C9orf64

 

Full name: chromosome 9 open reading frame 64 Alias Symbol: MGC10999
Type: protein-coding gene Cytoband: 9q21.32
Entrez ID: 84267 HGNC ID: HGNC:28144 Ensembl Gene: ENSG00000165118 OMIM ID: 611342
Drug and gene relationship at DGIdb

 

Expression of C9orf64:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C9orf64 84267 223697_x_at 0.1990 0.8084
GSE26886 C9orf64 84267 223697_x_at 0.3689 0.0940
GSE45670 C9orf64 84267 223697_x_at 0.2560 0.0536
GSE53622 C9orf64 84267 89435 0.2532 0.0098
GSE53624 C9orf64 84267 89435 0.4574 0.0000
GSE63941 C9orf64 84267 223697_x_at -0.3761 0.1187
GSE77861 C9orf64 84267 223697_x_at 0.6117 0.1340
GSE97050 C9orf64 84267 A_23_P60339 0.2754 0.4389
SRP007169 C9orf64 84267 RNAseq 1.2423 0.0126
SRP008496 C9orf64 84267 RNAseq 1.4706 0.0009
SRP064894 C9orf64 84267 RNAseq 0.6304 0.0002
SRP133303 C9orf64 84267 RNAseq 0.3002 0.0123
SRP159526 C9orf64 84267 RNAseq 0.3097 0.5024
SRP193095 C9orf64 84267 RNAseq -0.1243 0.3724
SRP219564 C9orf64 84267 RNAseq -0.1716 0.5720
TCGA C9orf64 84267 RNAseq -0.0853 0.2647

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by C9orf64 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C9orf64:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C9orf64 84267 5 10 15
GSE20123 C9orf64 84267 5 10 15
GSE43470 C9orf64 84267 6 3 34
GSE46452 C9orf64 84267 6 14 39
GSE47630 C9orf64 84267 1 18 21
GSE54993 C9orf64 84267 4 2 64
GSE54994 C9orf64 84267 6 12 35
GSE60625 C9orf64 84267 0 0 11
GSE74703 C9orf64 84267 5 3 28
GSE74704 C9orf64 84267 3 7 10
TCGA C9orf64 84267 20 28 48

Total number of gains: 61; Total number of losses: 107; Total Number of normals: 320.  


 

Somatic mutations of C9orf64:

 

Generating mutation plots.

 

Highly correlated genes for C9orf64:

 

Showing top 20/309 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C9orf64ALMS10.92166404
C9orf64SLC22A30.86907505
C9orf64CMBL0.867966505
C9orf64NAA150.855862303
C9orf64UACA0.847506404
C9orf64UFM10.84537303
C9orf64FUT8-AS10.844323404
C9orf64DBT0.841478505
C9orf64CHD70.841011303
C9orf64ZNF6110.833809505
C9orf64FAM161B0.825628606
C9orf64ANKRD10-IT10.82506404
C9orf64MZT2B0.821159706
C9orf64HAUS20.818777706
C9orf64ZC3H7B0.816713504
C9orf64GTF2H30.81531605
C9orf64SLC25A160.787019605
C9orf64DLGAP40.785304706
C9orf64LCAT0.784251303
C9orf64WDR750.772056303

For details and further investigation, click here