| Full name: paired box 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 5076 | HGNC ID: HGNC:8616 | Ensembl Gene: ENSG00000075891 | OMIM ID: 167409 |
| Drug and gene relationship at DGIdb | |||
Expression of PAX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAX2 | 5076 | 206229_x_at | -0.0270 | 0.9325 | |
| GSE20347 | PAX2 | 5076 | 206229_x_at | 0.0116 | 0.8880 | |
| GSE23400 | PAX2 | 5076 | 206229_x_at | -0.0604 | 0.0222 | |
| GSE26886 | PAX2 | 5076 | 206229_x_at | -0.1721 | 0.1692 | |
| GSE29001 | PAX2 | 5076 | 206228_at | 0.0963 | 0.7017 | |
| GSE38129 | PAX2 | 5076 | 206229_x_at | -0.0568 | 0.4768 | |
| GSE45670 | PAX2 | 5076 | 206229_x_at | -0.0098 | 0.9354 | |
| GSE53622 | PAX2 | 5076 | 56150 | -0.1170 | 0.1814 | |
| GSE53624 | PAX2 | 5076 | 56150 | -0.4499 | 0.0000 | |
| GSE63941 | PAX2 | 5076 | 206229_x_at | -0.1567 | 0.3687 | |
| GSE77861 | PAX2 | 5076 | 206229_x_at | -0.0054 | 0.9593 | |
| GSE97050 | PAX2 | 5076 | A_33_P3380850 | 0.0419 | 0.8846 | |
| TCGA | PAX2 | 5076 | RNAseq | 3.1890 | 0.0043 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PAX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAX2 | 5076 | 1 | 8 | 21 | |
| GSE20123 | PAX2 | 5076 | 1 | 7 | 22 | |
| GSE43470 | PAX2 | 5076 | 0 | 8 | 35 | |
| GSE46452 | PAX2 | 5076 | 0 | 11 | 48 | |
| GSE47630 | PAX2 | 5076 | 2 | 14 | 24 | |
| GSE54993 | PAX2 | 5076 | 8 | 0 | 62 | |
| GSE54994 | PAX2 | 5076 | 1 | 12 | 40 | |
| GSE60625 | PAX2 | 5076 | 0 | 0 | 11 | |
| GSE74703 | PAX2 | 5076 | 0 | 5 | 31 | |
| GSE74704 | PAX2 | 5076 | 0 | 4 | 16 | |
| TCGA | PAX2 | 5076 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of PAX2:
Generating mutation plots.
Highly correlated genes for PAX2:
Showing top 20/646 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAX2 | YY2 | 0.848486 | 3 | 0 | 3 |
| PAX2 | SLC22A31 | 0.831465 | 3 | 0 | 3 |
| PAX2 | RNF180 | 0.818875 | 3 | 0 | 3 |
| PAX2 | SCARA5 | 0.816735 | 3 | 0 | 3 |
| PAX2 | FAM171A2 | 0.812931 | 3 | 0 | 3 |
| PAX2 | TTC7A | 0.811906 | 3 | 0 | 3 |
| PAX2 | KRTAP6-1 | 0.809876 | 3 | 0 | 3 |
| PAX2 | GDF7 | 0.808411 | 3 | 0 | 3 |
| PAX2 | PRSS38 | 0.803181 | 3 | 0 | 3 |
| PAX2 | SALL3 | 0.794778 | 3 | 0 | 3 |
| PAX2 | C1QL2 | 0.79355 | 3 | 0 | 3 |
| PAX2 | SP8 | 0.788646 | 3 | 0 | 3 |
| PAX2 | DCDC1 | 0.78797 | 3 | 0 | 3 |
| PAX2 | LRSAM1 | 0.786675 | 3 | 0 | 3 |
| PAX2 | LBX2 | 0.786183 | 3 | 0 | 3 |
| PAX2 | MRGPRE | 0.782077 | 3 | 0 | 3 |
| PAX2 | STRC | 0.77831 | 3 | 0 | 3 |
| PAX2 | TSPAN11 | 0.777086 | 4 | 0 | 4 |
| PAX2 | ZC3H10 | 0.776771 | 3 | 0 | 3 |
| PAX2 | IL1F10 | 0.775225 | 3 | 0 | 3 |
For details and further investigation, click here
