| Full name: SUMO specific peptidase 5 | Alias Symbol: MGC27076 | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 205564 | HGNC ID: HGNC:28407 | Ensembl Gene: ENSG00000119231 | OMIM ID: 612845 |
| Drug and gene relationship at DGIdb | |||
Expression of SENP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SENP5 | 205564 | 213184_at | 0.6146 | 0.0852 | |
| GSE20347 | SENP5 | 205564 | 213184_at | 0.3057 | 0.0137 | |
| GSE23400 | SENP5 | 205564 | 213184_at | 0.1245 | 0.0117 | |
| GSE26886 | SENP5 | 205564 | 213184_at | 0.4873 | 0.0172 | |
| GSE29001 | SENP5 | 205564 | 213184_at | 0.5772 | 0.0154 | |
| GSE38129 | SENP5 | 205564 | 213184_at | 0.2878 | 0.0051 | |
| GSE45670 | SENP5 | 205564 | 213184_at | 0.4321 | 0.0014 | |
| GSE53622 | SENP5 | 205564 | 53888 | 0.6318 | 0.0000 | |
| GSE53624 | SENP5 | 205564 | 53888 | 0.8272 | 0.0000 | |
| GSE63941 | SENP5 | 205564 | 213184_at | 0.0636 | 0.8926 | |
| GSE77861 | SENP5 | 205564 | 213184_at | 0.2307 | 0.4156 | |
| GSE97050 | SENP5 | 205564 | A_32_P32653 | 0.1415 | 0.6811 | |
| SRP007169 | SENP5 | 205564 | RNAseq | 1.3391 | 0.0006 | |
| SRP008496 | SENP5 | 205564 | RNAseq | 1.7104 | 0.0000 | |
| SRP064894 | SENP5 | 205564 | RNAseq | 0.4525 | 0.0104 | |
| SRP133303 | SENP5 | 205564 | RNAseq | 0.9000 | 0.0000 | |
| SRP159526 | SENP5 | 205564 | RNAseq | 1.0359 | 0.0005 | |
| SRP193095 | SENP5 | 205564 | RNAseq | 0.7530 | 0.0000 | |
| SRP219564 | SENP5 | 205564 | RNAseq | 0.4541 | 0.1417 | |
| TCGA | SENP5 | 205564 | RNAseq | 0.1394 | 0.0091 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SENP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SENP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SENP5 | 205564 | 22 | 0 | 8 | |
| GSE20123 | SENP5 | 205564 | 22 | 0 | 8 | |
| GSE43470 | SENP5 | 205564 | 21 | 0 | 22 | |
| GSE46452 | SENP5 | 205564 | 20 | 1 | 38 | |
| GSE47630 | SENP5 | 205564 | 27 | 2 | 11 | |
| GSE54993 | SENP5 | 205564 | 1 | 22 | 47 | |
| GSE54994 | SENP5 | 205564 | 41 | 0 | 12 | |
| GSE60625 | SENP5 | 205564 | 0 | 6 | 5 | |
| GSE74703 | SENP5 | 205564 | 19 | 0 | 17 | |
| GSE74704 | SENP5 | 205564 | 14 | 0 | 6 | |
| TCGA | SENP5 | 205564 | 76 | 1 | 19 |
Total number of gains: 263; Total number of losses: 32; Total Number of normals: 193.
Somatic mutations of SENP5:
Generating mutation plots.
Highly correlated genes for SENP5:
Showing top 20/978 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SENP5 | TBC1D25 | 0.833517 | 3 | 0 | 3 |
| SENP5 | METAP1D | 0.820886 | 3 | 0 | 3 |
| SENP5 | UBIAD1 | 0.809705 | 3 | 0 | 3 |
| SENP5 | TMEM63B | 0.783549 | 3 | 0 | 3 |
| SENP5 | STRN4 | 0.77086 | 3 | 0 | 3 |
| SENP5 | RFNG | 0.76725 | 3 | 0 | 3 |
| SENP5 | PRR12 | 0.76605 | 3 | 0 | 3 |
| SENP5 | GPR107 | 0.755759 | 3 | 0 | 3 |
| SENP5 | MTMR4 | 0.748418 | 4 | 0 | 4 |
| SENP5 | ZNF518B | 0.746584 | 4 | 0 | 4 |
| SENP5 | CIC | 0.746251 | 4 | 0 | 4 |
| SENP5 | ANAPC5 | 0.740874 | 4 | 0 | 4 |
| SENP5 | PPP1R16A | 0.740769 | 3 | 0 | 3 |
| SENP5 | ZNF628 | 0.738192 | 3 | 0 | 3 |
| SENP5 | INTS3 | 0.734213 | 3 | 0 | 3 |
| SENP5 | ERP27 | 0.730509 | 3 | 0 | 3 |
| SENP5 | RILPL1 | 0.726243 | 3 | 0 | 3 |
| SENP5 | FH | 0.726005 | 3 | 0 | 3 |
| SENP5 | PACS1 | 0.725402 | 4 | 0 | 3 |
| SENP5 | RILPL2 | 0.720777 | 3 | 0 | 3 |
For details and further investigation, click here
