| Full name: zinc finger protein 398 | Alias Symbol: ZER6|KIAA1339|P51|P71 | ||
| Type: protein-coding gene | Cytoband: 7q35 | ||
| Entrez ID: 57541 | HGNC ID: HGNC:18373 | Ensembl Gene: ENSG00000197024 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF398:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF398 | 57541 | 228145_s_at | -0.3779 | 0.6450 | |
| GSE26886 | ZNF398 | 57541 | 228145_s_at | -0.8115 | 0.0356 | |
| GSE45670 | ZNF398 | 57541 | 228145_s_at | -0.2038 | 0.2449 | |
| GSE53622 | ZNF398 | 57541 | 78919 | -0.5483 | 0.0000 | |
| GSE53624 | ZNF398 | 57541 | 78919 | -0.4343 | 0.0000 | |
| GSE63941 | ZNF398 | 57541 | 228145_s_at | -0.6896 | 0.0285 | |
| GSE77861 | ZNF398 | 57541 | 228145_s_at | 0.2023 | 0.3971 | |
| GSE97050 | ZNF398 | 57541 | A_32_P151875 | -0.1780 | 0.4338 | |
| SRP007169 | ZNF398 | 57541 | RNAseq | -0.2400 | 0.5401 | |
| SRP008496 | ZNF398 | 57541 | RNAseq | -0.2949 | 0.2952 | |
| SRP064894 | ZNF398 | 57541 | RNAseq | -0.4891 | 0.0003 | |
| SRP133303 | ZNF398 | 57541 | RNAseq | -0.3084 | 0.0241 | |
| SRP159526 | ZNF398 | 57541 | RNAseq | -0.1324 | 0.5926 | |
| SRP193095 | ZNF398 | 57541 | RNAseq | -0.6610 | 0.0000 | |
| SRP219564 | ZNF398 | 57541 | RNAseq | -0.8200 | 0.0494 | |
| TCGA | ZNF398 | 57541 | RNAseq | -0.0608 | 0.2861 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF398 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF398:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF398 | 57541 | 2 | 3 | 25 | |
| GSE20123 | ZNF398 | 57541 | 2 | 3 | 25 | |
| GSE43470 | ZNF398 | 57541 | 2 | 5 | 36 | |
| GSE46452 | ZNF398 | 57541 | 7 | 2 | 50 | |
| GSE47630 | ZNF398 | 57541 | 6 | 8 | 26 | |
| GSE54993 | ZNF398 | 57541 | 3 | 3 | 64 | |
| GSE54994 | ZNF398 | 57541 | 5 | 8 | 40 | |
| GSE60625 | ZNF398 | 57541 | 0 | 0 | 11 | |
| GSE74703 | ZNF398 | 57541 | 2 | 4 | 30 | |
| GSE74704 | ZNF398 | 57541 | 1 | 3 | 16 | |
| TCGA | ZNF398 | 57541 | 26 | 27 | 43 |
Total number of gains: 56; Total number of losses: 66; Total Number of normals: 366.
Somatic mutations of ZNF398:
Generating mutation plots.
Highly correlated genes for ZNF398:
Showing top 20/332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF398 | SLC38A1 | 0.784816 | 3 | 0 | 3 |
| ZNF398 | MIF4GD | 0.762387 | 3 | 0 | 3 |
| ZNF398 | PIGB | 0.755937 | 3 | 0 | 3 |
| ZNF398 | SYPL1 | 0.75398 | 3 | 0 | 3 |
| ZNF398 | PRDM2 | 0.749378 | 3 | 0 | 3 |
| ZNF398 | RWDD2B | 0.747082 | 3 | 0 | 3 |
| ZNF398 | RSBN1 | 0.745962 | 3 | 0 | 3 |
| ZNF398 | C2CD2 | 0.741353 | 3 | 0 | 3 |
| ZNF398 | FRMD6 | 0.740173 | 3 | 0 | 3 |
| ZNF398 | GSPT2 | 0.736044 | 3 | 0 | 3 |
| ZNF398 | UPF3B | 0.73204 | 3 | 0 | 3 |
| ZNF398 | CNOT4 | 0.727859 | 5 | 0 | 5 |
| ZNF398 | MBOAT1 | 0.727514 | 3 | 0 | 3 |
| ZNF398 | GATAD1 | 0.722219 | 3 | 0 | 3 |
| ZNF398 | ARL6 | 0.718699 | 3 | 0 | 3 |
| ZNF398 | TACC2 | 0.717414 | 4 | 0 | 3 |
| ZNF398 | ZDHHC6 | 0.715848 | 3 | 0 | 3 |
| ZNF398 | BMPR2 | 0.710855 | 3 | 0 | 3 |
| ZNF398 | C21orf91 | 0.705275 | 3 | 0 | 3 |
| ZNF398 | COX5A | 0.704678 | 4 | 0 | 3 |
For details and further investigation, click here
