| Full name: neural cell adhesion molecule 2 | Alias Symbol: NCAM21|MGC51008 | ||
| Type: protein-coding gene | Cytoband: 21q21.1 | ||
| Entrez ID: 4685 | HGNC ID: HGNC:7657 | Ensembl Gene: ENSG00000154654 | OMIM ID: 602040 |
| Drug and gene relationship at DGIdb | |||
NCAM2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05020 | Prion diseases |
Expression of NCAM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCAM2 | 4685 | 205669_at | -0.2004 | 0.4425 | |
| GSE20347 | NCAM2 | 4685 | 205669_at | 0.0986 | 0.1446 | |
| GSE23400 | NCAM2 | 4685 | 205669_at | -0.0778 | 0.0333 | |
| GSE26886 | NCAM2 | 4685 | 205669_at | -0.0112 | 0.9124 | |
| GSE29001 | NCAM2 | 4685 | 205669_at | 0.1192 | 0.2841 | |
| GSE38129 | NCAM2 | 4685 | 205669_at | 0.0153 | 0.8232 | |
| GSE45670 | NCAM2 | 4685 | 205669_at | -0.0741 | 0.3988 | |
| GSE53622 | NCAM2 | 4685 | 10183 | -0.5498 | 0.0216 | |
| GSE53624 | NCAM2 | 4685 | 10183 | -0.1858 | 0.3593 | |
| GSE63941 | NCAM2 | 4685 | 205669_at | -1.2272 | 0.0118 | |
| GSE77861 | NCAM2 | 4685 | 205669_at | -0.0443 | 0.5737 | |
| GSE97050 | NCAM2 | 4685 | A_33_P3239884 | -0.1551 | 0.6015 | |
| SRP007169 | NCAM2 | 4685 | RNAseq | 2.8308 | 0.0003 | |
| SRP008496 | NCAM2 | 4685 | RNAseq | 3.7569 | 0.0000 | |
| SRP133303 | NCAM2 | 4685 | RNAseq | 0.9760 | 0.0042 | |
| SRP159526 | NCAM2 | 4685 | RNAseq | 1.8500 | 0.0104 | |
| SRP219564 | NCAM2 | 4685 | RNAseq | -0.0087 | 0.9909 | |
| TCGA | NCAM2 | 4685 | RNAseq | -0.5315 | 0.2560 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by NCAM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCAM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCAM2 | 4685 | 0 | 13 | 17 | |
| GSE20123 | NCAM2 | 4685 | 0 | 13 | 17 | |
| GSE43470 | NCAM2 | 4685 | 1 | 11 | 31 | |
| GSE46452 | NCAM2 | 4685 | 1 | 21 | 37 | |
| GSE47630 | NCAM2 | 4685 | 6 | 17 | 17 | |
| GSE54993 | NCAM2 | 4685 | 9 | 2 | 59 | |
| GSE54994 | NCAM2 | 4685 | 3 | 10 | 40 | |
| GSE60625 | NCAM2 | 4685 | 0 | 0 | 11 | |
| GSE74703 | NCAM2 | 4685 | 1 | 8 | 27 | |
| GSE74704 | NCAM2 | 4685 | 0 | 9 | 11 | |
| TCGA | NCAM2 | 4685 | 8 | 40 | 48 |
Total number of gains: 29; Total number of losses: 144; Total Number of normals: 315.
Somatic mutations of NCAM2:
Generating mutation plots.
Highly correlated genes for NCAM2:
Showing top 20/163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCAM2 | LINC00968 | 0.692177 | 3 | 0 | 3 |
| NCAM2 | RNASE1 | 0.686583 | 3 | 0 | 3 |
| NCAM2 | LAMB2 | 0.68476 | 4 | 0 | 4 |
| NCAM2 | TCEAL7 | 0.680402 | 5 | 0 | 5 |
| NCAM2 | DACT3 | 0.676044 | 5 | 0 | 5 |
| NCAM2 | ZBTB47 | 0.672063 | 3 | 0 | 3 |
| NCAM2 | OMD | 0.66955 | 5 | 0 | 4 |
| NCAM2 | C1QTNF2 | 0.661527 | 3 | 0 | 3 |
| NCAM2 | SGCB | 0.651577 | 3 | 0 | 3 |
| NCAM2 | SMIM10 | 0.648468 | 4 | 0 | 4 |
| NCAM2 | SGCD | 0.647474 | 5 | 0 | 5 |
| NCAM2 | NAP1L3 | 0.646714 | 5 | 0 | 4 |
| NCAM2 | SLC25A4 | 0.644908 | 4 | 0 | 3 |
| NCAM2 | CYS1 | 0.643709 | 4 | 0 | 3 |
| NCAM2 | SMPX | 0.637588 | 3 | 0 | 3 |
| NCAM2 | NRK | 0.637559 | 6 | 0 | 5 |
| NCAM2 | SSPN | 0.636476 | 4 | 0 | 3 |
| NCAM2 | OGN | 0.636211 | 4 | 0 | 4 |
| NCAM2 | MAGI2-AS3 | 0.626703 | 4 | 0 | 4 |
| NCAM2 | GRIN2A | 0.625633 | 4 | 0 | 3 |
For details and further investigation, click here
