| Full name: ERBB receptor feedback inhibitor 1 | Alias Symbol: MIG-6|GENE-33|RALT | ||
| Type: protein-coding gene | Cytoband: 1p36.23 | ||
| Entrez ID: 54206 | HGNC ID: HGNC:18185 | Ensembl Gene: ENSG00000116285 | OMIM ID: 608069 |
| Drug and gene relationship at DGIdb | |||
Expression of ERRFI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERRFI1 | 54206 | 224657_at | -0.6352 | 0.6045 | |
| GSE26886 | ERRFI1 | 54206 | 224657_at | -0.0379 | 0.9242 | |
| GSE45670 | ERRFI1 | 54206 | 224657_at | -0.5398 | 0.1755 | |
| GSE53622 | ERRFI1 | 54206 | 9157 | -0.0444 | 0.8121 | |
| GSE53624 | ERRFI1 | 54206 | 9157 | -0.0193 | 0.8667 | |
| GSE63941 | ERRFI1 | 54206 | 224657_at | -1.5120 | 0.1559 | |
| GSE77861 | ERRFI1 | 54206 | 224657_at | 0.9540 | 0.0458 | |
| GSE97050 | ERRFI1 | 54206 | A_23_P46470 | -0.4635 | 0.4376 | |
| SRP007169 | ERRFI1 | 54206 | RNAseq | 0.5228 | 0.3424 | |
| SRP008496 | ERRFI1 | 54206 | RNAseq | 0.5107 | 0.1227 | |
| SRP064894 | ERRFI1 | 54206 | RNAseq | -0.1794 | 0.5973 | |
| SRP133303 | ERRFI1 | 54206 | RNAseq | 0.6386 | 0.1155 | |
| SRP159526 | ERRFI1 | 54206 | RNAseq | 0.4569 | 0.4775 | |
| SRP193095 | ERRFI1 | 54206 | RNAseq | 0.2492 | 0.2776 | |
| TCGA | ERRFI1 | 54206 | RNAseq | -0.3710 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ERRFI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERRFI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERRFI1 | 54206 | 1 | 5 | 24 | |
| GSE20123 | ERRFI1 | 54206 | 1 | 3 | 26 | |
| GSE43470 | ERRFI1 | 54206 | 6 | 5 | 32 | |
| GSE46452 | ERRFI1 | 54206 | 7 | 1 | 51 | |
| GSE47630 | ERRFI1 | 54206 | 8 | 4 | 28 | |
| GSE54993 | ERRFI1 | 54206 | 3 | 2 | 65 | |
| GSE54994 | ERRFI1 | 54206 | 13 | 3 | 37 | |
| GSE60625 | ERRFI1 | 54206 | 0 | 0 | 11 | |
| GSE74703 | ERRFI1 | 54206 | 5 | 3 | 28 | |
| GSE74704 | ERRFI1 | 54206 | 1 | 0 | 19 | |
| TCGA | ERRFI1 | 54206 | 11 | 23 | 62 |
Total number of gains: 56; Total number of losses: 49; Total Number of normals: 383.
Somatic mutations of ERRFI1:
Generating mutation plots.
Highly correlated genes for ERRFI1:
Showing top 20/316 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERRFI1 | GNB4 | 0.794035 | 3 | 0 | 3 |
| ERRFI1 | KIAA0753 | 0.785687 | 3 | 0 | 3 |
| ERRFI1 | DDIT3 | 0.770475 | 3 | 0 | 3 |
| ERRFI1 | ARMCX2 | 0.765314 | 3 | 0 | 3 |
| ERRFI1 | PACSIN2 | 0.765213 | 3 | 0 | 3 |
| ERRFI1 | SGCB | 0.757705 | 4 | 0 | 4 |
| ERRFI1 | PSIP1 | 0.753461 | 3 | 0 | 3 |
| ERRFI1 | THOC1 | 0.751926 | 3 | 0 | 3 |
| ERRFI1 | RAB23 | 0.747712 | 4 | 0 | 4 |
| ERRFI1 | RASD2 | 0.742675 | 3 | 0 | 3 |
| ERRFI1 | HABP4 | 0.742014 | 4 | 0 | 4 |
| ERRFI1 | DOCK11 | 0.729626 | 3 | 0 | 3 |
| ERRFI1 | ITM2C | 0.728706 | 3 | 0 | 3 |
| ERRFI1 | DCHS1 | 0.724438 | 3 | 0 | 3 |
| ERRFI1 | JMY | 0.717064 | 4 | 0 | 3 |
| ERRFI1 | PCNP | 0.715946 | 3 | 0 | 3 |
| ERRFI1 | GLS | 0.71395 | 3 | 0 | 3 |
| ERRFI1 | ASAP1 | 0.710066 | 3 | 0 | 3 |
| ERRFI1 | KLF11 | 0.703294 | 5 | 0 | 3 |
| ERRFI1 | ITPKB | 0.702975 | 4 | 0 | 4 |
For details and further investigation, click here
