FGF17

 

Full name: fibroblast growth factor 17 Alias Symbol: FGF-13
Type: protein-coding gene Cytoband: 8p21.3
Entrez ID: 8822 HGNC ID: HGNC:3673 Ensembl Gene: ENSG00000158815 OMIM ID: 603725
Drug and gene relationship at DGIdb

 

FGF17 involved pathways:

KEGG pathway Description View
hsa04010MAPK signaling pathway
hsa04014Ras signaling pathway
hsa04015Rap1 signaling pathway
hsa04151PI3K-Akt signaling pathway
hsa05200Pathways in cancer
hsa05218Melanoma

 

Expression of FGF17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FGF17 8822 221376_at -0.0300 0.9339
GSE20347 FGF17 8822 221376_at 0.0028 0.9730
GSE23400 FGF17 8822 221376_at -0.0492 0.1353
GSE26886 FGF17 8822 221376_at 0.1755 0.2692
GSE29001 FGF17 8822 221376_at -0.1212 0.2809
GSE38129 FGF17 8822 221376_at -0.0470 0.5522
GSE45670 FGF17 8822 221376_at 0.0184 0.8587
GSE53622 FGF17 8822 53723 0.2168 0.0005
GSE53624 FGF17 8822 53723 0.3256 0.0000
GSE63941 FGF17 8822 221376_at 0.3570 0.0341
GSE77861 FGF17 8822 221376_at -0.1151 0.3452
GSE97050 FGF17 8822 A_23_P429363 -0.0854 0.7032
TCGA FGF17 8822 RNAseq -0.3807 0.4789

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by FGF17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FGF17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FGF17 8822 4 10 16
GSE20123 FGF17 8822 4 10 16
GSE43470 FGF17 8822 4 9 30
GSE46452 FGF17 8822 13 13 33
GSE47630 FGF17 8822 10 8 22
GSE54993 FGF17 8822 2 14 54
GSE54994 FGF17 8822 8 18 27
GSE60625 FGF17 8822 3 0 8
GSE74703 FGF17 8822 4 7 25
GSE74704 FGF17 8822 3 7 10
TCGA FGF17 8822 13 43 40

Total number of gains: 68; Total number of losses: 139; Total Number of normals: 281.  


 

Somatic mutations of FGF17:

 

Generating mutation plots.

 

Highly correlated genes for FGF17:

 

Showing top 20/869 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FGF17PRRG30.815669303
FGF17CLEC4G0.77268303
FGF17DCD0.759569303
FGF17MYO18B0.756768303
FGF17SCAMP50.754336303
FGF17TTLL90.749334303
FGF17DHH0.748747303
FGF17PSMB110.742574303
FGF17IGFN10.730977403
FGF17PROC0.728367303
FGF17OR5A10.727825303
FGF17CATSPER30.725263303
FGF17ARL4D0.722475303
FGF17UFSP10.720089303
FGF17PGLYRP20.71699303
FGF17IL17RE0.714104303
FGF17REG3G0.713163303
FGF17LRRN40.711254303
FGF17PHOSPHO10.70647403
FGF17HSPA12B0.704752303

For details and further investigation, click here