| Full name: aldolase, fructose-bisphosphate B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q31.1 | ||
| Entrez ID: 229 | HGNC ID: HGNC:417 | Ensembl Gene: ENSG00000136872 | OMIM ID: 612724 |
| Drug and gene relationship at DGIdb | |||
Expression of ALDOB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDOB | 229 | 216600_x_at | 0.0862 | 0.6577 | |
| GSE20347 | ALDOB | 229 | 216600_x_at | 0.0971 | 0.4415 | |
| GSE23400 | ALDOB | 229 | 216600_x_at | -0.1133 | 0.0025 | |
| GSE26886 | ALDOB | 229 | 216600_x_at | 0.1125 | 0.3858 | |
| GSE29001 | ALDOB | 229 | 216600_x_at | -0.0049 | 0.9718 | |
| GSE38129 | ALDOB | 229 | 216600_x_at | -0.0891 | 0.3615 | |
| GSE45670 | ALDOB | 229 | 216600_x_at | 0.0538 | 0.5350 | |
| GSE53622 | ALDOB | 229 | 64436 | -0.5036 | 0.0572 | |
| GSE53624 | ALDOB | 229 | 64436 | -0.4530 | 0.0241 | |
| GSE63941 | ALDOB | 229 | 216600_x_at | 0.2464 | 0.1877 | |
| GSE77861 | ALDOB | 229 | 216600_x_at | -0.0243 | 0.8653 | |
| TCGA | ALDOB | 229 | RNAseq | -4.5225 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ALDOB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDOB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDOB | 229 | 4 | 10 | 16 | |
| GSE20123 | ALDOB | 229 | 5 | 9 | 16 | |
| GSE43470 | ALDOB | 229 | 6 | 3 | 34 | |
| GSE46452 | ALDOB | 229 | 6 | 13 | 40 | |
| GSE47630 | ALDOB | 229 | 1 | 17 | 22 | |
| GSE54993 | ALDOB | 229 | 3 | 3 | 64 | |
| GSE54994 | ALDOB | 229 | 9 | 11 | 33 | |
| GSE60625 | ALDOB | 229 | 0 | 0 | 11 | |
| GSE74703 | ALDOB | 229 | 5 | 3 | 28 | |
| GSE74704 | ALDOB | 229 | 2 | 6 | 12 | |
| TCGA | ALDOB | 229 | 28 | 21 | 47 |
Total number of gains: 69; Total number of losses: 96; Total Number of normals: 323.
Somatic mutations of ALDOB:
Generating mutation plots.
Highly correlated genes for ALDOB:
Showing top 20/881 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDOB | LBP | 0.709479 | 3 | 0 | 3 |
| ALDOB | RECK | 0.684431 | 3 | 0 | 3 |
| ALDOB | RCVRN | 0.68354 | 5 | 0 | 5 |
| ALDOB | NAA11 | 0.676703 | 3 | 0 | 3 |
| ALDOB | ADAM7 | 0.675734 | 4 | 0 | 4 |
| ALDOB | SLC9A7 | 0.675087 | 3 | 0 | 3 |
| ALDOB | DEFA6 | 0.674582 | 5 | 0 | 5 |
| ALDOB | CGA | 0.672522 | 5 | 0 | 5 |
| ALDOB | GRM6 | 0.671385 | 4 | 0 | 4 |
| ALDOB | PRODH2 | 0.668688 | 7 | 0 | 6 |
| ALDOB | OBSL1 | 0.667684 | 3 | 0 | 3 |
| ALDOB | IFNA21 | 0.667014 | 4 | 0 | 4 |
| ALDOB | HRG | 0.6652 | 4 | 0 | 3 |
| ALDOB | PRAMEF12 | 0.66465 | 6 | 0 | 6 |
| ALDOB | SIGLEC6 | 0.66456 | 4 | 0 | 4 |
| ALDOB | IL1RAPL2 | 0.663881 | 5 | 0 | 5 |
| ALDOB | TFDP3 | 0.662887 | 4 | 0 | 4 |
| ALDOB | JAK3 | 0.662293 | 6 | 0 | 6 |
| ALDOB | FAM76A | 0.660667 | 4 | 0 | 4 |
| ALDOB | TMPRSS5 | 0.660384 | 6 | 0 | 5 |
For details and further investigation, click here
