| Full name: sideroflexin 2 | Alias Symbol: SLC56A2 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 118980 | HGNC ID: HGNC:16086 | Ensembl Gene: ENSG00000156398 | OMIM ID: 615570 |
| Drug and gene relationship at DGIdb | |||
Expression of SFXN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFXN2 | 118980 | 227560_at | 0.2748 | 0.4482 | |
| GSE26886 | SFXN2 | 118980 | 227560_at | 0.0366 | 0.8867 | |
| GSE45670 | SFXN2 | 118980 | 227560_at | -0.0469 | 0.7888 | |
| GSE53622 | SFXN2 | 118980 | 53308 | 0.0328 | 0.8290 | |
| GSE53624 | SFXN2 | 118980 | 13914 | 0.0728 | 0.4441 | |
| GSE63941 | SFXN2 | 118980 | 227560_at | 0.8729 | 0.0406 | |
| GSE77861 | SFXN2 | 118980 | 227560_at | -0.1711 | 0.3095 | |
| GSE97050 | SFXN2 | 118980 | A_24_P175612 | 0.3475 | 0.3363 | |
| SRP007169 | SFXN2 | 118980 | RNAseq | 0.1028 | 0.8519 | |
| SRP064894 | SFXN2 | 118980 | RNAseq | -0.0561 | 0.8023 | |
| SRP133303 | SFXN2 | 118980 | RNAseq | -0.0057 | 0.9658 | |
| SRP159526 | SFXN2 | 118980 | RNAseq | 0.1321 | 0.6229 | |
| SRP193095 | SFXN2 | 118980 | RNAseq | 0.0981 | 0.4968 | |
| SRP219564 | SFXN2 | 118980 | RNAseq | 0.4908 | 0.2429 | |
| TCGA | SFXN2 | 118980 | RNAseq | -0.3247 | 0.0181 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SFXN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFXN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFXN2 | 118980 | 2 | 9 | 19 | |
| GSE20123 | SFXN2 | 118980 | 2 | 8 | 20 | |
| GSE43470 | SFXN2 | 118980 | 0 | 8 | 35 | |
| GSE46452 | SFXN2 | 118980 | 0 | 11 | 48 | |
| GSE47630 | SFXN2 | 118980 | 2 | 14 | 24 | |
| GSE54993 | SFXN2 | 118980 | 8 | 0 | 62 | |
| GSE54994 | SFXN2 | 118980 | 1 | 11 | 41 | |
| GSE60625 | SFXN2 | 118980 | 0 | 0 | 11 | |
| GSE74703 | SFXN2 | 118980 | 0 | 5 | 31 | |
| GSE74704 | SFXN2 | 118980 | 1 | 4 | 15 | |
| TCGA | SFXN2 | 118980 | 5 | 29 | 62 |
Total number of gains: 21; Total number of losses: 99; Total Number of normals: 368.
Somatic mutations of SFXN2:
Generating mutation plots.
Highly correlated genes for SFXN2:
Showing top 20/137 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFXN2 | SNRPC | 0.779418 | 3 | 0 | 3 |
| SFXN2 | CSNK2B | 0.738419 | 3 | 0 | 3 |
| SFXN2 | KIFC1 | 0.731612 | 3 | 0 | 3 |
| SFXN2 | DBF4 | 0.731418 | 3 | 0 | 3 |
| SFXN2 | RAD18 | 0.725415 | 3 | 0 | 3 |
| SFXN2 | ZNF318 | 0.724794 | 3 | 0 | 3 |
| SFXN2 | MTMR4 | 0.710346 | 3 | 0 | 3 |
| SFXN2 | NUP155 | 0.708921 | 3 | 0 | 3 |
| SFXN2 | GLO1 | 0.707357 | 3 | 0 | 3 |
| SFXN2 | USE1 | 0.702505 | 3 | 0 | 3 |
| SFXN2 | NUP133 | 0.698486 | 3 | 0 | 3 |
| SFXN2 | ATAD5 | 0.696452 | 3 | 0 | 3 |
| SFXN2 | SLC25A39 | 0.693798 | 3 | 0 | 3 |
| SFXN2 | SNRPA | 0.692407 | 3 | 0 | 3 |
| SFXN2 | SLC25A19 | 0.688872 | 3 | 0 | 3 |
| SFXN2 | DNA2 | 0.685946 | 3 | 0 | 3 |
| SFXN2 | DPP3 | 0.683091 | 3 | 0 | 3 |
| SFXN2 | PCGF5 | 0.680141 | 3 | 0 | 3 |
| SFXN2 | GPS1 | 0.678211 | 3 | 0 | 3 |
| SFXN2 | TGIF2 | 0.67798 | 3 | 0 | 3 |
For details and further investigation, click here
