| Full name: zinc finger and BTB domain containing 11 | Alias Symbol: ZNF-U69274|ZNF913 | ||
| Type: protein-coding gene | Cytoband: 3q12.3 | ||
| Entrez ID: 27107 | HGNC ID: HGNC:16740 | Ensembl Gene: ENSG00000066422 | OMIM ID: 618181 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZBTB11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB11 | 27107 | 204847_at | 0.5717 | 0.2594 | |
| GSE20347 | ZBTB11 | 27107 | 204847_at | 0.2848 | 0.0382 | |
| GSE23400 | ZBTB11 | 27107 | 204847_at | 0.5438 | 0.0000 | |
| GSE26886 | ZBTB11 | 27107 | 204847_at | 0.3091 | 0.2302 | |
| GSE29001 | ZBTB11 | 27107 | 204847_at | 0.3353 | 0.2877 | |
| GSE38129 | ZBTB11 | 27107 | 204847_at | 0.2413 | 0.0278 | |
| GSE45670 | ZBTB11 | 27107 | 204847_at | 0.3408 | 0.0065 | |
| GSE53622 | ZBTB11 | 27107 | 143852 | 0.0836 | 0.3110 | |
| GSE53624 | ZBTB11 | 27107 | 143852 | 0.1134 | 0.2897 | |
| GSE63941 | ZBTB11 | 27107 | 204847_at | 0.2346 | 0.6216 | |
| GSE77861 | ZBTB11 | 27107 | 204847_at | 0.0857 | 0.7990 | |
| GSE97050 | ZBTB11 | 27107 | A_23_P109774 | 0.2120 | 0.2935 | |
| SRP007169 | ZBTB11 | 27107 | RNAseq | -0.0381 | 0.9077 | |
| SRP008496 | ZBTB11 | 27107 | RNAseq | 0.1916 | 0.3706 | |
| SRP064894 | ZBTB11 | 27107 | RNAseq | -0.1870 | 0.4670 | |
| SRP133303 | ZBTB11 | 27107 | RNAseq | 0.2760 | 0.0327 | |
| SRP159526 | ZBTB11 | 27107 | RNAseq | 0.0922 | 0.6316 | |
| SRP193095 | ZBTB11 | 27107 | RNAseq | 0.1651 | 0.0884 | |
| SRP219564 | ZBTB11 | 27107 | RNAseq | 0.0024 | 0.9947 | |
| TCGA | ZBTB11 | 27107 | RNAseq | 0.0776 | 0.1304 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZBTB11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB11 | 27107 | 18 | 1 | 11 | |
| GSE20123 | ZBTB11 | 27107 | 17 | 1 | 12 | |
| GSE43470 | ZBTB11 | 27107 | 17 | 1 | 25 | |
| GSE46452 | ZBTB11 | 27107 | 12 | 6 | 41 | |
| GSE47630 | ZBTB11 | 27107 | 16 | 6 | 18 | |
| GSE54993 | ZBTB11 | 27107 | 2 | 5 | 63 | |
| GSE54994 | ZBTB11 | 27107 | 27 | 5 | 21 | |
| GSE60625 | ZBTB11 | 27107 | 0 | 6 | 5 | |
| GSE74703 | ZBTB11 | 27107 | 14 | 1 | 21 | |
| GSE74704 | ZBTB11 | 27107 | 14 | 1 | 5 | |
| TCGA | ZBTB11 | 27107 | 48 | 9 | 39 |
Total number of gains: 185; Total number of losses: 42; Total Number of normals: 261.
Somatic mutations of ZBTB11:
Generating mutation plots.
Highly correlated genes for ZBTB11:
Showing top 20/873 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB11 | ZNF830 | 0.796318 | 3 | 0 | 3 |
| ZBTB11 | STYX | 0.787008 | 3 | 0 | 3 |
| ZBTB11 | PET117 | 0.772324 | 3 | 0 | 3 |
| ZBTB11 | IFRD2 | 0.770267 | 3 | 0 | 3 |
| ZBTB11 | GPR158 | 0.759674 | 3 | 0 | 3 |
| ZBTB11 | SURF6 | 0.756345 | 3 | 0 | 3 |
| ZBTB11 | WWP1 | 0.746927 | 3 | 0 | 3 |
| ZBTB11 | LEMD2 | 0.74209 | 3 | 0 | 3 |
| ZBTB11 | NFKB1 | 0.736299 | 3 | 0 | 3 |
| ZBTB11 | DCAF13 | 0.734612 | 3 | 0 | 3 |
| ZBTB11 | MMS19 | 0.731192 | 3 | 0 | 3 |
| ZBTB11 | SLU7 | 0.730502 | 3 | 0 | 3 |
| ZBTB11 | ALKBH6 | 0.730275 | 3 | 0 | 3 |
| ZBTB11 | ZNF628 | 0.729182 | 3 | 0 | 3 |
| ZBTB11 | PITRM1 | 0.727716 | 3 | 0 | 3 |
| ZBTB11 | PAN2 | 0.723726 | 3 | 0 | 3 |
| ZBTB11 | CLK2 | 0.722568 | 3 | 0 | 3 |
| ZBTB11 | BICD2 | 0.716974 | 3 | 0 | 3 |
| ZBTB11 | GYS1 | 0.715786 | 3 | 0 | 3 |
| ZBTB11 | ZNF765 | 0.713939 | 3 | 0 | 3 |
For details and further investigation, click here
