| Full name: glutamate ionotropic receptor NMDA type subunit 2A | Alias Symbol: GluN2A | ||
| Type: protein-coding gene | Cytoband: 16p13.2 | ||
| Entrez ID: 2903 | HGNC ID: HGNC:4585 | Ensembl Gene: ENSG00000183454 | OMIM ID: 138253 |
| Drug and gene relationship at DGIdb | |||
GRIN2A involved pathways:
Expression of GRIN2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRIN2A | 2903 | 206534_at | -0.3835 | 0.4772 | |
| GSE20347 | GRIN2A | 2903 | 206534_at | -0.0682 | 0.4419 | |
| GSE23400 | GRIN2A | 2903 | 206534_at | -0.2001 | 0.0000 | |
| GSE26886 | GRIN2A | 2903 | 206534_at | -0.2468 | 0.0094 | |
| GSE29001 | GRIN2A | 2903 | 206534_at | -0.3206 | 0.0577 | |
| GSE38129 | GRIN2A | 2903 | 206534_at | -0.1684 | 0.0734 | |
| GSE45670 | GRIN2A | 2903 | 206534_at | -0.1620 | 0.0761 | |
| GSE53622 | GRIN2A | 2903 | 26806 | -1.0890 | 0.0000 | |
| GSE53624 | GRIN2A | 2903 | 26806 | -0.1107 | 0.0757 | |
| GSE63941 | GRIN2A | 2903 | 206534_at | 0.2443 | 0.2486 | |
| GSE77861 | GRIN2A | 2903 | 206534_at | -0.0513 | 0.6582 | |
| GSE97050 | GRIN2A | 2903 | A_33_P3334895 | -0.3994 | 0.5043 | |
| SRP064894 | GRIN2A | 2903 | RNAseq | -1.7099 | 0.0000 | |
| SRP133303 | GRIN2A | 2903 | RNAseq | -1.2230 | 0.0027 | |
| SRP159526 | GRIN2A | 2903 | RNAseq | -2.8943 | 0.0000 | |
| SRP193095 | GRIN2A | 2903 | RNAseq | -0.6755 | 0.0231 | |
| SRP219564 | GRIN2A | 2903 | RNAseq | -0.2248 | 0.8067 | |
| TCGA | GRIN2A | 2903 | RNAseq | -1.5814 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by GRIN2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRIN2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRIN2A | 2903 | 4 | 3 | 23 | |
| GSE20123 | GRIN2A | 2903 | 4 | 2 | 24 | |
| GSE43470 | GRIN2A | 2903 | 3 | 3 | 37 | |
| GSE46452 | GRIN2A | 2903 | 38 | 1 | 20 | |
| GSE47630 | GRIN2A | 2903 | 13 | 6 | 21 | |
| GSE54993 | GRIN2A | 2903 | 3 | 5 | 62 | |
| GSE54994 | GRIN2A | 2903 | 5 | 9 | 39 | |
| GSE60625 | GRIN2A | 2903 | 4 | 0 | 7 | |
| GSE74703 | GRIN2A | 2903 | 3 | 2 | 31 | |
| GSE74704 | GRIN2A | 2903 | 2 | 1 | 17 | |
| TCGA | GRIN2A | 2903 | 19 | 13 | 64 |
Total number of gains: 98; Total number of losses: 45; Total Number of normals: 345.
Somatic mutations of GRIN2A:
Generating mutation plots.
Highly correlated genes for GRIN2A:
Showing top 20/791 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRIN2A | CHRNB2 | 0.737762 | 3 | 0 | 3 |
| GRIN2A | GKAP1 | 0.733102 | 3 | 0 | 3 |
| GRIN2A | NACAD | 0.727728 | 4 | 0 | 4 |
| GRIN2A | GPR146 | 0.716467 | 3 | 0 | 3 |
| GRIN2A | OR2H2 | 0.703462 | 6 | 0 | 6 |
| GRIN2A | OR10H3 | 0.697236 | 7 | 0 | 7 |
| GRIN2A | MUC3B | 0.693254 | 4 | 0 | 4 |
| GRIN2A | RGS5 | 0.692399 | 3 | 0 | 3 |
| GRIN2A | KRT76 | 0.687611 | 4 | 0 | 3 |
| GRIN2A | FSCN3 | 0.684146 | 5 | 0 | 5 |
| GRIN2A | KHDRBS2 | 0.680826 | 5 | 0 | 4 |
| GRIN2A | ASIC4 | 0.677657 | 6 | 0 | 5 |
| GRIN2A | PRDM11 | 0.67721 | 5 | 0 | 5 |
| GRIN2A | CAP2 | 0.676894 | 3 | 0 | 3 |
| GRIN2A | AKAP6 | 0.675722 | 7 | 0 | 6 |
| GRIN2A | AMHR2 | 0.674199 | 7 | 0 | 7 |
| GRIN2A | ENPP6 | 0.673154 | 3 | 0 | 3 |
| GRIN2A | PRR26 | 0.668637 | 3 | 0 | 3 |
| GRIN2A | IL1RAPL2 | 0.668174 | 6 | 0 | 6 |
| GRIN2A | GNAT1 | 0.668126 | 5 | 0 | 5 |
For details and further investigation, click here
