| Full name: protein kinase C and casein kinase substrate in neurons 2 | Alias Symbol: SDPII | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 11252 | HGNC ID: HGNC:8571 | Ensembl Gene: ENSG00000100266 | OMIM ID: 604960 |
| Drug and gene relationship at DGIdb | |||
Expression of PACSIN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PACSIN2 | 11252 | 201651_s_at | -0.1953 | 0.7111 | |
| GSE20347 | PACSIN2 | 11252 | 201651_s_at | -0.0199 | 0.9088 | |
| GSE23400 | PACSIN2 | 11252 | 201651_s_at | -0.0247 | 0.7892 | |
| GSE26886 | PACSIN2 | 11252 | 201651_s_at | 0.8898 | 0.0000 | |
| GSE29001 | PACSIN2 | 11252 | 201651_s_at | 0.1587 | 0.6573 | |
| GSE38129 | PACSIN2 | 11252 | 201651_s_at | -0.1787 | 0.4509 | |
| GSE45670 | PACSIN2 | 11252 | 201651_s_at | -0.3181 | 0.0227 | |
| GSE53622 | PACSIN2 | 11252 | 59707 | -0.5946 | 0.0000 | |
| GSE53624 | PACSIN2 | 11252 | 59707 | -1.0943 | 0.0000 | |
| GSE63941 | PACSIN2 | 11252 | 201651_s_at | 0.6587 | 0.2394 | |
| GSE77861 | PACSIN2 | 11252 | 201651_s_at | 0.4897 | 0.0088 | |
| GSE97050 | PACSIN2 | 11252 | A_33_P3314192 | -0.3247 | 0.2063 | |
| SRP007169 | PACSIN2 | 11252 | RNAseq | 0.7251 | 0.1232 | |
| SRP008496 | PACSIN2 | 11252 | RNAseq | 0.9229 | 0.0136 | |
| SRP064894 | PACSIN2 | 11252 | RNAseq | 0.0604 | 0.6675 | |
| SRP133303 | PACSIN2 | 11252 | RNAseq | -0.1801 | 0.2682 | |
| SRP159526 | PACSIN2 | 11252 | RNAseq | -0.0778 | 0.7447 | |
| SRP193095 | PACSIN2 | 11252 | RNAseq | -0.0635 | 0.6259 | |
| SRP219564 | PACSIN2 | 11252 | RNAseq | 0.1551 | 0.7235 | |
| TCGA | PACSIN2 | 11252 | RNAseq | -0.3075 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PACSIN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PACSIN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PACSIN2 | 11252 | 6 | 6 | 18 | |
| GSE20123 | PACSIN2 | 11252 | 6 | 5 | 19 | |
| GSE43470 | PACSIN2 | 11252 | 3 | 6 | 34 | |
| GSE46452 | PACSIN2 | 11252 | 31 | 2 | 26 | |
| GSE47630 | PACSIN2 | 11252 | 9 | 4 | 27 | |
| GSE54993 | PACSIN2 | 11252 | 3 | 6 | 61 | |
| GSE54994 | PACSIN2 | 11252 | 11 | 8 | 34 | |
| GSE60625 | PACSIN2 | 11252 | 5 | 0 | 6 | |
| GSE74703 | PACSIN2 | 11252 | 3 | 4 | 29 | |
| GSE74704 | PACSIN2 | 11252 | 3 | 3 | 14 | |
| TCGA | PACSIN2 | 11252 | 26 | 15 | 55 |
Total number of gains: 106; Total number of losses: 59; Total Number of normals: 323.
Somatic mutations of PACSIN2:
Generating mutation plots.
Highly correlated genes for PACSIN2:
Showing top 20/626 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PACSIN2 | FNIP2 | 0.787632 | 3 | 0 | 3 |
| PACSIN2 | ZCCHC17 | 0.78056 | 3 | 0 | 3 |
| PACSIN2 | LSM10 | 0.780356 | 3 | 0 | 3 |
| PACSIN2 | KLHL13 | 0.777971 | 3 | 0 | 3 |
| PACSIN2 | NUDT16 | 0.777224 | 3 | 0 | 3 |
| PACSIN2 | CEP44 | 0.777107 | 3 | 0 | 3 |
| PACSIN2 | PLEKHA3 | 0.771124 | 3 | 0 | 3 |
| PACSIN2 | WDR81 | 0.767196 | 3 | 0 | 3 |
| PACSIN2 | ERRFI1 | 0.765213 | 3 | 0 | 3 |
| PACSIN2 | ZNF664 | 0.763704 | 3 | 0 | 3 |
| PACSIN2 | SSBP4 | 0.763226 | 3 | 0 | 3 |
| PACSIN2 | CNRIP1 | 0.758975 | 3 | 0 | 3 |
| PACSIN2 | GLYR1 | 0.749185 | 3 | 0 | 3 |
| PACSIN2 | ZNF449 | 0.743045 | 5 | 0 | 5 |
| PACSIN2 | RILPL1 | 0.741606 | 3 | 0 | 3 |
| PACSIN2 | CREB3 | 0.739249 | 4 | 0 | 3 |
| PACSIN2 | TTF1 | 0.737932 | 3 | 0 | 3 |
| PACSIN2 | UBR1 | 0.73553 | 3 | 0 | 3 |
| PACSIN2 | SDHAF2 | 0.734129 | 3 | 0 | 3 |
| PACSIN2 | TMEM204 | 0.729139 | 4 | 0 | 4 |
For details and further investigation, click here
