| Full name: solute carrier family 35 member B2 | Alias Symbol: UGTrel4 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 347734 | HGNC ID: HGNC:16872 | Ensembl Gene: ENSG00000157593 | OMIM ID: 610788 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SLC35B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SLC35B2 | 347734 | 68373 | 0.7297 | 0.0000 | |
| GSE53624 | SLC35B2 | 347734 | 68373 | 1.1084 | 0.0000 | |
| GSE97050 | SLC35B2 | 347734 | A_33_P3368039 | 0.3050 | 0.2233 | |
| SRP007169 | SLC35B2 | 347734 | RNAseq | 1.0458 | 0.0094 | |
| SRP008496 | SLC35B2 | 347734 | RNAseq | 1.1948 | 0.0000 | |
| SRP064894 | SLC35B2 | 347734 | RNAseq | 1.1650 | 0.0000 | |
| SRP133303 | SLC35B2 | 347734 | RNAseq | 0.8027 | 0.0001 | |
| SRP159526 | SLC35B2 | 347734 | RNAseq | 0.9020 | 0.0000 | |
| SRP193095 | SLC35B2 | 347734 | RNAseq | 0.6477 | 0.0002 | |
| SRP219564 | SLC35B2 | 347734 | RNAseq | 1.0263 | 0.0075 | |
| TCGA | SLC35B2 | 347734 | RNAseq | 0.0285 | 0.6197 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by SLC35B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC35B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC35B2 | 347734 | 7 | 1 | 22 | |
| GSE20123 | SLC35B2 | 347734 | 7 | 1 | 22 | |
| GSE43470 | SLC35B2 | 347734 | 6 | 0 | 37 | |
| GSE46452 | SLC35B2 | 347734 | 3 | 9 | 47 | |
| GSE47630 | SLC35B2 | 347734 | 8 | 4 | 28 | |
| GSE54993 | SLC35B2 | 347734 | 3 | 2 | 65 | |
| GSE54994 | SLC35B2 | 347734 | 8 | 3 | 42 | |
| GSE60625 | SLC35B2 | 347734 | 0 | 2 | 9 | |
| GSE74703 | SLC35B2 | 347734 | 6 | 0 | 30 | |
| GSE74704 | SLC35B2 | 347734 | 3 | 1 | 16 | |
| TCGA | SLC35B2 | 347734 | 21 | 14 | 61 |
Total number of gains: 72; Total number of losses: 37; Total Number of normals: 379.
Somatic mutations of SLC35B2:
Generating mutation plots.
Highly correlated genes for SLC35B2:
Showing top 20/801 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC35B2 | WDR54 | 0.814968 | 3 | 0 | 3 |
| SLC35B2 | HTRA2 | 0.80991 | 3 | 0 | 3 |
| SLC35B2 | MAD2L2 | 0.807665 | 3 | 0 | 3 |
| SLC35B2 | THOC5 | 0.788214 | 3 | 0 | 3 |
| SLC35B2 | SLC39A7 | 0.78316 | 3 | 0 | 3 |
| SLC35B2 | ABCF1 | 0.77931 | 3 | 0 | 3 |
| SLC35B2 | AATF | 0.778245 | 3 | 0 | 3 |
| SLC35B2 | POLA2 | 0.775926 | 3 | 0 | 3 |
| SLC35B2 | RCN1 | 0.773103 | 3 | 0 | 3 |
| SLC35B2 | SMYD5 | 0.76947 | 3 | 0 | 3 |
| SLC35B2 | SLC25A32 | 0.768052 | 3 | 0 | 3 |
| SLC35B2 | ADSL | 0.768041 | 3 | 0 | 3 |
| SLC35B2 | ATIC | 0.763791 | 3 | 0 | 3 |
| SLC35B2 | RAB15 | 0.763011 | 3 | 0 | 3 |
| SLC35B2 | CNPY2 | 0.762977 | 3 | 0 | 3 |
| SLC35B2 | TMEM97 | 0.762399 | 3 | 0 | 3 |
| SLC35B2 | THOC6 | 0.762349 | 3 | 0 | 3 |
| SLC35B2 | ACLY | 0.761062 | 3 | 0 | 3 |
| SLC35B2 | SDF4 | 0.760424 | 3 | 0 | 3 |
| SLC35B2 | PXDN | 0.758153 | 3 | 0 | 3 |
For details and further investigation, click here
