| Full name: semaphorin 5B | Alias Symbol: SemG|KIAA1445|FLJ10372 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 54437 | HGNC ID: HGNC:10737 | Ensembl Gene: ENSG00000082684 | OMIM ID: 609298 |
| Drug and gene relationship at DGIdb | |||
Expression of SEMA5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEMA5B | 54437 | 223610_at | -0.1896 | 0.4002 | |
| GSE26886 | SEMA5B | 54437 | 223610_at | 0.0142 | 0.9666 | |
| GSE45670 | SEMA5B | 54437 | 223610_at | 0.0165 | 0.9029 | |
| GSE53622 | SEMA5B | 54437 | 74655 | 0.2384 | 0.1707 | |
| GSE53624 | SEMA5B | 54437 | 80936 | 0.5476 | 0.0001 | |
| GSE63941 | SEMA5B | 54437 | 223610_at | 0.5261 | 0.1283 | |
| GSE77861 | SEMA5B | 54437 | 223610_at | -0.1742 | 0.0819 | |
| GSE97050 | SEMA5B | 54437 | A_33_P3365228 | 0.3785 | 0.2472 | |
| SRP133303 | SEMA5B | 54437 | RNAseq | 0.8159 | 0.1058 | |
| SRP159526 | SEMA5B | 54437 | RNAseq | 0.9630 | 0.0857 | |
| SRP219564 | SEMA5B | 54437 | RNAseq | 0.5303 | 0.5047 | |
| TCGA | SEMA5B | 54437 | RNAseq | 1.0818 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SEMA5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEMA5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEMA5B | 54437 | 18 | 0 | 12 | |
| GSE20123 | SEMA5B | 54437 | 18 | 0 | 12 | |
| GSE43470 | SEMA5B | 54437 | 20 | 0 | 23 | |
| GSE46452 | SEMA5B | 54437 | 14 | 5 | 40 | |
| GSE47630 | SEMA5B | 54437 | 17 | 4 | 19 | |
| GSE54993 | SEMA5B | 54437 | 2 | 7 | 61 | |
| GSE54994 | SEMA5B | 54437 | 30 | 4 | 19 | |
| GSE60625 | SEMA5B | 54437 | 0 | 6 | 5 | |
| GSE74703 | SEMA5B | 54437 | 16 | 0 | 20 | |
| GSE74704 | SEMA5B | 54437 | 13 | 0 | 7 | |
| TCGA | SEMA5B | 54437 | 54 | 6 | 36 |
Total number of gains: 202; Total number of losses: 32; Total Number of normals: 254.
Somatic mutations of SEMA5B:
Generating mutation plots.
Highly correlated genes for SEMA5B:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEMA5B | TESC | 0.776505 | 3 | 0 | 3 |
| SEMA5B | ADRA2A | 0.767734 | 3 | 0 | 3 |
| SEMA5B | LRRC3 | 0.757627 | 3 | 0 | 3 |
| SEMA5B | MYO18B | 0.750218 | 3 | 0 | 3 |
| SEMA5B | ESAM | 0.745427 | 3 | 0 | 3 |
| SEMA5B | C22orf23 | 0.736975 | 3 | 0 | 3 |
| SEMA5B | SLC34A3 | 0.735172 | 3 | 0 | 3 |
| SEMA5B | CAPN13 | 0.723665 | 4 | 0 | 4 |
| SEMA5B | PRSS54 | 0.695566 | 3 | 0 | 3 |
| SEMA5B | SLC37A1 | 0.692182 | 3 | 0 | 3 |
| SEMA5B | CCDC157 | 0.686459 | 3 | 0 | 3 |
| SEMA5B | SMOC1 | 0.678869 | 5 | 0 | 4 |
| SEMA5B | CNGB3 | 0.673919 | 3 | 0 | 3 |
| SEMA5B | CABP4 | 0.6736 | 4 | 0 | 3 |
| SEMA5B | GRID1 | 0.670104 | 3 | 0 | 3 |
| SEMA5B | PRSS33 | 0.669629 | 3 | 0 | 3 |
| SEMA5B | TUSC1 | 0.656295 | 3 | 0 | 3 |
| SEMA5B | TTC39A | 0.653729 | 3 | 0 | 3 |
| SEMA5B | SUN2 | 0.649548 | 3 | 0 | 3 |
| SEMA5B | SIRPD | 0.643929 | 4 | 0 | 4 |
For details and further investigation, click here
