| Full name: PAX3 and PAX7 binding protein 1 | Alias Symbol: GCFC|fSAP105 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 94104 | HGNC ID: HGNC:13579 | Ensembl Gene: ENSG00000159086 | OMIM ID: 617621 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PAXBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAXBP1 | 94104 | 218515_at | -0.0749 | 0.8493 | |
| GSE20347 | PAXBP1 | 94104 | 218515_at | 0.2092 | 0.2445 | |
| GSE23400 | PAXBP1 | 94104 | 218515_at | 0.1754 | 0.0320 | |
| GSE26886 | PAXBP1 | 94104 | 218515_at | -0.9213 | 0.0081 | |
| GSE29001 | PAXBP1 | 94104 | 218515_at | 0.1339 | 0.6431 | |
| GSE38129 | PAXBP1 | 94104 | 218515_at | 0.2131 | 0.1736 | |
| GSE45670 | PAXBP1 | 94104 | 218515_at | -0.1670 | 0.2774 | |
| GSE53622 | PAXBP1 | 94104 | 128408 | -0.0719 | 0.2470 | |
| GSE53624 | PAXBP1 | 94104 | 128408 | -0.0504 | 0.4808 | |
| GSE63941 | PAXBP1 | 94104 | 218515_at | -0.2273 | 0.5816 | |
| GSE77861 | PAXBP1 | 94104 | 218515_at | -0.1281 | 0.6065 | |
| SRP007169 | PAXBP1 | 94104 | RNAseq | 0.1250 | 0.7253 | |
| SRP008496 | PAXBP1 | 94104 | RNAseq | 0.4746 | 0.0827 | |
| SRP064894 | PAXBP1 | 94104 | RNAseq | 0.0696 | 0.7559 | |
| SRP133303 | PAXBP1 | 94104 | RNAseq | -0.0774 | 0.5414 | |
| SRP159526 | PAXBP1 | 94104 | RNAseq | 0.2721 | 0.3781 | |
| SRP193095 | PAXBP1 | 94104 | RNAseq | 0.0262 | 0.7681 | |
| SRP219564 | PAXBP1 | 94104 | RNAseq | -0.3881 | 0.0714 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PAXBP1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PAXBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAXBP1 | 94104 | 2 | 7 | 21 | |
| GSE20123 | PAXBP1 | 94104 | 2 | 8 | 20 | |
| GSE43470 | PAXBP1 | 94104 | 3 | 9 | 31 | |
| GSE46452 | PAXBP1 | 94104 | 1 | 21 | 37 | |
| GSE47630 | PAXBP1 | 94104 | 6 | 17 | 17 | |
| GSE54993 | PAXBP1 | 94104 | 9 | 1 | 60 | |
| GSE54994 | PAXBP1 | 94104 | 1 | 9 | 43 | |
| GSE60625 | PAXBP1 | 94104 | 0 | 0 | 11 | |
| GSE74703 | PAXBP1 | 94104 | 3 | 6 | 27 | |
| GSE74704 | PAXBP1 | 94104 | 1 | 4 | 15 | |
| TCGA | PAXBP1 | 94104 | 9 | 36 | 51 |
Total number of gains: 37; Total number of losses: 118; Total Number of normals: 333.
Somatic mutations of PAXBP1:
Generating mutation plots.
Highly correlated genes for PAXBP1:
Showing top 20/96 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAXBP1 | GABPB2 | 0.69248 | 3 | 0 | 3 |
| PAXBP1 | KIAA2026 | 0.650536 | 3 | 0 | 3 |
| PAXBP1 | UBN2 | 0.646111 | 5 | 0 | 4 |
| PAXBP1 | DPY19L3 | 0.634685 | 3 | 0 | 3 |
| PAXBP1 | ALG6 | 0.63368 | 5 | 0 | 4 |
| PAXBP1 | ZSCAN16 | 0.623811 | 5 | 0 | 4 |
| PAXBP1 | ZNF606 | 0.618739 | 4 | 0 | 3 |
| PAXBP1 | SMARCAD1 | 0.61782 | 3 | 0 | 3 |
| PAXBP1 | ZNF416 | 0.614685 | 3 | 0 | 3 |
| PAXBP1 | ZNF398 | 0.613212 | 3 | 0 | 3 |
| PAXBP1 | GKAP1 | 0.611636 | 3 | 0 | 3 |
| PAXBP1 | PDIK1L | 0.60982 | 3 | 0 | 3 |
| PAXBP1 | HDAC6 | 0.604023 | 4 | 0 | 3 |
| PAXBP1 | LMBRD2 | 0.603186 | 3 | 0 | 3 |
| PAXBP1 | TXLNG | 0.601897 | 3 | 0 | 3 |
| PAXBP1 | EPM2AIP1 | 0.59775 | 4 | 0 | 3 |
| PAXBP1 | TXNDC16 | 0.595188 | 4 | 0 | 3 |
| PAXBP1 | SRSF7 | 0.592082 | 5 | 0 | 3 |
| PAXBP1 | BOD1L1 | 0.591646 | 3 | 0 | 3 |
| PAXBP1 | ZFP30 | 0.591321 | 4 | 0 | 3 |
For details and further investigation, click here
