| Full name: sarcoglycan beta | Alias Symbol: SGC|A3b | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 6443 | HGNC ID: HGNC:10806 | Ensembl Gene: ENSG00000163069 | OMIM ID: 600900 |
| Drug and gene relationship at DGIdb | |||
Expression of SGCB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SGCB | 6443 | 226112_at | -0.6545 | 0.3672 | |
| GSE20347 | SGCB | 6443 | 205120_s_at | 0.2475 | 0.1961 | |
| GSE23400 | SGCB | 6443 | 205120_s_at | 0.3982 | 0.0009 | |
| GSE26886 | SGCB | 6443 | 205120_s_at | 0.6205 | 0.0153 | |
| GSE29001 | SGCB | 6443 | 205120_s_at | 0.6384 | 0.1815 | |
| GSE38129 | SGCB | 6443 | 205120_s_at | 0.3080 | 0.2680 | |
| GSE45670 | SGCB | 6443 | 226112_at | -0.9574 | 0.0009 | |
| GSE53622 | SGCB | 6443 | 120924 | -0.4904 | 0.0005 | |
| GSE53624 | SGCB | 6443 | 120924 | -0.2034 | 0.0768 | |
| GSE63941 | SGCB | 6443 | 205120_s_at | -2.6792 | 0.0184 | |
| GSE77861 | SGCB | 6443 | 205120_s_at | 0.4148 | 0.1055 | |
| GSE97050 | SGCB | 6443 | A_33_P3357843 | -0.9938 | 0.1143 | |
| SRP007169 | SGCB | 6443 | RNAseq | 1.6219 | 0.0002 | |
| SRP008496 | SGCB | 6443 | RNAseq | 3.3727 | 0.0000 | |
| SRP064894 | SGCB | 6443 | RNAseq | 0.3983 | 0.0570 | |
| SRP133303 | SGCB | 6443 | RNAseq | 0.5202 | 0.0704 | |
| SRP159526 | SGCB | 6443 | RNAseq | -0.1489 | 0.3698 | |
| SRP193095 | SGCB | 6443 | RNAseq | 0.4393 | 0.0435 | |
| SRP219564 | SGCB | 6443 | RNAseq | -0.4416 | 0.5757 | |
| TCGA | SGCB | 6443 | RNAseq | -0.3044 | 0.0009 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by SGCB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SGCB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SGCB | 6443 | 4 | 11 | 15 | |
| GSE20123 | SGCB | 6443 | 3 | 11 | 16 | |
| GSE43470 | SGCB | 6443 | 0 | 14 | 29 | |
| GSE46452 | SGCB | 6443 | 1 | 36 | 22 | |
| GSE47630 | SGCB | 6443 | 1 | 18 | 21 | |
| GSE54993 | SGCB | 6443 | 7 | 0 | 63 | |
| GSE54994 | SGCB | 6443 | 2 | 10 | 41 | |
| GSE60625 | SGCB | 6443 | 0 | 0 | 11 | |
| GSE74703 | SGCB | 6443 | 0 | 12 | 24 | |
| GSE74704 | SGCB | 6443 | 2 | 6 | 12 | |
| TCGA | SGCB | 6443 | 17 | 29 | 50 |
Total number of gains: 37; Total number of losses: 147; Total Number of normals: 304.
Somatic mutations of SGCB:
Generating mutation plots.
Highly correlated genes for SGCB:
Showing top 20/1215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SGCB | TCEAL6 | 0.844421 | 3 | 0 | 3 |
| SGCB | ZEB1 | 0.80621 | 3 | 0 | 3 |
| SGCB | TNFSF12 | 0.794648 | 3 | 0 | 3 |
| SGCB | ERRFI1 | 0.757705 | 4 | 0 | 4 |
| SGCB | C20orf194 | 0.755835 | 4 | 0 | 4 |
| SGCB | CORO6 | 0.749001 | 3 | 0 | 3 |
| SGCB | MYADM | 0.747779 | 4 | 0 | 4 |
| SGCB | RHOJ | 0.746691 | 4 | 0 | 4 |
| SGCB | TOB2 | 0.746179 | 3 | 0 | 3 |
| SGCB | LRCH2 | 0.745233 | 7 | 0 | 7 |
| SGCB | GNPDA2 | 0.744242 | 5 | 0 | 5 |
| SGCB | MYL6B | 0.743978 | 3 | 0 | 3 |
| SGCB | FNDC5 | 0.735413 | 4 | 0 | 4 |
| SGCB | CELF6 | 0.734036 | 3 | 0 | 3 |
| SGCB | TCEAL5 | 0.730826 | 3 | 0 | 3 |
| SGCB | KCNE3 | 0.729812 | 3 | 0 | 3 |
| SGCB | HMCN1 | 0.729216 | 8 | 0 | 8 |
| SGCB | MSRB3 | 0.727147 | 7 | 0 | 6 |
| SGCB | MYOCD | 0.726569 | 5 | 0 | 5 |
| SGCB | NAPEPLD | 0.726494 | 3 | 0 | 3 |
For details and further investigation, click here
