1029 | 0.7934 | |
| GSE38129 | USP33 | 23032 | 212513_s_at | -0.0481 | 0.6888 | |
| GSE45670 | USP33 | 23032 | 212513_s_at | -0.0851 | 0.5761 | |
| GSE53622 | USP33 | 23032 | 149561 | -0.5541 | 0.0000 | |
| GSE53624 | USP33 | 23032 | 76059 | -0.1457 | 0.0149 | |
| GSE63941 | USP33 | 23032 | 212513_s_at | -0.8639 | 0.0180 | |
| GSE77861 | USP33 | 23032 | 212513_s_at | -0.1865 | 0.5658 | |
| GSE97050 | USP33 | 23032 | A_24_P405190 | -0.4176 | 0.1403 | |
| SRP007169 | USP33 | 23032 | RNAseq | 0.0251 | 0.9315 | |
| SRP008496 | USP33 | 23032 | RNAseq | -0.0469 | 0.7604 | |
| SRP064894 | USP33 | 23032 | RNAseq | -0.0669 | 0.7107 | |
| SRP133303 | USP33 | 23032 | RNAseq | -0.0029 | 0.9769 | |
| SRP159526 | USP33 | 23032 | RNAseq | -0.3153 | 0.2756 | |
| SRP193095 | USP33 | 23032 | RNAseq | -0.2047 | 0.0343 | |
| SRP219564 | USP33 | 23032 | RNAseq | 0.2138 | 0.5450 | |
| TCGA | USP33 | 23032 | RNAseq | -0.0662 | 0.1578 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP33 | 23032 | 0 | 7 | 23 | |
| GSE20123 | USP33 | 23032 | 0 | 7 | 23 | |
| GSE43470 | USP33 | 23032 | 3 | 3 | 37 | |
| GSE46452 | USP33 | 23032 | 0 | 1 | 58 | |
| GSE47630 | USP33 | 23032 | 8 | 6 | 26 | |
| GSE54993 | USP33 | 23032 | 0 | 0 | 70 | |
| GSE54994 | USP33 | 23032 | 6 | 3 | 44 | |
| GSE60625 | USP33 | 23032 | 0 | 0 | 11 | |
| GSE74703 | USP33 | 23032 | 2 | 3 | 31 | |
| GSE74704 | USP33 | 23032 | 0 | 4 | 16 | |
| TCGA | USP33 | 23032 | 7 | 25 | 64 |
Total number of gains: 26; Total number of losses: 59; Total Number of normals: 403.
Somatic mutations of USP33:
Generating mutation plots.
Highly correlated genes for USP33:
Showing top 20/383 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP33 | ST6GALNAC6 | 0.784671 | 3 | 0 | 3 |
| USP33 | AKAP9 | 0.784102 | 3 | 0 | 3 |
| USP33 | ZNF655 | 0.777427 | 3 | 0 | 3 |
| USP33 | DENND4C | 0.776025 | 3 | 0 | 3 |
| USP33 | SLC25A40 | 0.746164 | 3 | 0 | 3 |
| USP33 | KIAA1143 | 0.745396 | 3 | 0 | 3 |
| USP33 | CCNT1 | 0.74056 | 3 | 0 | 3 |
| USP33 | DMXL1 | 0.739135 | 4 | 0 | 4 |
| USP33 | TADA2B | 0.737885 | 3 | 0 | 3 |
| USP33 | FNIP1 | 0.737363 | 3 | 0 | 3 |
| USP33 | ADH1C | 0.730863 | 3 | 0 | 3 |
| USP33 | MRPS36 | 0.729325 | 3 | 0 | 3 |
| USP33 | ABCA8 | 0.722988 | 3 | 0 | 3 |
| USP33 | CST3 | 0.71953 | 3 | 0 | 3 |
| USP33 | ZNF136 | 0.718063 | 3 | 0 | 3 |
| USP33 | NFIX | 0.716074 | 3 | 0 | 3 |
| USP33 | UTRN | 0.715686 | 3 | 0 | 3 |
| USP33 | RBM18 | 0.712346 | 4 | 0 | 3 |
| USP33 | RCAN2 | 0.712117 | 3 | 0 | 3 |
| USP33 | ADH1B | 0.708223 | 3 | 0 | 3 |
For details and further investigation, click here
