| Full name: ATPase plasma membrane Ca2+ transporting 3 | Alias Symbol: PMCA3|CFAP39 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 492 | HGNC ID: HGNC:816 | Ensembl Gene: ENSG00000067842 | OMIM ID: 300014 |
| Drug and gene relationship at DGIdb | |||
ATP2B3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway | |
| hsa04022 | cGMP-PKG signaling pathway | |
| hsa04024 | cAMP signaling pathway | |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
Expression of ATP2B3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP2B3 | 492 | 207026_s_at | -0.0254 | 0.9485 | |
| GSE20347 | ATP2B3 | 492 | 207026_s_at | -0.0946 | 0.2210 | |
| GSE23400 | ATP2B3 | 492 | 207026_s_at | -0.1781 | 0.0001 | |
| GSE26886 | ATP2B3 | 492 | 207026_s_at | -0.0314 | 0.8152 | |
| GSE29001 | ATP2B3 | 492 | 207026_s_at | -0.2086 | 0.0836 | |
| GSE38129 | ATP2B3 | 492 | 207026_s_at | -0.1218 | 0.0882 | |
| GSE45670 | ATP2B3 | 492 | 207026_s_at | -0.1192 | 0.1827 | |
| GSE53622 | ATP2B3 | 492 | 9469 | -0.7098 | 0.0000 | |
| GSE53624 | ATP2B3 | 492 | 9469 | -1.4573 | 0.0000 | |
| GSE63941 | ATP2B3 | 492 | 207026_s_at | 0.4233 | 0.0304 | |
| GSE77861 | ATP2B3 | 492 | 215911_x_at | -0.0781 | 0.4881 | |
| GSE97050 | ATP2B3 | 492 | A_23_P337642 | 0.0258 | 0.9335 | |
| TCGA | ATP2B3 | 492 | RNAseq | -2.2291 | 0.0171 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ATP2B3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP2B3:
No record found for this gene.
Somatic mutations of ATP2B3:
Generating mutation plots.
Highly correlated genes for ATP2B3:
Showing top 20/855 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP2B3 | RNF222 | 0.855847 | 3 | 0 | 3 |
| ATP2B3 | NOTO | 0.838876 | 3 | 0 | 3 |
| ATP2B3 | KRTAP5-5 | 0.832841 | 3 | 0 | 3 |
| ATP2B3 | CLEC18C | 0.825544 | 3 | 0 | 3 |
| ATP2B3 | BARHL2 | 0.818052 | 3 | 0 | 3 |
| ATP2B3 | TSSK3 | 0.803707 | 3 | 0 | 3 |
| ATP2B3 | KRTAP5-4 | 0.796982 | 3 | 0 | 3 |
| ATP2B3 | GPR62 | 0.755573 | 5 | 0 | 4 |
| ATP2B3 | PHLDB3 | 0.752624 | 3 | 0 | 3 |
| ATP2B3 | MGAT5B | 0.748411 | 3 | 0 | 3 |
| ATP2B3 | TEKT2 | 0.746641 | 5 | 0 | 5 |
| ATP2B3 | MAGEA8 | 0.735411 | 3 | 0 | 3 |
| ATP2B3 | LIM2 | 0.730741 | 3 | 0 | 3 |
| ATP2B3 | TIGD5 | 0.722967 | 4 | 0 | 3 |
| ATP2B3 | ASB10 | 0.720181 | 3 | 0 | 3 |
| ATP2B3 | KRTAP5-11 | 0.720152 | 3 | 0 | 3 |
| ATP2B3 | AQP10 | 0.718824 | 3 | 0 | 3 |
| ATP2B3 | STAC2 | 0.717692 | 3 | 0 | 3 |
| ATP2B3 | C11orf94 | 0.717288 | 3 | 0 | 3 |
| ATP2B3 | MEI1 | 0.71667 | 3 | 0 | 3 |
For details and further investigation, click here
