| Full name: glyoxylate reductase 1 homolog | Alias Symbol: BM045|HIBDL|NP60|N-PAC | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 84656 | HGNC ID: HGNC:24434 | Ensembl Gene: ENSG00000140632 | OMIM ID: 610660 |
| Drug and gene relationship at DGIdb | |||
Expression of GLYR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLYR1 | 84656 | 218506_x_at | -0.0039 | 0.9954 | |
| GSE20347 | GLYR1 | 84656 | 218506_x_at | -0.0860 | 0.3379 | |
| GSE23400 | GLYR1 | 84656 | 218506_x_at | 0.0320 | 0.6231 | |
| GSE26886 | GLYR1 | 84656 | 218506_x_at | -0.7168 | 0.0051 | |
| GSE29001 | GLYR1 | 84656 | 218506_x_at | -0.0624 | 0.8478 | |
| GSE38129 | GLYR1 | 84656 | 218506_x_at | -0.1559 | 0.1095 | |
| GSE45670 | GLYR1 | 84656 | 218506_x_at | 0.1087 | 0.2739 | |
| GSE53622 | GLYR1 | 84656 | 13277 | -0.0661 | 0.3264 | |
| GSE53624 | GLYR1 | 84656 | 13277 | -0.0775 | 0.2214 | |
| GSE63941 | GLYR1 | 84656 | 218506_x_at | -0.1379 | 0.6627 | |
| GSE77861 | GLYR1 | 84656 | 218506_x_at | 0.0427 | 0.8333 | |
| GSE97050 | GLYR1 | 84656 | A_32_P743407 | -0.4280 | 0.2308 | |
| SRP007169 | GLYR1 | 84656 | RNAseq | 0.4405 | 0.3648 | |
| SRP008496 | GLYR1 | 84656 | RNAseq | 0.1067 | 0.7433 | |
| SRP064894 | GLYR1 | 84656 | RNAseq | -0.3031 | 0.0305 | |
| SRP133303 | GLYR1 | 84656 | RNAseq | 0.1548 | 0.2835 | |
| SRP159526 | GLYR1 | 84656 | RNAseq | -0.3434 | 0.0621 | |
| SRP193095 | GLYR1 | 84656 | RNAseq | -0.0743 | 0.3471 | |
| SRP219564 | GLYR1 | 84656 | RNAseq | -0.2194 | 0.5136 | |
| TCGA | GLYR1 | 84656 | RNAseq | -0.1478 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GLYR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLYR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLYR1 | 84656 | 6 | 5 | 19 | |
| GSE20123 | GLYR1 | 84656 | 6 | 4 | 20 | |
| GSE43470 | GLYR1 | 84656 | 4 | 5 | 34 | |
| GSE46452 | GLYR1 | 84656 | 38 | 1 | 20 | |
| GSE47630 | GLYR1 | 84656 | 13 | 6 | 21 | |
| GSE54993 | GLYR1 | 84656 | 3 | 5 | 62 | |
| GSE54994 | GLYR1 | 84656 | 5 | 9 | 39 | |
| GSE60625 | GLYR1 | 84656 | 4 | 0 | 7 | |
| GSE74703 | GLYR1 | 84656 | 4 | 4 | 28 | |
| GSE74704 | GLYR1 | 84656 | 3 | 2 | 15 | |
| TCGA | GLYR1 | 84656 | 19 | 13 | 64 |
Total number of gains: 105; Total number of losses: 54; Total Number of normals: 329.
Somatic mutations of GLYR1:
Generating mutation plots.
Highly correlated genes for GLYR1:
Showing top 20/293 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLYR1 | NDUFA12 | 0.852884 | 3 | 0 | 3 |
| GLYR1 | QRICH1 | 0.829214 | 3 | 0 | 3 |
| GLYR1 | TANC1 | 0.819352 | 3 | 0 | 3 |
| GLYR1 | PHKB | 0.801246 | 3 | 0 | 3 |
| GLYR1 | C5orf51 | 0.795398 | 3 | 0 | 3 |
| GLYR1 | ZNF564 | 0.776489 | 3 | 0 | 3 |
| GLYR1 | PITHD1 | 0.773503 | 3 | 0 | 3 |
| GLYR1 | LUC7L2 | 0.771226 | 4 | 0 | 3 |
| GLYR1 | MYSM1 | 0.766498 | 3 | 0 | 3 |
| GLYR1 | HDHD2 | 0.762488 | 3 | 0 | 3 |
| GLYR1 | ALAS1 | 0.75827 | 3 | 0 | 3 |
| GLYR1 | CRNKL1 | 0.757912 | 3 | 0 | 3 |
| GLYR1 | NAA30 | 0.751638 | 3 | 0 | 3 |
| GLYR1 | PACSIN2 | 0.749185 | 3 | 0 | 3 |
| GLYR1 | RSBN1L | 0.74874 | 3 | 0 | 3 |
| GLYR1 | BTRC | 0.746184 | 3 | 0 | 3 |
| GLYR1 | QTRT1 | 0.745879 | 3 | 0 | 3 |
| GLYR1 | LONRF1 | 0.74546 | 3 | 0 | 3 |
| GLYR1 | MCPH1 | 0.74109 | 3 | 0 | 3 |
| GLYR1 | GLUD1 | 0.738248 | 4 | 0 | 4 |
For details and further investigation, click here
