| Full name: mesoderm posterior bHLH transcription factor 1 | Alias Symbol: MGC10676|bHLHc5 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 55897 | HGNC ID: HGNC:29658 | Ensembl Gene: ENSG00000166823 | OMIM ID: 608689 |
| Drug and gene relationship at DGIdb | |||
Expression of MESP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MESP1 | 55897 | 229195_at | 0.0264 | 0.9385 | |
| GSE26886 | MESP1 | 55897 | 229195_at | -0.1072 | 0.4159 | |
| GSE45670 | MESP1 | 55897 | 229195_at | 0.0136 | 0.8924 | |
| GSE53622 | MESP1 | 55897 | 30746 | 0.1454 | 0.5314 | |
| GSE53624 | MESP1 | 55897 | 30746 | 0.0828 | 0.6974 | |
| GSE63941 | MESP1 | 55897 | 229195_at | 0.3640 | 0.0297 | |
| GSE77861 | MESP1 | 55897 | 229195_at | -0.0841 | 0.4104 | |
| SRP159526 | MESP1 | 55897 | RNAseq | 1.6025 | 0.0131 | |
| SRP219564 | MESP1 | 55897 | RNAseq | 0.0392 | 0.9638 | |
| TCGA | MESP1 | 55897 | RNAseq | 0.3307 | 0.4650 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MESP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MESP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MESP1 | 55897 | 8 | 3 | 19 | |
| GSE20123 | MESP1 | 55897 | 8 | 3 | 19 | |
| GSE43470 | MESP1 | 55897 | 5 | 4 | 34 | |
| GSE46452 | MESP1 | 55897 | 3 | 7 | 49 | |
| GSE47630 | MESP1 | 55897 | 8 | 11 | 21 | |
| GSE54993 | MESP1 | 55897 | 4 | 6 | 60 | |
| GSE54994 | MESP1 | 55897 | 7 | 6 | 40 | |
| GSE60625 | MESP1 | 55897 | 4 | 0 | 7 | |
| GSE74703 | MESP1 | 55897 | 4 | 3 | 29 | |
| GSE74704 | MESP1 | 55897 | 4 | 2 | 14 | |
| TCGA | MESP1 | 55897 | 17 | 12 | 67 |
Total number of gains: 72; Total number of losses: 57; Total Number of normals: 359.
Somatic mutations of MESP1:
Generating mutation plots.
Highly correlated genes for MESP1:
Showing top 20/44 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MESP1 | NXPH3 | 0.66624 | 3 | 0 | 3 |
| MESP1 | AQP6 | 0.656662 | 3 | 0 | 3 |
| MESP1 | GAB4 | 0.649548 | 3 | 0 | 3 |
| MESP1 | PYY | 0.641549 | 3 | 0 | 3 |
| MESP1 | ZSCAN10 | 0.639006 | 3 | 0 | 3 |
| MESP1 | MTNR1A | 0.63501 | 3 | 0 | 3 |
| MESP1 | MORF4L2-AS1 | 0.62753 | 3 | 0 | 3 |
| MESP1 | GRIK1-AS2 | 0.614339 | 4 | 0 | 3 |
| MESP1 | C3orf62 | 0.611428 | 3 | 0 | 3 |
| MESP1 | PRKACG | 0.609809 | 3 | 0 | 3 |
| MESP1 | GPR75 | 0.609744 | 3 | 0 | 3 |
| MESP1 | OR10A3 | 0.609631 | 4 | 0 | 3 |
| MESP1 | DLX2 | 0.603837 | 4 | 0 | 3 |
| MESP1 | LEMD1-AS1 | 0.603733 | 3 | 0 | 3 |
| MESP1 | RETNLB | 0.594313 | 4 | 0 | 3 |
| MESP1 | CACNA1G | 0.590434 | 4 | 0 | 4 |
| MESP1 | CYLC1 | 0.590314 | 3 | 0 | 3 |
| MESP1 | BRSK2 | 0.580283 | 4 | 0 | 3 |
| MESP1 | LGI4 | 0.580174 | 3 | 0 | 3 |
| MESP1 | KRBOX1-AS1 | 0.577663 | 3 | 0 | 3 |
For details and further investigation, click here
