| Full name: rhomboid domain containing 2 | Alias Symbol: NPD007 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 57414 | HGNC ID: HGNC:23082 | Ensembl Gene: ENSG00000005486 | OMIM ID: 615203 |
| Drug and gene relationship at DGIdb | |||
Expression of RHBDD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHBDD2 | 57414 | 222995_s_at | 0.6040 | 0.2157 | |
| GSE26886 | RHBDD2 | 57414 | 222995_s_at | 0.7242 | 0.0010 | |
| GSE45670 | RHBDD2 | 57414 | 222995_s_at | 0.6215 | 0.0048 | |
| GSE53622 | RHBDD2 | 57414 | 84272 | 0.7763 | 0.0000 | |
| GSE53624 | RHBDD2 | 57414 | 84272 | 0.8766 | 0.0000 | |
| GSE63941 | RHBDD2 | 57414 | 222995_s_at | 0.2106 | 0.7316 | |
| GSE77861 | RHBDD2 | 57414 | 222995_s_at | 0.5822 | 0.0905 | |
| GSE97050 | RHBDD2 | 57414 | A_23_P8561 | 0.6322 | 0.1818 | |
| SRP007169 | RHBDD2 | 57414 | RNAseq | 0.0980 | 0.7796 | |
| SRP008496 | RHBDD2 | 57414 | RNAseq | 0.6885 | 0.0364 | |
| SRP064894 | RHBDD2 | 57414 | RNAseq | 0.8458 | 0.0025 | |
| SRP133303 | RHBDD2 | 57414 | RNAseq | 0.7170 | 0.0013 | |
| SRP159526 | RHBDD2 | 57414 | RNAseq | 0.8726 | 0.0101 | |
| SRP193095 | RHBDD2 | 57414 | RNAseq | 0.7194 | 0.0000 | |
| SRP219564 | RHBDD2 | 57414 | RNAseq | 0.6361 | 0.0958 | |
| TCGA | RHBDD2 | 57414 | RNAseq | 0.1399 | 0.0100 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RHBDD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHBDD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHBDD2 | 57414 | 14 | 1 | 15 | |
| GSE20123 | RHBDD2 | 57414 | 14 | 1 | 15 | |
| GSE43470 | RHBDD2 | 57414 | 3 | 2 | 38 | |
| GSE46452 | RHBDD2 | 57414 | 12 | 0 | 47 | |
| GSE47630 | RHBDD2 | 57414 | 7 | 2 | 31 | |
| GSE54993 | RHBDD2 | 57414 | 2 | 7 | 61 | |
| GSE54994 | RHBDD2 | 57414 | 14 | 3 | 36 | |
| GSE60625 | RHBDD2 | 57414 | 0 | 0 | 11 | |
| GSE74703 | RHBDD2 | 57414 | 3 | 1 | 32 | |
| GSE74704 | RHBDD2 | 57414 | 8 | 1 | 11 | |
| TCGA | RHBDD2 | 57414 | 44 | 5 | 47 |
Total number of gains: 121; Total number of losses: 23; Total Number of normals: 344.
Somatic mutations of RHBDD2:
Generating mutation plots.
Highly correlated genes for RHBDD2:
Showing top 20/1805 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHBDD2 | LGALS8 | 0.833549 | 3 | 0 | 3 |
| RHBDD2 | USP34 | 0.805659 | 3 | 0 | 3 |
| RHBDD2 | YIPF3 | 0.792793 | 3 | 0 | 3 |
| RHBDD2 | C12orf73 | 0.769418 | 3 | 0 | 3 |
| RHBDD2 | CHAF1B | 0.766485 | 4 | 0 | 4 |
| RHBDD2 | L3MBTL3 | 0.765655 | 3 | 0 | 3 |
| RHBDD2 | NSD1 | 0.764261 | 3 | 0 | 3 |
| RHBDD2 | ANKRD16 | 0.760283 | 3 | 0 | 3 |
| RHBDD2 | MTMR4 | 0.751871 | 3 | 0 | 3 |
| RHBDD2 | CD200 | 0.750382 | 3 | 0 | 3 |
| RHBDD2 | PDIA4 | 0.745107 | 6 | 0 | 6 |
| RHBDD2 | MIF | 0.744264 | 3 | 0 | 3 |
| RHBDD2 | LSM4 | 0.743902 | 5 | 0 | 5 |
| RHBDD2 | DHX40 | 0.743599 | 3 | 0 | 3 |
| RHBDD2 | ASPSCR1 | 0.743128 | 5 | 0 | 5 |
| RHBDD2 | TNFRSF1A | 0.741639 | 3 | 0 | 3 |
| RHBDD2 | DNMT1 | 0.739806 | 7 | 0 | 7 |
| RHBDD2 | PYCR2 | 0.738173 | 3 | 0 | 3 |
| RHBDD2 | PPP5C | 0.736583 | 4 | 0 | 3 |
| RHBDD2 | SMARCD2 | 0.736563 | 3 | 0 | 3 |
For details and further investigation, click here
