| Full name: ring finger protein 180 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q12.3 | ||
| Entrez ID: 285671 | HGNC ID: HGNC:27752 | Ensembl Gene: ENSG00000164197 | OMIM ID: 616015 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF180:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF180 | 285671 | 242985_x_at | -1.5849 | 0.0285 | |
| GSE26886 | RNF180 | 285671 | 242985_x_at | -0.1993 | 0.4419 | |
| GSE45670 | RNF180 | 285671 | 242985_x_at | -0.8938 | 0.0000 | |
| GSE53622 | RNF180 | 285671 | 17710 | -0.0620 | 0.4723 | |
| GSE53624 | RNF180 | 285671 | 17710 | -0.1242 | 0.1979 | |
| GSE63941 | RNF180 | 285671 | 242985_x_at | -0.0077 | 0.9751 | |
| GSE77861 | RNF180 | 285671 | 242985_x_at | -0.1440 | 0.0965 | |
| GSE97050 | RNF180 | 285671 | A_33_P3321678 | -0.1288 | 0.5506 | |
| SRP007169 | RNF180 | 285671 | RNAseq | -1.1356 | 0.0390 | |
| SRP064894 | RNF180 | 285671 | RNAseq | -0.9144 | 0.0021 | |
| SRP133303 | RNF180 | 285671 | RNAseq | -0.6132 | 0.0012 | |
| SRP159526 | RNF180 | 285671 | RNAseq | -0.1818 | 0.6643 | |
| SRP193095 | RNF180 | 285671 | RNAseq | -0.0999 | 0.5673 | |
| SRP219564 | RNF180 | 285671 | RNAseq | -0.9268 | 0.1676 | |
| TCGA | RNF180 | 285671 | RNAseq | -1.1336 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RNF180 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF180:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF180 | 285671 | 0 | 14 | 16 | |
| GSE20123 | RNF180 | 285671 | 0 | 14 | 16 | |
| GSE43470 | RNF180 | 285671 | 1 | 13 | 29 | |
| GSE46452 | RNF180 | 285671 | 0 | 28 | 31 | |
| GSE47630 | RNF180 | 285671 | 2 | 17 | 21 | |
| GSE54993 | RNF180 | 285671 | 8 | 1 | 61 | |
| GSE54994 | RNF180 | 285671 | 1 | 19 | 33 | |
| GSE60625 | RNF180 | 285671 | 0 | 0 | 11 | |
| GSE74703 | RNF180 | 285671 | 1 | 9 | 26 | |
| GSE74704 | RNF180 | 285671 | 0 | 7 | 13 | |
| TCGA | RNF180 | 285671 | 5 | 50 | 41 |
Total number of gains: 18; Total number of losses: 172; Total Number of normals: 298.
Somatic mutations of RNF180:
Generating mutation plots.
Highly correlated genes for RNF180:
Showing top 20/383 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF180 | YY2 | 0.886056 | 3 | 0 | 3 |
| RNF180 | SPRED3 | 0.884473 | 3 | 0 | 3 |
| RNF180 | GRIK4 | 0.8606 | 3 | 0 | 3 |
| RNF180 | LBX2 | 0.855007 | 3 | 0 | 3 |
| RNF180 | ST8SIA1 | 0.843408 | 3 | 0 | 3 |
| RNF180 | PRSS38 | 0.842895 | 3 | 0 | 3 |
| RNF180 | SLC22A7 | 0.841863 | 3 | 0 | 3 |
| RNF180 | SIM1 | 0.839147 | 3 | 0 | 3 |
| RNF180 | C9orf153 | 0.831828 | 3 | 0 | 3 |
| RNF180 | PLA2G2C | 0.831809 | 3 | 0 | 3 |
| RNF180 | CLTCL1 | 0.820315 | 3 | 0 | 3 |
| RNF180 | PAX2 | 0.818875 | 3 | 0 | 3 |
| RNF180 | STRC | 0.818172 | 3 | 0 | 3 |
| RNF180 | TATDN3 | 0.816753 | 3 | 0 | 3 |
| RNF180 | KIRREL2 | 0.81662 | 3 | 0 | 3 |
| RNF180 | OR2T27 | 0.815745 | 3 | 0 | 3 |
| RNF180 | TPO | 0.815147 | 3 | 0 | 3 |
| RNF180 | FOXE3 | 0.814479 | 3 | 0 | 3 |
| RNF180 | NOBOX | 0.809519 | 3 | 0 | 3 |
| RNF180 | KCNH3 | 0.809368 | 3 | 0 | 3 |
For details and further investigation, click here
