| Full name: single stranded DNA binding protein 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.1 | ||
| Entrez ID: 170463 | HGNC ID: HGNC:15676 | Ensembl Gene: ENSG00000130511 | OMIM ID: 607391 |
| Drug and gene relationship at DGIdb | |||
Expression of SSBP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSBP4 | 170463 | 229269_x_at | 0.5613 | 0.1759 | |
| GSE26886 | SSBP4 | 170463 | 223226_x_at | 1.5090 | 0.0000 | |
| GSE45670 | SSBP4 | 170463 | 229269_x_at | 0.3035 | 0.1087 | |
| GSE63941 | SSBP4 | 170463 | 229269_x_at | -0.6953 | 0.1025 | |
| GSE77861 | SSBP4 | 170463 | 223226_x_at | 0.4564 | 0.0400 | |
| GSE97050 | SSBP4 | 170463 | A_24_P410086 | 0.2591 | 0.3943 | |
| SRP007169 | SSBP4 | 170463 | RNAseq | 0.2698 | 0.5375 | |
| SRP008496 | SSBP4 | 170463 | RNAseq | 0.1480 | 0.6103 | |
| SRP064894 | SSBP4 | 170463 | RNAseq | 1.0311 | 0.0038 | |
| SRP133303 | SSBP4 | 170463 | RNAseq | -0.0660 | 0.7085 | |
| SRP159526 | SSBP4 | 170463 | RNAseq | 0.4410 | 0.0191 | |
| SRP193095 | SSBP4 | 170463 | RNAseq | 0.5568 | 0.0001 | |
| SRP219564 | SSBP4 | 170463 | RNAseq | 0.7374 | 0.2171 | |
| TCGA | SSBP4 | 170463 | RNAseq | 0.0611 | 0.3260 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SSBP4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SSBP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSBP4 | 170463 | 4 | 4 | 22 | |
| GSE20123 | SSBP4 | 170463 | 3 | 2 | 25 | |
| GSE43470 | SSBP4 | 170463 | 2 | 5 | 36 | |
| GSE46452 | SSBP4 | 170463 | 47 | 1 | 11 | |
| GSE47630 | SSBP4 | 170463 | 4 | 8 | 28 | |
| GSE54993 | SSBP4 | 170463 | 15 | 4 | 51 | |
| GSE54994 | SSBP4 | 170463 | 6 | 13 | 34 | |
| GSE60625 | SSBP4 | 170463 | 9 | 0 | 2 | |
| GSE74703 | SSBP4 | 170463 | 2 | 3 | 31 | |
| GSE74704 | SSBP4 | 170463 | 0 | 2 | 18 | |
| TCGA | SSBP4 | 170463 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 52; Total Number of normals: 328.
Somatic mutations of SSBP4:
Generating mutation plots.
Highly correlated genes for SSBP4:
Showing top 20/1301 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSBP4 | COMMD7 | 0.851946 | 3 | 0 | 3 |
| SSBP4 | MADD | 0.826583 | 3 | 0 | 3 |
| SSBP4 | FCHO1 | 0.821997 | 3 | 0 | 3 |
| SSBP4 | ZNF496 | 0.820535 | 5 | 0 | 5 |
| SSBP4 | EEF2 | 0.8168 | 3 | 0 | 3 |
| SSBP4 | PARVB | 0.815798 | 3 | 0 | 3 |
| SSBP4 | ISOC2 | 0.815535 | 3 | 0 | 3 |
| SSBP4 | NADK | 0.811004 | 3 | 0 | 3 |
| SSBP4 | MED22 | 0.8081 | 4 | 0 | 4 |
| SSBP4 | ZNF32 | 0.807245 | 3 | 0 | 3 |
| SSBP4 | TGFBRAP1 | 0.806955 | 3 | 0 | 3 |
| SSBP4 | SF1 | 0.806248 | 3 | 0 | 3 |
| SSBP4 | DENND4B | 0.803333 | 5 | 0 | 5 |
| SSBP4 | SIX5 | 0.803304 | 3 | 0 | 3 |
| SSBP4 | TMEM63B | 0.802581 | 3 | 0 | 3 |
| SSBP4 | SLC38A10 | 0.802546 | 4 | 0 | 4 |
| SSBP4 | NOL7 | 0.802189 | 3 | 0 | 3 |
| SSBP4 | DYRK2 | 0.80173 | 3 | 0 | 3 |
| SSBP4 | GRWD1 | 0.798918 | 3 | 0 | 3 |
| SSBP4 | PSMB4 | 0.798269 | 5 | 0 | 5 |
For details and further investigation, click here
