| Full name: OTU deubiquitinase 3 | Alias Symbol: KIAA0459|DUBA4 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 23252 | HGNC ID: HGNC:29038 | Ensembl Gene: ENSG00000169914 | OMIM ID: 611758 |
| Drug and gene relationship at DGIdb | |||
Expression of OTUD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTUD3 | 23252 | 213216_at | 0.4231 | 0.2887 | |
| GSE20347 | OTUD3 | 23252 | 213216_at | 0.2492 | 0.0306 | |
| GSE23400 | OTUD3 | 23252 | 213216_at | 0.1533 | 0.0147 | |
| GSE26886 | OTUD3 | 23252 | 213216_at | -0.0453 | 0.8815 | |
| GSE29001 | OTUD3 | 23252 | 213216_at | 0.2121 | 0.4591 | |
| GSE38129 | OTUD3 | 23252 | 213216_at | 0.1221 | 0.4454 | |
| GSE45670 | OTUD3 | 23252 | 213216_at | 0.2514 | 0.2231 | |
| GSE53622 | OTUD3 | 23252 | 75983 | -0.2635 | 0.0433 | |
| GSE53624 | OTUD3 | 23252 | 75983 | 0.0285 | 0.8103 | |
| GSE63941 | OTUD3 | 23252 | 213216_at | 0.3751 | 0.4182 | |
| GSE77861 | OTUD3 | 23252 | 213216_at | 0.1980 | 0.5142 | |
| GSE97050 | OTUD3 | 23252 | A_24_P941188 | -0.3024 | 0.2269 | |
| SRP007169 | OTUD3 | 23252 | RNAseq | 0.1981 | 0.6968 | |
| SRP008496 | OTUD3 | 23252 | RNAseq | 0.7565 | 0.0551 | |
| SRP064894 | OTUD3 | 23252 | RNAseq | 0.1424 | 0.5537 | |
| SRP133303 | OTUD3 | 23252 | RNAseq | 0.3589 | 0.0860 | |
| SRP159526 | OTUD3 | 23252 | RNAseq | 0.5979 | 0.1961 | |
| SRP193095 | OTUD3 | 23252 | RNAseq | 0.1959 | 0.0810 | |
| SRP219564 | OTUD3 | 23252 | RNAseq | 0.1970 | 0.5266 | |
| TCGA | OTUD3 | 23252 | RNAseq | -0.1933 | 0.0118 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OTUD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTUD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OTUD3 | 23252 | 0 | 5 | 25 | |
| GSE20123 | OTUD3 | 23252 | 0 | 4 | 26 | |
| GSE43470 | OTUD3 | 23252 | 0 | 8 | 35 | |
| GSE46452 | OTUD3 | 23252 | 5 | 1 | 53 | |
| GSE47630 | OTUD3 | 23252 | 8 | 3 | 29 | |
| GSE54993 | OTUD3 | 23252 | 3 | 1 | 66 | |
| GSE54994 | OTUD3 | 23252 | 11 | 4 | 38 | |
| GSE60625 | OTUD3 | 23252 | 0 | 0 | 11 | |
| GSE74703 | OTUD3 | 23252 | 0 | 5 | 31 | |
| GSE74704 | OTUD3 | 23252 | 0 | 0 | 20 | |
| TCGA | OTUD3 | 23252 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of OTUD3:
Generating mutation plots.
Highly correlated genes for OTUD3:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTUD3 | GATAD2B | 0.75301 | 3 | 0 | 3 |
| OTUD3 | EDRF1 | 0.747719 | 3 | 0 | 3 |
| OTUD3 | ZNF605 | 0.737424 | 3 | 0 | 3 |
| OTUD3 | WDR35 | 0.72448 | 3 | 0 | 3 |
| OTUD3 | CD3EAP | 0.703937 | 3 | 0 | 3 |
| OTUD3 | MTMR4 | 0.697605 | 3 | 0 | 3 |
| OTUD3 | ZNF614 | 0.68841 | 3 | 0 | 3 |
| OTUD3 | NAPEPLD | 0.688264 | 3 | 0 | 3 |
| OTUD3 | ZNF71 | 0.686756 | 3 | 0 | 3 |
| OTUD3 | KPNA6 | 0.681214 | 4 | 0 | 3 |
| OTUD3 | ZNF391 | 0.678833 | 3 | 0 | 3 |
| OTUD3 | RICTOR | 0.676214 | 3 | 0 | 3 |
| OTUD3 | MSL2 | 0.675615 | 5 | 0 | 4 |
| OTUD3 | WFS1 | 0.672941 | 4 | 0 | 3 |
| OTUD3 | NHLRC2 | 0.670706 | 5 | 0 | 4 |
| OTUD3 | LENG8 | 0.670578 | 4 | 0 | 3 |
| OTUD3 | PDK2 | 0.668807 | 3 | 0 | 3 |
| OTUD3 | MRPS6 | 0.666157 | 3 | 0 | 3 |
| OTUD3 | ZNF121 | 0.66313 | 3 | 0 | 3 |
| OTUD3 | EFEMP2 | 0.659726 | 3 | 0 | 3 |
For details and further investigation, click here
