| Full name: transmembrane protein 60 | Alias Symbol: DC32 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 85025 | HGNC ID: HGNC:21754 | Ensembl Gene: ENSG00000135211 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM60:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM60 | 85025 | 223396_at | 0.0749 | 0.9006 | |
| GSE26886 | TMEM60 | 85025 | 223396_at | 0.0898 | 0.6247 | |
| GSE45670 | TMEM60 | 85025 | 223396_at | 0.0867 | 0.6469 | |
| GSE53622 | TMEM60 | 85025 | 27796 | 0.4639 | 0.0000 | |
| GSE53624 | TMEM60 | 85025 | 27796 | 0.4373 | 0.0000 | |
| GSE63941 | TMEM60 | 85025 | 223396_at | -0.0861 | 0.8780 | |
| GSE77861 | TMEM60 | 85025 | 223396_at | 0.3718 | 0.0592 | |
| GSE97050 | TMEM60 | 85025 | A_24_P166661 | 0.4203 | 0.1852 | |
| SRP007169 | TMEM60 | 85025 | RNAseq | 0.3566 | 0.3599 | |
| SRP008496 | TMEM60 | 85025 | RNAseq | 0.4893 | 0.0808 | |
| SRP064894 | TMEM60 | 85025 | RNAseq | 0.4137 | 0.0730 | |
| SRP133303 | TMEM60 | 85025 | RNAseq | 0.3763 | 0.0490 | |
| SRP159526 | TMEM60 | 85025 | RNAseq | 0.1928 | 0.4373 | |
| SRP193095 | TMEM60 | 85025 | RNAseq | 0.0931 | 0.5273 | |
| SRP219564 | TMEM60 | 85025 | RNAseq | 0.2174 | 0.4851 | |
| TCGA | TMEM60 | 85025 | RNAseq | 0.2058 | 0.0031 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM60 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM60:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM60 | 85025 | 14 | 1 | 15 | |
| GSE20123 | TMEM60 | 85025 | 13 | 1 | 16 | |
| GSE43470 | TMEM60 | 85025 | 4 | 1 | 38 | |
| GSE46452 | TMEM60 | 85025 | 11 | 0 | 48 | |
| GSE47630 | TMEM60 | 85025 | 7 | 3 | 30 | |
| GSE54993 | TMEM60 | 85025 | 1 | 7 | 62 | |
| GSE54994 | TMEM60 | 85025 | 15 | 3 | 35 | |
| GSE60625 | TMEM60 | 85025 | 0 | 0 | 11 | |
| GSE74703 | TMEM60 | 85025 | 3 | 1 | 32 | |
| GSE74704 | TMEM60 | 85025 | 8 | 1 | 11 | |
| TCGA | TMEM60 | 85025 | 44 | 6 | 46 |
Total number of gains: 120; Total number of losses: 24; Total Number of normals: 344.
Somatic mutations of TMEM60:
Generating mutation plots.
Highly correlated genes for TMEM60:
Showing top 20/659 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM60 | SLC38A10 | 0.817095 | 3 | 0 | 3 |
| TMEM60 | SMAD3 | 0.805889 | 3 | 0 | 3 |
| TMEM60 | DUSP18 | 0.798736 | 3 | 0 | 3 |
| TMEM60 | AFAP1L2 | 0.79626 | 3 | 0 | 3 |
| TMEM60 | ADAM9 | 0.791466 | 3 | 0 | 3 |
| TMEM60 | FAM169A | 0.784099 | 3 | 0 | 3 |
| TMEM60 | MTFMT | 0.782634 | 3 | 0 | 3 |
| TMEM60 | BNIP2 | 0.776075 | 3 | 0 | 3 |
| TMEM60 | CELSR2 | 0.770338 | 3 | 0 | 3 |
| TMEM60 | CARD10 | 0.763487 | 3 | 0 | 3 |
| TMEM60 | UXS1 | 0.759986 | 4 | 0 | 4 |
| TMEM60 | PDE8A | 0.756352 | 3 | 0 | 3 |
| TMEM60 | PAK1 | 0.753279 | 3 | 0 | 3 |
| TMEM60 | YLPM1 | 0.752811 | 4 | 0 | 4 |
| TMEM60 | VANGL1 | 0.751534 | 3 | 0 | 3 |
| TMEM60 | ABCB6 | 0.742172 | 3 | 0 | 3 |
| TMEM60 | SLC7A6OS | 0.742093 | 3 | 0 | 3 |
| TMEM60 | MFN1 | 0.739124 | 3 | 0 | 3 |
| TMEM60 | DHX33 | 0.738047 | 4 | 0 | 3 |
| TMEM60 | ATM | 0.734985 | 3 | 0 | 3 |
For details and further investigation, click here
