| Full name: nuclear distribution C, dynein complex regulator | Alias Symbol: NudC | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 10726 | HGNC ID: HGNC:8045 | Ensembl Gene: ENSG00000090273 | OMIM ID: 610325 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUDC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDC | 10726 | 201173_x_at | 0.2384 | 0.3378 | |
| GSE20347 | NUDC | 10726 | 201173_x_at | 0.5070 | 0.0000 | |
| GSE23400 | NUDC | 10726 | 201173_x_at | 0.3173 | 0.0000 | |
| GSE26886 | NUDC | 10726 | 201173_x_at | 0.4674 | 0.0152 | |
| GSE29001 | NUDC | 10726 | 201173_x_at | 0.6210 | 0.0074 | |
| GSE38129 | NUDC | 10726 | 201173_x_at | 0.3808 | 0.0006 | |
| GSE45670 | NUDC | 10726 | 201173_x_at | 0.2828 | 0.1110 | |
| GSE53622 | NUDC | 10726 | 29085 | 0.2404 | 0.0000 | |
| GSE53624 | NUDC | 10726 | 29085 | 0.5019 | 0.0000 | |
| GSE63941 | NUDC | 10726 | 201173_x_at | -0.0201 | 0.9569 | |
| GSE77861 | NUDC | 10726 | 210574_s_at | 0.2517 | 0.0455 | |
| GSE97050 | NUDC | 10726 | A_23_P74653 | -0.1055 | 0.6793 | |
| SRP007169 | NUDC | 10726 | RNAseq | 0.7254 | 0.0846 | |
| SRP008496 | NUDC | 10726 | RNAseq | 0.7630 | 0.0232 | |
| SRP064894 | NUDC | 10726 | RNAseq | 0.8409 | 0.0081 | |
| SRP133303 | NUDC | 10726 | RNAseq | 0.5880 | 0.0002 | |
| SRP159526 | NUDC | 10726 | RNAseq | 0.7048 | 0.0239 | |
| SRP193095 | NUDC | 10726 | RNAseq | 0.4344 | 0.0003 | |
| SRP219564 | NUDC | 10726 | RNAseq | 0.2075 | 0.6163 | |
| TCGA | NUDC | 10726 | RNAseq | 0.0036 | 0.9394 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUDC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDC | 10726 | 0 | 6 | 24 | |
| GSE20123 | NUDC | 10726 | 0 | 5 | 25 | |
| GSE43470 | NUDC | 10726 | 2 | 6 | 35 | |
| GSE46452 | NUDC | 10726 | 5 | 1 | 53 | |
| GSE47630 | NUDC | 10726 | 8 | 3 | 29 | |
| GSE54993 | NUDC | 10726 | 2 | 1 | 67 | |
| GSE54994 | NUDC | 10726 | 10 | 4 | 39 | |
| GSE60625 | NUDC | 10726 | 0 | 0 | 11 | |
| GSE74703 | NUDC | 10726 | 1 | 4 | 31 | |
| GSE74704 | NUDC | 10726 | 0 | 0 | 20 | |
| TCGA | NUDC | 10726 | 10 | 24 | 62 |
Total number of gains: 38; Total number of losses: 54; Total Number of normals: 396.
Somatic mutations of NUDC:
Generating mutation plots.
Highly correlated genes for NUDC:
Showing top 20/1730 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDC | PEG10 | 0.798499 | 3 | 0 | 3 |
| NUDC | PTGS2 | 0.762485 | 3 | 0 | 3 |
| NUDC | CERK | 0.761895 | 3 | 0 | 3 |
| NUDC | SOCS7 | 0.75785 | 3 | 0 | 3 |
| NUDC | RAB34 | 0.724092 | 3 | 0 | 3 |
| NUDC | SLC35B2 | 0.719397 | 3 | 0 | 3 |
| NUDC | ZNF703 | 0.716092 | 3 | 0 | 3 |
| NUDC | JKAMP | 0.714275 | 4 | 0 | 4 |
| NUDC | EEF1D | 0.713604 | 6 | 0 | 6 |
| NUDC | PFDN2 | 0.703156 | 11 | 0 | 11 |
| NUDC | WDR81 | 0.702924 | 3 | 0 | 3 |
| NUDC | TUBA1B | 0.700135 | 9 | 0 | 8 |
| NUDC | TMEM60 | 0.699808 | 3 | 0 | 3 |
| NUDC | MRPS26 | 0.699259 | 5 | 0 | 5 |
| NUDC | C9orf64 | 0.699117 | 3 | 0 | 3 |
| NUDC | TRIB1 | 0.697103 | 4 | 0 | 4 |
| NUDC | PALB2 | 0.692327 | 4 | 0 | 3 |
| NUDC | ZBTB11 | 0.688446 | 3 | 0 | 3 |
| NUDC | DZIP3 | 0.687168 | 4 | 0 | 3 |
| NUDC | CHURC1 | 0.683993 | 3 | 0 | 3 |
For details and further investigation, click here
