| Full name: glycerophosphodiester phosphodiesterase domain containing 1 | Alias Symbol: FLJ37451|GDE4 | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 284161 | HGNC ID: HGNC:20883 | Ensembl Gene: ENSG00000153982 | OMIM ID: 616317 |
| Drug and gene relationship at DGIdb | |||
Expression of GDPD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDPD1 | 284161 | 238681_at | -0.4804 | 0.4652 | |
| GSE26886 | GDPD1 | 284161 | 238681_at | 0.6529 | 0.0751 | |
| GSE45670 | GDPD1 | 284161 | 238681_at | 0.1962 | 0.5895 | |
| GSE53622 | GDPD1 | 284161 | 116898 | -0.3569 | 0.0084 | |
| GSE53624 | GDPD1 | 284161 | 116898 | -0.1759 | 0.0935 | |
| GSE63941 | GDPD1 | 284161 | 238681_at | 0.0538 | 0.9618 | |
| GSE77861 | GDPD1 | 284161 | 1555606_a_at | 0.0369 | 0.6495 | |
| GSE97050 | GDPD1 | 284161 | A_23_P84666 | -0.3764 | 0.1745 | |
| SRP007169 | GDPD1 | 284161 | RNAseq | -0.2727 | 0.6334 | |
| SRP008496 | GDPD1 | 284161 | RNAseq | 0.3127 | 0.4393 | |
| SRP064894 | GDPD1 | 284161 | RNAseq | -0.0798 | 0.7289 | |
| SRP133303 | GDPD1 | 284161 | RNAseq | 0.0710 | 0.6718 | |
| SRP159526 | GDPD1 | 284161 | RNAseq | 0.4694 | 0.2818 | |
| SRP193095 | GDPD1 | 284161 | RNAseq | -0.7239 | 0.0004 | |
| SRP219564 | GDPD1 | 284161 | RNAseq | 0.0572 | 0.8557 | |
| TCGA | GDPD1 | 284161 | RNAseq | -0.7093 | 0.0039 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GDPD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDPD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDPD1 | 284161 | 6 | 1 | 23 | |
| GSE20123 | GDPD1 | 284161 | 6 | 1 | 23 | |
| GSE43470 | GDPD1 | 284161 | 3 | 0 | 40 | |
| GSE46452 | GDPD1 | 284161 | 32 | 0 | 27 | |
| GSE47630 | GDPD1 | 284161 | 7 | 1 | 32 | |
| GSE54993 | GDPD1 | 284161 | 2 | 5 | 63 | |
| GSE54994 | GDPD1 | 284161 | 9 | 5 | 39 | |
| GSE60625 | GDPD1 | 284161 | 4 | 0 | 7 | |
| GSE74703 | GDPD1 | 284161 | 3 | 0 | 33 | |
| GSE74704 | GDPD1 | 284161 | 5 | 1 | 14 | |
| TCGA | GDPD1 | 284161 | 26 | 7 | 63 |
Total number of gains: 103; Total number of losses: 21; Total Number of normals: 364.
Somatic mutations of GDPD1:
Generating mutation plots.
Highly correlated genes for GDPD1:
Showing top 20/199 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDPD1 | MSL3 | 0.819238 | 3 | 0 | 3 |
| GDPD1 | ZNF93 | 0.801502 | 3 | 0 | 3 |
| GDPD1 | ZKSCAN1 | 0.793581 | 3 | 0 | 3 |
| GDPD1 | SLC44A4 | 0.76278 | 3 | 0 | 3 |
| GDPD1 | IPP | 0.761191 | 4 | 0 | 3 |
| GDPD1 | CLOCK | 0.76017 | 3 | 0 | 3 |
| GDPD1 | EIF2AK4 | 0.757638 | 4 | 0 | 4 |
| GDPD1 | ZNF626 | 0.756189 | 3 | 0 | 3 |
| GDPD1 | FZD7 | 0.753807 | 3 | 0 | 3 |
| GDPD1 | DAP | 0.742996 | 3 | 0 | 3 |
| GDPD1 | TMEM218 | 0.740552 | 5 | 0 | 5 |
| GDPD1 | ZNF202 | 0.726354 | 3 | 0 | 3 |
| GDPD1 | SACS | 0.722417 | 3 | 0 | 3 |
| GDPD1 | PPM1K | 0.721678 | 4 | 0 | 3 |
| GDPD1 | SULT1A1 | 0.718544 | 3 | 0 | 3 |
| GDPD1 | ATP6V0E2 | 0.714211 | 3 | 0 | 3 |
| GDPD1 | TACC2 | 0.712628 | 3 | 0 | 3 |
| GDPD1 | SLIT2 | 0.709957 | 3 | 0 | 3 |
| GDPD1 | MTMR4 | 0.707419 | 3 | 0 | 3 |
| GDPD1 | TMEM62 | 0.706671 | 3 | 0 | 3 |
For details and further investigation, click here
