| Full name: protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | Alias Symbol: FLJ20277|MGAT1.2|LGMD2O | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 55624 | HGNC ID: HGNC:19139 | Ensembl Gene: ENSG00000085998 | OMIM ID: 606822 |
| Drug and gene relationship at DGIdb | |||
Expression of POMGNT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POMGNT1 | 55624 | 217944_at | 0.9870 | 0.1173 | |
| GSE20347 | POMGNT1 | 55624 | 217944_at | 0.8487 | 0.0000 | |
| GSE23400 | POMGNT1 | 55624 | 217944_at | 0.4013 | 0.0000 | |
| GSE26886 | POMGNT1 | 55624 | 217944_at | 0.9934 | 0.0009 | |
| GSE29001 | POMGNT1 | 55624 | 217944_at | 0.4734 | 0.0132 | |
| GSE38129 | POMGNT1 | 55624 | 217944_at | 0.8546 | 0.0000 | |
| GSE45670 | POMGNT1 | 55624 | 217944_at | 0.5905 | 0.0129 | |
| GSE53622 | POMGNT1 | 55624 | 26435 | 0.5363 | 0.0000 | |
| GSE53624 | POMGNT1 | 55624 | 26435 | 0.8111 | 0.0000 | |
| GSE63941 | POMGNT1 | 55624 | 217944_at | -0.6216 | 0.3284 | |
| GSE77861 | POMGNT1 | 55624 | 217944_at | 0.5879 | 0.0872 | |
| GSE97050 | POMGNT1 | 55624 | A_33_P3284197 | 0.1475 | 0.5139 | |
| SRP007169 | POMGNT1 | 55624 | RNAseq | 0.7009 | 0.0979 | |
| SRP008496 | POMGNT1 | 55624 | RNAseq | 0.6147 | 0.0274 | |
| SRP064894 | POMGNT1 | 55624 | RNAseq | 0.9308 | 0.0000 | |
| SRP133303 | POMGNT1 | 55624 | RNAseq | 0.8171 | 0.0000 | |
| SRP159526 | POMGNT1 | 55624 | RNAseq | 0.9030 | 0.0000 | |
| SRP193095 | POMGNT1 | 55624 | RNAseq | 0.7532 | 0.0000 | |
| SRP219564 | POMGNT1 | 55624 | RNAseq | 0.6612 | 0.0968 | |
| TCGA | POMGNT1 | 55624 | RNAseq | -0.0418 | 0.4089 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POMGNT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POMGNT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POMGNT1 | 55624 | 4 | 3 | 23 | |
| GSE20123 | POMGNT1 | 55624 | 4 | 2 | 24 | |
| GSE43470 | POMGNT1 | 55624 | 5 | 2 | 36 | |
| GSE46452 | POMGNT1 | 55624 | 2 | 1 | 56 | |
| GSE47630 | POMGNT1 | 55624 | 8 | 4 | 28 | |
| GSE54993 | POMGNT1 | 55624 | 0 | 1 | 69 | |
| GSE54994 | POMGNT1 | 55624 | 11 | 2 | 40 | |
| GSE60625 | POMGNT1 | 55624 | 0 | 0 | 11 | |
| GSE74703 | POMGNT1 | 55624 | 4 | 1 | 31 | |
| GSE74704 | POMGNT1 | 55624 | 2 | 0 | 18 | |
| TCGA | POMGNT1 | 55624 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 33; Total Number of normals: 405.
Somatic mutations of POMGNT1:
Generating mutation plots.
Highly correlated genes for POMGNT1:
Showing top 20/1923 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POMGNT1 | DOCK6 | 0.81963 | 3 | 0 | 3 |
| POMGNT1 | KLHL36 | 0.797858 | 3 | 0 | 3 |
| POMGNT1 | ZNF644 | 0.777767 | 3 | 0 | 3 |
| POMGNT1 | USP34 | 0.765779 | 3 | 0 | 3 |
| POMGNT1 | DYNLRB1 | 0.762077 | 3 | 0 | 3 |
| POMGNT1 | PEX10 | 0.759977 | 3 | 0 | 3 |
| POMGNT1 | AURKAIP1 | 0.755581 | 4 | 0 | 4 |
| POMGNT1 | C6orf141 | 0.73934 | 3 | 0 | 3 |
| POMGNT1 | FADS1 | 0.737715 | 3 | 0 | 3 |
| POMGNT1 | KRTCAP2 | 0.735295 | 5 | 0 | 4 |
| POMGNT1 | MAD2L2 | 0.735065 | 6 | 0 | 5 |
| POMGNT1 | CERS2 | 0.734546 | 9 | 0 | 9 |
| POMGNT1 | NARF | 0.727864 | 4 | 0 | 4 |
| POMGNT1 | TET1 | 0.724726 | 3 | 0 | 3 |
| POMGNT1 | BRAT1 | 0.724232 | 6 | 0 | 6 |
| POMGNT1 | CRTC2 | 0.72417 | 5 | 0 | 5 |
| POMGNT1 | SLC35B2 | 0.722808 | 3 | 0 | 3 |
| POMGNT1 | RPS19BP1 | 0.721601 | 4 | 0 | 3 |
| POMGNT1 | ERI3 | 0.719517 | 11 | 0 | 9 |
| POMGNT1 | PPT1 | 0.716007 | 11 | 0 | 11 |
For details and further investigation, click here
