| Full name: sarcospan | Alias Symbol: SPN1|SPN2 | ||
| Type: protein-coding gene | Cytoband: 12p11.2 | ||
| Entrez ID: 8082 | HGNC ID: HGNC:11322 | Ensembl Gene: ENSG00000123096 | OMIM ID: 601599 |
| Drug and gene relationship at DGIdb | |||
Expression of SSPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSPN | 8082 | 204963_at | -1.0267 | 0.3277 | |
| GSE20347 | SSPN | 8082 | 204964_s_at | 0.2432 | 0.2508 | |
| GSE23400 | SSPN | 8082 | 204964_s_at | -0.1068 | 0.4008 | |
| GSE26886 | SSPN | 8082 | 204963_at | 2.0173 | 0.0003 | |
| GSE29001 | SSPN | 8082 | 204964_s_at | 0.5915 | 0.1224 | |
| GSE38129 | SSPN | 8082 | 204963_at | -0.4867 | 0.3523 | |
| GSE45670 | SSPN | 8082 | 226932_at | -2.1518 | 0.0001 | |
| GSE53622 | SSPN | 8082 | 56416 | -0.0108 | 0.9539 | |
| GSE53624 | SSPN | 8082 | 56416 | -0.2662 | 0.0530 | |
| GSE63941 | SSPN | 8082 | 226932_at | -3.9271 | 0.0052 | |
| GSE77861 | SSPN | 8082 | 204964_s_at | 0.0560 | 0.6185 | |
| GSE97050 | SSPN | 8082 | A_23_P203920 | -0.5627 | 0.2816 | |
| SRP007169 | SSPN | 8082 | RNAseq | 0.8274 | 0.1377 | |
| SRP008496 | SSPN | 8082 | RNAseq | 2.2982 | 0.0001 | |
| SRP064894 | SSPN | 8082 | RNAseq | -0.2300 | 0.4338 | |
| SRP133303 | SSPN | 8082 | RNAseq | 0.3294 | 0.2688 | |
| SRP159526 | SSPN | 8082 | RNAseq | -0.7655 | 0.0537 | |
| SRP193095 | SSPN | 8082 | RNAseq | 0.4415 | 0.0366 | |
| SRP219564 | SSPN | 8082 | RNAseq | -0.4961 | 0.5618 | |
| TCGA | SSPN | 8082 | RNAseq | -0.1861 | 0.1586 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by SSPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSPN | 8082 | 10 | 1 | 19 | |
| GSE20123 | SSPN | 8082 | 10 | 1 | 19 | |
| GSE43470 | SSPN | 8082 | 9 | 4 | 30 | |
| GSE46452 | SSPN | 8082 | 10 | 1 | 48 | |
| GSE47630 | SSPN | 8082 | 14 | 0 | 26 | |
| GSE54993 | SSPN | 8082 | 0 | 9 | 61 | |
| GSE54994 | SSPN | 8082 | 11 | 2 | 40 | |
| GSE60625 | SSPN | 8082 | 0 | 1 | 10 | |
| GSE74703 | SSPN | 8082 | 9 | 3 | 24 | |
| GSE74704 | SSPN | 8082 | 6 | 1 | 13 | |
| TCGA | SSPN | 8082 | 44 | 5 | 47 |
Total number of gains: 123; Total number of losses: 28; Total Number of normals: 337.
Somatic mutations of SSPN:
Generating mutation plots.
Highly correlated genes for SSPN:
Showing top 20/1171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSPN | FIBIN | 0.781347 | 4 | 0 | 4 |
| SSPN | ZEB1 | 0.775321 | 3 | 0 | 3 |
| SSPN | EPHA3 | 0.754503 | 6 | 0 | 6 |
| SSPN | TBX5 | 0.742239 | 7 | 0 | 7 |
| SSPN | MADD | 0.73776 | 3 | 0 | 3 |
| SSPN | MRGPRF | 0.735589 | 8 | 0 | 8 |
| SSPN | PITPNM2 | 0.734663 | 3 | 0 | 3 |
| SSPN | SYNC | 0.732276 | 7 | 0 | 6 |
| SSPN | ANGPT1 | 0.729238 | 9 | 0 | 8 |
| SSPN | MGARP | 0.726868 | 3 | 0 | 3 |
| SSPN | PARVA | 0.726583 | 10 | 0 | 10 |
| SSPN | P2RX1 | 0.726299 | 3 | 0 | 3 |
| SSPN | MRVI1 | 0.722732 | 6 | 0 | 5 |
| SSPN | RASSF8 | 0.721057 | 7 | 0 | 7 |
| SSPN | ZNF132 | 0.720739 | 3 | 0 | 3 |
| SSPN | SGCD | 0.72042 | 9 | 0 | 8 |
| SSPN | MACROD2 | 0.719235 | 3 | 0 | 3 |
| SSPN | AGTR1 | 0.708951 | 8 | 0 | 8 |
| SSPN | MCAM | 0.707458 | 8 | 0 | 7 |
| SSPN | PABPC5 | 0.707446 | 5 | 0 | 5 |
For details and further investigation, click here
