| Full name: mitochondrial ribosomal protein S26 | Alias Symbol: MRP-S13|MRP-S26|RPMS13|dJ534B8.3 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 64949 | HGNC ID: HGNC:14045 | Ensembl Gene: ENSG00000125901 | OMIM ID: 611988 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS26 | 64949 | 225196_s_at | 0.5239 | 0.0840 | |
| GSE26886 | MRPS26 | 64949 | 225196_s_at | 1.1719 | 0.0001 | |
| GSE45670 | MRPS26 | 64949 | 225196_s_at | 0.3439 | 0.0599 | |
| GSE53622 | MRPS26 | 64949 | 61197 | 0.4321 | 0.0000 | |
| GSE53624 | MRPS26 | 64949 | 61197 | 0.4525 | 0.0000 | |
| GSE63941 | MRPS26 | 64949 | 225196_s_at | 0.0948 | 0.8338 | |
| GSE77861 | MRPS26 | 64949 | 225196_s_at | 0.3950 | 0.0401 | |
| GSE97050 | MRPS26 | 64949 | A_23_P252536 | 0.1845 | 0.6655 | |
| SRP007169 | MRPS26 | 64949 | RNAseq | -0.4384 | 0.2986 | |
| SRP008496 | MRPS26 | 64949 | RNAseq | 0.3331 | 0.2629 | |
| SRP064894 | MRPS26 | 64949 | RNAseq | 0.6801 | 0.0407 | |
| SRP133303 | MRPS26 | 64949 | RNAseq | 0.3394 | 0.0079 | |
| SRP159526 | MRPS26 | 64949 | RNAseq | 0.8285 | 0.0003 | |
| SRP193095 | MRPS26 | 64949 | RNAseq | 0.2335 | 0.0782 | |
| SRP219564 | MRPS26 | 64949 | RNAseq | 0.5553 | 0.2982 | |
| TCGA | MRPS26 | 64949 | RNAseq | 0.1128 | 0.0849 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPS26 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS26 | 64949 | 12 | 3 | 15 | |
| GSE20123 | MRPS26 | 64949 | 13 | 3 | 14 | |
| GSE43470 | MRPS26 | 64949 | 10 | 1 | 32 | |
| GSE46452 | MRPS26 | 64949 | 26 | 1 | 32 | |
| GSE47630 | MRPS26 | 64949 | 18 | 4 | 18 | |
| GSE54993 | MRPS26 | 64949 | 2 | 14 | 54 | |
| GSE54994 | MRPS26 | 64949 | 24 | 2 | 27 | |
| GSE60625 | MRPS26 | 64949 | 0 | 0 | 11 | |
| GSE74703 | MRPS26 | 64949 | 9 | 1 | 26 | |
| GSE74704 | MRPS26 | 64949 | 8 | 1 | 11 | |
| TCGA | MRPS26 | 64949 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of MRPS26:
Generating mutation plots.
Highly correlated genes for MRPS26:
Showing top 20/1454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS26 | TUBA1B | 0.8129 | 3 | 0 | 3 |
| MRPS26 | MARK1 | 0.800317 | 3 | 0 | 3 |
| MRPS26 | SLC38A10 | 0.789339 | 3 | 0 | 3 |
| MRPS26 | IPO5 | 0.784906 | 3 | 0 | 3 |
| MRPS26 | NUCKS1 | 0.783335 | 3 | 0 | 3 |
| MRPS26 | NAP1L1 | 0.783293 | 3 | 0 | 3 |
| MRPS26 | GGPS1 | 0.778818 | 3 | 0 | 3 |
| MRPS26 | WDR81 | 0.777728 | 3 | 0 | 3 |
| MRPS26 | LRRK1 | 0.775287 | 3 | 0 | 3 |
| MRPS26 | NXT1 | 0.766392 | 8 | 0 | 8 |
| MRPS26 | MCMBP | 0.762708 | 3 | 0 | 3 |
| MRPS26 | ZCCHC17 | 0.75888 | 3 | 0 | 3 |
| MRPS26 | FXR1 | 0.757995 | 3 | 0 | 3 |
| MRPS26 | MCM3AP | 0.757777 | 3 | 0 | 3 |
| MRPS26 | PPP1R10 | 0.757548 | 3 | 0 | 3 |
| MRPS26 | PSMD4 | 0.751689 | 4 | 0 | 4 |
| MRPS26 | BMP2 | 0.751485 | 3 | 0 | 3 |
| MRPS26 | CHCHD6 | 0.749059 | 5 | 0 | 5 |
| MRPS26 | VPS13C | 0.74759 | 3 | 0 | 3 |
| MRPS26 | CLIP2 | 0.745583 | 4 | 0 | 4 |
For details and further investigation, click here
