OR10A3

 

Full name: olfactory receptor family 10 subfamily A member 3 Alias Symbol: HTPCRX12|HSHTPCRX12
Type: protein-coding gene Cytoband: 11p15.4
Entrez ID: 26496 HGNC ID: HGNC:8162 Ensembl Gene: ENSG00000170683 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR10A3 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR10A3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OR10A3 26496 1567251_at -0.0154 0.9676
GSE26886 OR10A3 26496 1567250_at -0.0630 0.5382
GSE45670 OR10A3 26496 1567251_at 0.1174 0.2453
GSE53622 OR10A3 26496 93440 0.0036 0.9743
GSE53624 OR10A3 26496 93440 0.2427 0.0001
GSE63941 OR10A3 26496 1567250_at 0.1516 0.2790
GSE77861 OR10A3 26496 1567250_at -0.1683 0.1230
TCGA OR10A3 26496 RNAseq 0.3080 0.8285

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OR10A3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of OR10A3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR10A3 26496 0 11 19
GSE20123 OR10A3 26496 0 11 19
GSE43470 OR10A3 26496 1 7 35
GSE46452 OR10A3 26496 7 5 47
GSE47630 OR10A3 26496 2 12 26
GSE54993 OR10A3 26496 3 1 66
GSE54994 OR10A3 26496 2 12 39
GSE60625 OR10A3 26496 0 0 11
GSE74703 OR10A3 26496 1 5 30
GSE74704 OR10A3 26496 0 9 11
TCGA OR10A3 26496 9 36 51

Total number of gains: 25; Total number of losses: 109; Total Number of normals: 354.  


 

Somatic mutations of OR10A3:

 

Generating mutation plots.

 

Highly correlated genes for OR10A3:

 

Showing top 20/75 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR10A3ASB160.705281303
OR10A3AMHR20.681622404
OR10A3CAV30.661956303
OR10A3ATP2B30.637541303
OR10A3FRMPD40.634304303
OR10A3DPYSL50.632793303
OR10A3HORMAD20.632781303
OR10A3ZNF8430.630974303
OR10A3TBATA0.625668404
OR10A3CAMK2B0.620398403
OR10A3OR1F10.615069303
OR10A3C1orf1670.614397404
OR10A3MESP10.609631403
OR10A3LINC002800.607149303
OR10A3LINC003150.603716303
OR10A3HOXB-AS30.60238403
OR10A3ASXL30.601379303
OR10A3PRR290.60079404
OR10A3SDCBP2-AS10.599692303
OR10A3ALDOB0.59381303

For details and further investigation, click here