| Full name: folliculin interacting protein 2 | Alias Symbol: KIAA1450|FNIPL|MAPO1 | ||
| Type: protein-coding gene | Cytoband: 4q32.1 | ||
| Entrez ID: 57600 | HGNC ID: HGNC:29280 | Ensembl Gene: ENSG00000052795 | OMIM ID: 612768 |
| Drug and gene relationship at DGIdb | |||
FNIP2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04150 | mTOR signaling pathway |
Expression of FNIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FNIP2 | 57600 | 225922_at | -0.6042 | 0.3088 | |
| GSE26886 | FNIP2 | 57600 | 225924_at | 0.6473 | 0.0190 | |
| GSE45670 | FNIP2 | 57600 | 225922_at | -0.4281 | 0.0984 | |
| GSE63941 | FNIP2 | 57600 | 225922_at | -1.9277 | 0.0077 | |
| GSE77861 | FNIP2 | 57600 | 225922_at | 0.2492 | 0.6203 | |
| GSE97050 | FNIP2 | 57600 | A_33_P3805090 | -0.1114 | 0.7701 | |
| SRP007169 | FNIP2 | 57600 | RNAseq | 0.8422 | 0.1127 | |
| SRP008496 | FNIP2 | 57600 | RNAseq | 1.0963 | 0.0060 | |
| SRP064894 | FNIP2 | 57600 | RNAseq | 0.1262 | 0.7152 | |
| SRP133303 | FNIP2 | 57600 | RNAseq | 0.2708 | 0.2239 | |
| SRP159526 | FNIP2 | 57600 | RNAseq | -0.3704 | 0.1592 | |
| SRP193095 | FNIP2 | 57600 | RNAseq | -0.0699 | 0.7367 | |
| SRP219564 | FNIP2 | 57600 | RNAseq | -0.2542 | 0.6283 | |
| TCGA | FNIP2 | 57600 | RNAseq | -0.5120 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by FNIP2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FNIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FNIP2 | 57600 | 0 | 13 | 17 | |
| GSE20123 | FNIP2 | 57600 | 0 | 13 | 17 | |
| GSE43470 | FNIP2 | 57600 | 0 | 14 | 29 | |
| GSE46452 | FNIP2 | 57600 | 1 | 36 | 22 | |
| GSE47630 | FNIP2 | 57600 | 0 | 23 | 17 | |
| GSE54993 | FNIP2 | 57600 | 10 | 0 | 60 | |
| GSE54994 | FNIP2 | 57600 | 1 | 12 | 40 | |
| GSE60625 | FNIP2 | 57600 | 0 | 1 | 10 | |
| GSE74703 | FNIP2 | 57600 | 0 | 12 | 24 | |
| GSE74704 | FNIP2 | 57600 | 0 | 6 | 14 | |
| TCGA | FNIP2 | 57600 | 12 | 35 | 49 |
Total number of gains: 24; Total number of losses: 165; Total Number of normals: 299.
Somatic mutations of FNIP2:
Generating mutation plots.
Highly correlated genes for FNIP2:
Showing top 20/615 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FNIP2 | FRY | 0.831228 | 3 | 0 | 3 |
| FNIP2 | EZH1 | 0.816185 | 3 | 0 | 3 |
| FNIP2 | PDGFRA | 0.810783 | 3 | 0 | 3 |
| FNIP2 | JMY | 0.809147 | 3 | 0 | 3 |
| FNIP2 | EPB41L2 | 0.797627 | 3 | 0 | 3 |
| FNIP2 | CORO2B | 0.794884 | 3 | 0 | 3 |
| FNIP2 | ZFAND5 | 0.78893 | 3 | 0 | 3 |
| FNIP2 | PACSIN2 | 0.787632 | 3 | 0 | 3 |
| FNIP2 | PKD2 | 0.785263 | 4 | 0 | 4 |
| FNIP2 | FZD7 | 0.782987 | 3 | 0 | 3 |
| FNIP2 | CDS2 | 0.781284 | 3 | 0 | 3 |
| FNIP2 | IMMP2L | 0.779776 | 3 | 0 | 3 |
| FNIP2 | FAM13B | 0.777877 | 3 | 0 | 3 |
| FNIP2 | THOC2 | 0.776403 | 3 | 0 | 3 |
| FNIP2 | DNALI1 | 0.771492 | 3 | 0 | 3 |
| FNIP2 | DIAPH2 | 0.771273 | 3 | 0 | 3 |
| FNIP2 | PGRMC2 | 0.771119 | 3 | 0 | 3 |
| FNIP2 | AFF3 | 0.770062 | 3 | 0 | 3 |
| FNIP2 | LIMS2 | 0.769992 | 3 | 0 | 3 |
| FNIP2 | MTRF1L | 0.765455 | 3 | 0 | 3 |
For details and further investigation, click here
