| Full name: caveolin 3 | Alias Symbol: VIP-21|LGMD1C|VIP21|LQT9 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 859 | HGNC ID: HGNC:1529 | Ensembl Gene: ENSG00000182533 | OMIM ID: 601253 |
| Drug and gene relationship at DGIdb | |||
CAV3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04510 | Focal adhesion | |
| hsa05205 | Proteoglycans in cancer |
Expression of CAV3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAV3 | 859 | 208204_s_at | -0.0160 | 0.9676 | |
| GSE20347 | CAV3 | 859 | 208204_s_at | -0.1355 | 0.0787 | |
| GSE23400 | CAV3 | 859 | 208204_s_at | -0.1686 | 0.0000 | |
| GSE26886 | CAV3 | 859 | 208204_s_at | -0.0856 | 0.5360 | |
| GSE29001 | CAV3 | 859 | 208204_s_at | -0.3292 | 0.0550 | |
| GSE38129 | CAV3 | 859 | 208204_s_at | -0.2169 | 0.0032 | |
| GSE45670 | CAV3 | 859 | 208204_s_at | 0.0416 | 0.6510 | |
| GSE53622 | CAV3 | 859 | 95911 | 0.6671 | 0.0004 | |
| GSE53624 | CAV3 | 859 | 95911 | 1.0516 | 0.0000 | |
| GSE63941 | CAV3 | 859 | 208204_s_at | 0.2006 | 0.1650 | |
| GSE77861 | CAV3 | 859 | 208204_s_at | -0.0789 | 0.3690 | |
| GSE97050 | CAV3 | 859 | A_24_P251599 | -0.0426 | 0.8353 | |
| TCGA | CAV3 | 859 | RNAseq | -0.9375 | 0.4188 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CAV3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAV3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAV3 | 859 | 1 | 18 | 11 | |
| GSE20123 | CAV3 | 859 | 1 | 18 | 11 | |
| GSE43470 | CAV3 | 859 | 0 | 20 | 23 | |
| GSE46452 | CAV3 | 859 | 2 | 17 | 40 | |
| GSE47630 | CAV3 | 859 | 1 | 23 | 16 | |
| GSE54993 | CAV3 | 859 | 6 | 1 | 63 | |
| GSE54994 | CAV3 | 859 | 3 | 31 | 19 | |
| GSE60625 | CAV3 | 859 | 5 | 0 | 6 | |
| GSE74703 | CAV3 | 859 | 0 | 17 | 19 | |
| GSE74704 | CAV3 | 859 | 1 | 11 | 8 | |
| TCGA | CAV3 | 859 | 5 | 65 | 26 |
Total number of gains: 25; Total number of losses: 221; Total Number of normals: 242.
Somatic mutations of CAV3:
Generating mutation plots.
Highly correlated genes for CAV3:
Showing top 20/883 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAV3 | UBE2D4 | 0.765287 | 3 | 0 | 3 |
| CAV3 | CLEC14A | 0.739809 | 3 | 0 | 3 |
| CAV3 | STAC | 0.734904 | 4 | 0 | 4 |
| CAV3 | C10orf82 | 0.722364 | 3 | 0 | 3 |
| CAV3 | TSPAN7 | 0.722249 | 3 | 0 | 3 |
| CAV3 | CYGB | 0.718602 | 3 | 0 | 3 |
| CAV3 | AAAS | 0.7123 | 3 | 0 | 3 |
| CAV3 | MUC6 | 0.708154 | 3 | 0 | 3 |
| CAV3 | HOXB3 | 0.707598 | 3 | 0 | 3 |
| CAV3 | MCC | 0.705544 | 3 | 0 | 3 |
| CAV3 | ADPRH | 0.69527 | 8 | 0 | 8 |
| CAV3 | ASIC1 | 0.69374 | 3 | 0 | 3 |
| CAV3 | MTAP | 0.690574 | 5 | 0 | 4 |
| CAV3 | RABEP2 | 0.689935 | 5 | 0 | 5 |
| CAV3 | MR1 | 0.68891 | 3 | 0 | 3 |
| CAV3 | SLC28A2 | 0.688875 | 5 | 0 | 5 |
| CAV3 | COPZ2 | 0.688325 | 4 | 0 | 4 |
| CAV3 | PTGFRN | 0.684558 | 4 | 0 | 4 |
| CAV3 | DENND5B | 0.680882 | 3 | 0 | 3 |
| CAV3 | IL18BP | 0.680521 | 6 | 0 | 5 |
For details and further investigation, click here
