GCM2

 

Full name: glial cells missing transcription factor 2 Alias Symbol: hGCMb
Type: protein-coding gene Cytoband: 6p24.2
Entrez ID: 9247 HGNC ID: HGNC:4198 Ensembl Gene: ENSG00000124827 OMIM ID: 603716
Drug and gene relationship at DGIdb

 

Expression of GCM2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GCM2 9247 220799_at 0.0800 0.8109
GSE20347 GCM2 9247 220799_at -0.0252 0.5767
GSE23400 GCM2 9247 220799_at -0.0422 0.0085
GSE26886 GCM2 9247 220799_at 0.0643 0.4123
GSE29001 GCM2 9247 220799_at -0.1051 0.3709
GSE38129 GCM2 9247 220799_at -0.0295 0.4214
GSE45670 GCM2 9247 220799_at -0.0130 0.8497
GSE53622 GCM2 9247 35065 0.3175 0.0001
GSE53624 GCM2 9247 35065 0.0028 0.9857
GSE63941 GCM2 9247 220799_at 0.0884 0.4215
GSE77861 GCM2 9247 220799_at -0.0046 0.9545
GSE97050 GCM2 9247 A_23_P59285 -0.0676 0.7732
TCGA GCM2 9247 RNAseq 0.4607 0.7171

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GCM2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GCM2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GCM2 9247 4 7 19
GSE20123 GCM2 9247 4 7 19
GSE43470 GCM2 9247 8 2 33
GSE46452 GCM2 9247 1 10 48
GSE47630 GCM2 9247 7 8 25
GSE54993 GCM2 9247 1 1 68
GSE54994 GCM2 9247 10 3 40
GSE60625 GCM2 9247 0 1 10
GSE74703 GCM2 9247 7 2 27
GSE74704 GCM2 9247 2 3 15
TCGA GCM2 9247 15 28 53

Total number of gains: 59; Total number of losses: 72; Total Number of normals: 357.  


 

Somatic mutations of GCM2:

 

Generating mutation plots.

 

Highly correlated genes for GCM2:

 

Showing top 20/443 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GCM2SLC39A50.886072303
GCM2SUN50.850071303
GCM2DCDC10.840523303
GCM2OR2A50.828942303
GCM2STRC0.82892303
GCM2PLA2G2C0.828242303
GCM2IL1F100.813855303
GCM2ZNF8430.810167303
GCM2OR2T270.804898303
GCM2OR2T10.804512303
GCM2TBX40.801947303
GCM2NKX6-30.796858303
GCM2BTNL20.781771504
GCM2SYCN0.780028303
GCM2PABPN1L0.778638303
GCM2ST8SIA10.776746303
GCM2SLC5A40.770048303
GCM2BBC30.765313303
GCM2PNPLA70.763225404
GCM2YY20.763037303

For details and further investigation, click here